Curcumin prevents corticosterone-induced neurotoxicity and abnormalities of neuroplasticity via 5-HT receptor pathway

Journal of Neurochemistry

Volumn 118, Issue 5, 2011, Pages 784-795

  Xu, Ying ^a,b,d   Li, Shan ^a,c   Vernon, Matthew M ^a   Pan, Jianchun ^c   Chen, Ling ^c   Barish, Philip A ^a   Zhang, Yuan ^c   Acharya, Abhinav P ^a   Yu, Jie ^c   Govindarajan, Subramaniam S ^a   Boykin, Erin ^a   Pan, Xiaoyu ^c   O'Donnell, James M ^b   Ogle, William O ^a  

^a University of Florida   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

^c WENZHOU MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

5 HT receptors; cAMP; corticosterone; curcumin; neuronal plasticity

Indexed keywords

CORTICOSTERONE; CURCUMIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; RS 39604; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 4 ANTAGONIST; SEROTONIN 4 RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN RECEPTOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL STRUCTURE; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; GENE SEQUENCE; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CORTICOSTERONE; CREB-BINDING PROTEIN; CURCUMIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOXETINE; GENE EXPRESSION REGULATION; NEURONAL PLASTICITY; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT1; RNA, MESSENGER; SEROTONIN UPTAKE INHIBITORS; SIGNAL TRANSDUCTION; TRANSFECTION;

CURCUMA LONGA;

EID: 80051786861     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07356.x     Document Type: Article

References (47)

1. Alfarez N. D., Simoni A. D., Velzing E. H., Bracey E., Joels M., Edwards F. A., and, Krugers H. J., (2009) Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons. Hippocampus 19, 828-836.
2. 1A receptors in animal and human brain. Neuropharmacology 52, 695-707. (Pubitemid 46227474)
3. 1A autoreceptors after chronic unpredictable stress. Eur. Neuropsychopharmacol. 19, 215-228.
4. Bessa J. M., Ferreira D., Melo I., Marques F., Cerqueira J. J., Palha J. A., Almeida O. F., and, Sousa N., (2009) The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling. Mol. Psychiatry 14, 764-773.
5. Cai X., Flores-Hernandez J., Feng J., and, Yan Z., (2002) Activity-dependent bidirectional regulation of GABA(A) receptor channels by the 5-HT(4) receptor-mediated signalling in rat prefrontal cortical pyramidal neurons. J. Physiol. 540, 743-59. (Pubitemid 35190149)
6. Dooley A. E., Pappas I. S., and, Parnavelas J. G., (1997) Serotonin promotes the survival of cortical glutamatergic neurons in vitro. Exp. Neurol. 148, 205-214. (Pubitemid 127445127)
7. Fricker A. D., Rios C., Devi L. A., and, Gomes I., (2005) Serotonin receptor activation leads to neurite outgrowth and neuronal survival. Mol. Brain Res. 138, 228-235. (Pubitemid 41138042)
8. Gorski J. A., Zeiler S. R., Tamowski S., and, Jones K. R., (2003) Brain-derived neurotrophic factors is required for the maintenance of cortical dendrites. J. Neurosci. 23, 6856-6865. (Pubitemid 36951214)
9. Greene J., Banasr M., Lee B., Warner-Schmidt J., and, Duman R. S., (2009) Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization. Neuropsychopharmacology. 34, 2459-2468.
10. Holmes A., (2008) Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. Neurosci. Biobehav. Rev. 32, 1293-1314.
11. Iyo A. H., Kieran N., Chandran A., Albert P. R., Wicks I., Bissette G., and, Austin M. C., (2009) Differential regulation of the serotonin 1A transcriptional modulators five prime repressor element under dual depression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress. Neuroscience 10, 1119-1127.
12. Johnson B. N., and, Yamamoto B. K., (2009) Chronic unpredictable stress augments +3,4-methylenedioxymethamphetamine-induced monoamine depletions: the role of corticosterone. Neuroscience 159, 1233-1243.
13. Jugloff D. G., Jung P. B., Purushotham D., Logan R., and, Eubanks J. H., (2005) Increased dendritic complexity and axonal length in cultured mouse crotical neurons overexpressing methyl-CpG-binding protein MeCP2. Neurobiol. Dis. 19, 18-27. (Pubitemid 40544720)
14. Kemp A., and, Manahan-Vaughan D., (2005) The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo. Cereb. Cortex 15, 1037-1043. (Pubitemid 40848072)
15. King M. V., Marsden C. A., and, Fone K. C., (2008) A role for the 5-HT (1A), 5-HT4 and 5-HT6 receptors in learning and memory. Trends Pharmacol. Sci. 29, 482-492.
16. Klempin F., Babu H., Tonelli Dde P., Alarcon E., Fabel K., and, Kempermann G., (2010) Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. Front Mol Neurosci. 3, 1-11.
17. Laifenfeld D., Klein E., and, Ben-Shachar D., (2002) Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms. J. Neurochem. 83, 1054-1064. (Pubitemid 35397115)
18. 2A receptor mediated neuronal activation within the paraventricular nucleus of the hypothalamus is desensitized following prolonged glucocorticoid treatment. Eur. J. Pharmacol. 602, 54-57.
19. Leonard B. E., (2005) The HPA and immune axes in stress: the involvement of the serotonergic system. Eur. Psychiatry 20, 302-306.
20. Li Y. F., Liu Y. Q., Huang W. C., and, Luo Z. P., (2003) Cytoprotective effect is one of common action pathways for antidepressants. Acta Pharmacol. Sin. 24, 996-1000.
21. 4) receptor agonists are putative antidepressants with a rapid onset of action. Neuron 55, 712-725. (Pubitemid 47334877)
22. Lucas G., Du J., Romeas T., Mnie-Filali O., Haddjeri N., Piñeyro G., and, Debonnel G., (2010) Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat. PLoS One. 5, 9253.
23. Mele T., Carman-Krzan M., and, Juric D. M., (2010) Regulatory role of monoamine neurotransmitters in astrocytic NT-3 synthesis. Int. J. Dev. Neurosci. 28, 13-19.
24. 4 receptors or 5-HT uptake inhibition: short- and long-term memory. Behav. Brain Res. 184, 81-90. (Pubitemid 47411590)
25. Motterlini R., Foresti R., Bassi R., and, Green C. J., (2000) Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic. Biol. Med. 28, 1303-1312. (Pubitemid 30417475)
26. Murphy D. D., and, Segal M., (1996) Regulation of dendritic spine density in cultured rat hippocampal neurons by steroid hormaones. J. Neurosci. 16, 4059-4068. (Pubitemid 26192402)
27. Nestler E. J., Terwilliger R. Z., and, Duman R. S., (1989) Chronic antidepressant administration alters the subcellular distribution of cyclic AMP-dependent protein kinase in rat frontal cortex. J. Neurochem. 53, 1644-1647. (Pubitemid 19267038)
28. Nishi M., Whitaker-Azmitia P. M., and, Azmitia E. C., (1996) Enhanced synaptophysin immunoreactivity in rat hippocampal culture by 5-HT1a agonist, S100b, and corticosteroid receptor agonists. Synapse 23, 1-9.
29. Pitchot W., Herrera C., and, Ansseau M., (2001) HPA axis dysfunction in major depression: relationship to 5-HT1a receptor activiy. Neuropsychobiology 44, 74-77. (Pubitemid 32722303)
30. Popoli M., Brunello N., Perez J., and, Racagni G., (2000) Second messenger-regulated protein kinases in the brain, their functional role and the action of antidepressant drugs. J. Neurochem. 74, 21-33. (Pubitemid 30012751)
31. Ramakrishnan R., Sheeladevi R., and, Namasivayam A., (2009) Regulation of protein kinases and coregulatory interplay of S-100β and serotonin transporter on serotonin levels in diabetic rat brain. J. Neurosci. Res. 87, 246-259.
32. Reddy P. H., Mani G., Park B. S., Jacques J., Murdoch G., Whetsell W. J., Kaye J., and, Manczak M., (2005) Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction. J. Alzheimers Dis. 7, 103-117. (Pubitemid 40592184)
33. Reines A., Cereseto M., Ferrero A., Sifonios L., Podesta M. F., and, Wikinski S., (2008) Maintenance treatment with fluoxetine is necessary to sustain normal levels of synaptic markers in an experimental model of depression: correlation with behavioral response. Neuropsychopharmacology 33, 1896-1908. (Pubitemid 351832608)
34. Sakaue M., Somboonthum P., Nishihara B., Koyama Y., Hashimoto H., Baba A., and, Matsuda T., (2000) Postsynaptic 5-hydroxytryptamine(1A) receptor activation increases in vivo dopamine release in rat prefrontal cortex. Br. J. Pharmacol. 129, 1028-1034. (Pubitemid 30142918)
35. Sapolsky R., Brooke S., and, Stein-Gehrens B., (1995) Methodologic issues in studying glucocorticoid-induced damage to neurons. J. Neurosci. Methods 58, 1-15.
36. Suresh D., and, Srinivasan K., (2010) Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats. Indian J. Med. Res. 131, 682-691.
37. Thiyagarajan M., and, Sharma S. S., (2004) Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Life Sci. 74, 969-985. (Pubitemid 37522132)
38. Varea E., Blasco-Ibáñez M. J., Gõmez-Climent M. A., Castillo-Gõmez E., Crespo C., Marti'nez-Guijarro F. J., and, Nácher J., (2007) Chronic fluoxetine treatment increases the expression of PSA-NCAM in the medial prefrontal cortex. Neuropsychopharmacology 32, 803-821.
39. 2 receptors. Eur. J. Pharmacol. 578, 43-50. (Pubitemid 350179755)
40. Xie Z., Cahill M. E., and, Penzes P., (2010) Kalirin loss results in cortical morphological alterations. Mol. Cell. Neurosci. 43, 81-89.
41. Xu Y., Ku B. S., Yao H. Y., Lin Y. H., Ma X., Zhang Y. H., and, Li X. J., (2005a) The effects of curcumin on depressive-like behaviors in mice. Eur. J. Pharmacol. 518, 40-46. (Pubitemid 40968146)
42. Xu Y., Ku B. S., Yao H. Y., Lin Y. H., Ma X., Zhang Y. H., and, Li X. J., (2005b) Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats. Pharmacol. Biochem. Behav. 82, 200-206. (Pubitemid 41423504)
43. Xu Y., Ku B. S., Tie L., Yao H. Y., Jiang W. G., Ma X., and, Li X. J., (2006) Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. Brain Res. 1122, 56-64. (Pubitemid 44708120)
44. Xu Y., Ku B. S., Cui L., LiX J., Barish P. A., Foster T. C., and, Ogle W. O., (2007) Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain derived neurotrophic factor expression in chronically stressed rats. Brain Res. 1162, 9-18. (Pubitemid 47088372)
45. Xu Y., Lin D., Li S., Li G. W., Shyamala S. G., Barish P. A., Vernon M. M., Pan J. C., and, Ogle W. O., (2009) Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress. Neuropharmacology 57, 463-471.
46. Yaniv S. P., Ben-Shachar D., and, Klein E., (2008) Norepinephrine- glucocorticoids interaction does not annul the opposite effects of the individual treatments on cellular plasticity in neuroblastoma cells. Eur. J. Pharmacol. 596, 14-24.
47. Zhou H., Li X., and, Gao M., (2009) Curcumin protects PC12 cells from corticosterone-induced cytotoxicity: possible involvement of the ERK1/2 pathway. Basic Clin. Pharmacol. Toxicol. 104, 236-40.