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Volumn 9, Issue 14, 2008, Pages 2553-2559

Colostrinin™: A naturally occurring compound derived from mammalian colostrum with efficacy in treatment of neurodegenerative diseases, including Alzheimer's

Author keywords

amyloid; Colostrinin ; Neurodegenerative disease; Neuroprotection; Nutraceutical; Reduced oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN; ANTIDEPRESSANT AGENT; COGNISURE; COLOSTRININ; NUTRACEUTICAL; PLACEBO; PSYCHOTROPIC AGENT; SELENIUM; UNCLASSIFIED DRUG; COLOSTRININE; PEPTIDE;

EID: 54349088496     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.9.14.2553     Document Type: Article
Times cited : (11)

References (34)
  • 1
    • 0041781821 scopus 로고    scopus 로고
    • The quest for a smart pill
    • Hall SH. The quest for a smart pill. Sci Am 2003;289(3):54-65
    • (2003) Sci Am , vol.289 , Issue.3 , pp. 54-65
    • Hall, S.H.1
  • 2
    • 47849130514 scopus 로고    scopus 로고
    • Colostrinin™ an oxidative stress modulator for prevention and treatment of age-related disorders
    • Boldogh I, Kruzel ML. Colostrinin™ an oxidative stress modulator for prevention and treatment of age-related disorders. J Alzheimers Dis 2008;13(3):303-21
    • (2008) J Alzheimers Dis , vol.13 , Issue.3 , pp. 303-321
    • Boldogh, I.1    Kruzel, M.L.2
  • 3
    • 14244264532 scopus 로고    scopus 로고
    • Technology evaluation: Colostrinin, ReGen
    • Rattray M. Technology evaluation: colostrinin, ReGen. Curr Opin Mol Ther 2005;7(1)78-84
    • (2005) Curr Opin Mol Ther , vol.7 , Issue.1 , pp. 78-84
    • Rattray, M.1
  • 4
    • 54349092657 scopus 로고    scopus 로고
    • Diagnostic and statistical manual of mental disorders (IV-TR)
    • American Psychiatric Association APA, revised. APA, Washington, DC;
    • American Psychiatric Association (APA). Diagnostic and statistical manual of mental disorders (IV-TR). 4th edition-text revised. APA, Washington, DC; 2000
    • (2000) 4th edition-text
  • 5
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease-report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G, Drachman DA, Folstein M, et al. Clinical diagnosis of Alzheimer's disease-report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-44
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.A.2    Folstein, M.3
  • 6
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDS-ADRDA criteria
    • Dubois B, Feldman HF, Claudia Jacava C, et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007;6:734-46
    • (2007) Lancet Neurol , vol.6 , pp. 734-746
    • Dubois, B.1    Feldman, H.F.2    Claudia Jacava, C.3
  • 7
    • 0029758192 scopus 로고    scopus 로고
    • Use of structural imaging to study the progression of Alzheimer's disease
    • Smith AD, Jobst KA. Use of structural imaging to study the progression of Alzheimer's disease. Br Med Bull 1996;52(3):575-86
    • (1996) Br Med Bull , vol.52 , Issue.3 , pp. 575-586
    • Smith, A.D.1    Jobst, K.A.2
  • 8
    • 0033998977 scopus 로고    scopus 로고
    • Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: Final analysis of a US multicentre open-label study
    • Rogers SL, Doody RS, Pratt RD, Leni JR. Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: final analysis of a US multicentre open-label study. Eur Neuropsychopharmacol 2000;10(3):195-203
    • (2000) Eur Neuropsychopharmacol , vol.10 , Issue.3 , pp. 195-203
    • Rogers, S.L.1    Doody, R.S.2    Pratt, R.D.3    Leni, J.R.4
  • 9
    • 34548285795 scopus 로고    scopus 로고
    • Efficacy and safety of donepezil over 3 years: An open-label, multicentre study in patients with Alzheimer's disease
    • Burns A, Gauthier S, Perdomo C. Efficacy and safety of donepezil over 3 years: an open-label, multicentre study in patients with Alzheimer's disease. Int J Geriatr Psychiatry 2007;22(8):806-12
    • (2007) Int J Geriatr Psychiatry , vol.22 , Issue.8 , pp. 806-812
    • Burns, A.1    Gauthier, S.2    Perdomo, C.3
  • 10
    • 43049165571 scopus 로고    scopus 로고
    • Current approaches in the treatment of Alzheimer's disease
    • Shah RS, Lee HG, Siongwei Z, et al. Current approaches in the treatment of Alzheimer's disease. Biomed Pharmacother 2008;62(4):199-207
    • (2008) Biomed Pharmacother , vol.62 , Issue.4 , pp. 199-207
    • Shah, R.S.1    Lee, H.G.2    Siongwei, Z.3
  • 11
    • 0037320324 scopus 로고    scopus 로고
    • Antioxidant vitamin intake and risk of Alzheimer disease
    • Luchsinger JA, Tang MX, Shea S, Mayeux R. Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol 2003;60(2):203-8
    • (2003) Arch Neurol , vol.60 , Issue.2 , pp. 203-208
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 12
    • 0016325501 scopus 로고
    • Isolation and characterization of a proline-rich polypeptide from ovine colostrums
    • Janusz M, Lisowski J, Franek F. Isolation and characterization of a proline-rich polypeptide from ovine colostrums. FEBS Lett 1974;49:276-9
    • (1974) FEBS Lett , vol.49 , pp. 276-279
    • Janusz, M.1    Lisowski, J.2    Franek, F.3
  • 13
    • 0035704877 scopus 로고    scopus 로고
    • Towards an understanding of biological role of colostrinin peptides
    • Kruzel M, Janusz M, Lisowski J, et al. Towards an understanding of biological role of colostrinin peptides. J Mol Neurosci 2001;17:115-25
    • (2001) J Mol Neurosci , vol.17 , pp. 115-125
    • Kruzel, M.1    Janusz, M.2    Lisowski, J.3
  • 14
    • 7444241410 scopus 로고    scopus 로고
    • The alcohol induced conformational changes in casein micelles: A new challenge for the purification of colostrinin
    • Kruzel ML, Polanowski A, Wilusz T, et al. The alcohol induced conformational changes in casein micelles: a new challenge for the purification of colostrinin. Protein J 2004;23:127-33
    • (2004) Protein J , vol.23 , pp. 127-133
    • Kruzel, M.L.1    Polanowski, A.2    Wilusz, T.3
  • 15
    • 0030333879 scopus 로고    scopus 로고
    • Colostrinin: A proline-rich polypeptide from ovine colostrum is a modest cytokine inducer in human leukocytes
    • Inglot AD, Janusz M, Lisowski J. Colostrinin: a proline-rich polypeptide from ovine colostrum is a modest cytokine inducer in human leukocytes. Arch Immunol Ther Exp 1996;44(4):215-24
    • (1996) Arch Immunol Ther Exp , vol.44 , Issue.4 , pp. 215-224
    • Inglot, A.D.1    Janusz, M.2    Lisowski, J.3
  • 16
    • 0027792455 scopus 로고
    • Proline-rich polypeptide (PRP) an immunomodulatory peptide from ovine colostrums
    • Janusz M, Lisowski J. Proline-rich polypeptide (PRP) an immunomodulatory peptide from ovine colostrums. Arch Immunol Ther Exp 1993;41:275-9
    • (1993) Arch Immunol Ther Exp , vol.41 , pp. 275-279
    • Janusz, M.1    Lisowski, J.2
  • 17
    • 33749315286 scopus 로고    scopus 로고
    • Colostrinin decreases spontaneous and induced mutation frequencies at the hprt locus in Chinese hamster V79 cells
    • Bacsi A, Aguilera-Aguirre L, German P, et al. Colostrinin decreases spontaneous and induced mutation frequencies at the hprt locus in Chinese hamster V79 cells. J Exp Ther Oncol 2006;5:249-59
    • (2006) J Exp Ther Oncol , vol.5 , pp. 249-259
    • Bacsi, A.1    Aguilera-Aguirre, L.2    German, P.3
  • 18
    • 46849088584 scopus 로고    scopus 로고
    • Colostrinin decreases hypersensitivity and allergic responses to common allergens
    • Boldogh I, Aguilera-Aguirre L, Bacsi A, et al. Colostrinin decreases hypersensitivity and allergic responses to common allergens. Int Arch Allergy Immunol 2008;146(4):298-306
    • (2008) Int Arch Allergy Immunol , vol.146 , Issue.4 , pp. 298-306
    • Boldogh, I.1    Aguilera-Aguirre, L.2    Bacsi, A.3
  • 19
    • 29944443102 scopus 로고    scopus 로고
    • Colostrinin-driven neurite outgrowth requires p53 activation in PC12 cells
    • Bacsi A, Stanton GJ, Hughes TK, et al. Colostrinin-driven neurite outgrowth requires p53 activation in PC12 cells. Cell Mol Neurobiol 2005;25:1123-39
    • (2005) Cell Mol Neurobiol , vol.25 , pp. 1123-1139
    • Bacsi, A.1    Stanton, G.J.2    Hughes, T.K.3
  • 20
    • 33847418386 scopus 로고    scopus 로고
    • Colostrinin delays the onset of proliferative senescence of diploid murine fibroblast cells
    • Bacsi A, Woodberry M, Kruzel ML, Boldogh I. Colostrinin delays the onset of proliferative senescence of diploid murine fibroblast cells. Neuropeptides 2007;41:93-101
    • (2007) Neuropeptides , vol.41 , pp. 93-101
    • Bacsi, A.1    Woodberry, M.2    Kruzel, M.L.3    Boldogh, I.4
  • 21
    • 23144442472 scopus 로고    scopus 로고
    • Protective effect of colostrinin on neuroblastoma cell survival is due to reduced aggregation of beta-amyloid
    • Schuster D, Rajendran A, Hui SW, et al. Protective effect of colostrinin on neuroblastoma cell survival is due to reduced aggregation of beta-amyloid. Neuropeptides 2005;39(4)19-426
    • (2005) Neuropeptides , vol.39 , Issue.4 , pp. 19-426
    • Schuster, D.1    Rajendran, A.2    Hui, S.W.3
  • 22
    • 0008176081 scopus 로고    scopus 로고
    • Antioxidant and cell-differentiating activity of colostrinin and its component peptides (CCP) in cell culture
    • Boldogh ITK, Hughes TK, Georgiades JA, Stanton J. Antioxidant and cell-differentiating activity of colostrinin and its component peptides (CCP) in cell culture. Psychogeriatr Ann 2001;4:57-65
    • (2001) Psychogeriatr Ann , vol.4 , pp. 57-65
    • Boldogh, I.T.K.1    Hughes, T.K.2    Georgiades, J.A.3    Stanton, J.4
  • 23
    • 0038279954 scopus 로고    scopus 로고
    • Modulation of 4HNE-mediated signaling by proline-rich peptides from ovine colostrums
    • Boldogh I, Liebenthal D, Hughes TK, et al. Modulation of 4HNE-mediated signaling by proline-rich peptides from ovine colostrums. J Mol Neurosci 2003;20:125-34
    • (2003) J Mol Neurosci , vol.20 , pp. 125-134
    • Boldogh, I.1    Liebenthal, D.2    Hughes, T.K.3
  • 24
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 25
    • 0006198863 scopus 로고    scopus 로고
    • Biomarkers of free radical damage applications in experimental animals and in humans
    • Dr Zwart LL, Meerman H, Commandeur JN, Vermeulen NP. Biomarkers of free radical damage applications in experimental animals and in humans. Free Radic Biol Med 1999;26:202-26
    • (1999) Free Radic Biol Med , vol.26 , pp. 202-226
    • Dr Zwart, L.L.1    Meerman, H.2    Commandeur, J.N.3    Vermeulen, N.P.4
  • 26
    • 33646846678 scopus 로고    scopus 로고
    • Enhancement of long-term memory retention by Colostrinin in one-day-old chicks trained on a weak passive avoidance learning paradigm
    • Stewart MG, Banks D. Enhancement of long-term memory retention by Colostrinin in one-day-old chicks trained on a weak passive avoidance learning paradigm. Neurobiol Learn Mem 2006;86:66-71
    • (2006) Neurobiol Learn Mem , vol.86 , pp. 66-71
    • Stewart, M.G.1    Banks, D.2
  • 27
    • 0032872681 scopus 로고    scopus 로고
    • Colostrinin, a polypeptide isolated from early milk, facilitates learning and memory in rats
    • Popik P, Bobula PB, Janusz M, et al. Colostrinin, a polypeptide isolated from early milk, facilitates learning and memory in rats. Pharmacol Biochem Behav 1999;64:183-9
    • (1999) Pharmacol Biochem Behav , vol.64 , pp. 183-189
    • Popik, P.1    Bobula, P.B.2    Janusz, M.3
  • 28
    • 47849113869 scopus 로고    scopus 로고
    • Colostrinin™ increases the lifespan and neurological performance of mice
    • Boldogh I, Bacsi L, Agulera-Aguirre L, et al. Colostrinin™ increases the lifespan and neurological performance of mice. Neurodegener Dis 2007;4(Suppl. 1):264
    • (2007) Neurodegener Dis , vol.4 , Issue.SUPPL. 1 , pp. 264
    • Boldogh, I.1    Bacsi, L.2    Agulera-Aguirre, L.3
  • 30
    • 0035966652 scopus 로고    scopus 로고
    • Cognitive effects of Colostral-Val nonapeptide in aged rats
    • Popik P, Galoch Z, Janusz M, et al. Cognitive effects of Colostral-Val nonapeptide in aged rats. Behav Brain Res 2001;118:201-8
    • (2001) Behav Brain Res , vol.118 , pp. 201-208
    • Popik, P.1    Galoch, Z.2    Janusz, M.3
  • 31
    • 0033253232 scopus 로고    scopus 로고
    • Colostrinin: A proline-rich polypeptide (PRP), complex isolated from ovine colostrum for treatment of Alzheimer's disease. A double-blind, placebo-controlled study
    • Leszek J, Inglot AD, Janusz M, et al. Colostrinin: a proline-rich polypeptide (PRP), complex isolated from ovine colostrum for treatment of Alzheimer's disease. A double-blind, placebo-controlled study. Arch Immunol Ther Exp Warsz 1999;47:377-85
    • (1999) Arch Immunol Ther Exp Warsz , vol.47 , pp. 377-385
    • Leszek, J.1    Inglot, A.D.2    Janusz, M.3
  • 32
    • 0036774346 scopus 로고    scopus 로고
    • Colostrinin praline rich polypeptide complex from ovine colostrum-a long-term study of its efficacy in Alzheimer's disease
    • Leszek J, Inglot AD, Janusz M, et al. Colostrinin praline rich polypeptide complex from ovine colostrum-a long-term study of its efficacy in Alzheimer's disease. Med Sci Monit 2002;8:PI93-6
    • (2002) Med Sci Monit , vol.8
    • Leszek, J.1    Inglot, A.D.2    Janusz, M.3
  • 33
    • 1842427909 scopus 로고    scopus 로고
    • Colostrinin (a naturally occurring, proline-rich, polypeptide mixture) in the treatment of Alzheimer's disease
    • Bilikiewicz A, Gaus W. Colostrinin (a naturally occurring, proline-rich, polypeptide mixture) in the treatment of Alzheimer's disease. J Alzheimers Dis 2004;6:17-26
    • (2004) J Alzheimers Dis , vol.6 , pp. 17-26
    • Bilikiewicz, A.1    Gaus, W.2
  • 34
    • 9944225575 scopus 로고    scopus 로고
    • A proline-rich polypeptide complex and its nonapeptide fragment inhibit nitric oxide production induced in mice
    • Zablcocka A, Janusz M, MacAlca J, Lisowski J. A proline-rich polypeptide complex and its nonapeptide fragment inhibit nitric oxide production induced in mice. Regul Pept 2005;125:35-9
    • (2005) Regul Pept , vol.125 , pp. 35-39
    • Zablcocka, A.1    Janusz, M.2    MacAlca, J.3    Lisowski, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.