메뉴 건너뛰기




Volumn 42, Issue 18, 2014, Pages 11321-11328

What makes the lac-pathway switch: Identifying the fluctuations that trigger phenotype switching in gene regulatory systems

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI PROTEIN; LAC REPRESSOR; LACI PROTEIN, E COLI; LACTOSE;

EID: 84922354418     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku839     Document Type: Article
Times cited : (19)

References (39)
  • 1
    • 1442354192 scopus 로고    scopus 로고
    • Multistability in the lactose utilization network of Escherichia coli
    • Ozbudak, E. M., Thattai, M., Lim, H. N., Shraiman, B. I. And van Oudenaarden, A. (2004) Multistability in the lactose utilization network of Escherichia coli. Nature, 427, 737-740.
    • (2004) Nature , vol.427 , pp. 737-740
    • Ozbudak, E.M.1    Thattai, M.2    Lim, H.N.3    Shraiman, B.I.4    Van Oudenaarden, A.5
  • 2
    • 84867030643 scopus 로고    scopus 로고
    • Need-based activation of ammonium uptake in Escherichia coli
    • Kim, M., Zhang, Z., Okano, H., Yan, D., Groisman, A. And Hwa, T. (2012) Need-based activation of ammonium uptake in Escherichia coli. Mol. Syst. Biol., 8, 616-626.
    • (2012) Mol. Syst. Biol. , vol.8 , pp. 616-626
    • Kim, M.1    Zhang, Z.2    Okano, H.3    Yan, D.4    Groisman, A.5    Hwa, T.6
  • 3
    • 84879728880 scopus 로고    scopus 로고
    • Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype
    • Fasani, R. A. And Savageau, M. A. (2013) Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype. Proc. Natl. Acad. Sci. U.S.A., 110, E2528-E2537.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. E2528-E2537
    • Fasani, R.A.1    Savageau, M.A.2
  • 4
    • 84862682760 scopus 로고    scopus 로고
    • Spatial positive feedback at the onset of mitosis
    • Santos, S. D., Wollman, R., Meyer, T. And Ferrell, J. E. (2012) Spatial positive feedback at the onset of mitosis. Cell, 149, 1500-1513.
    • (2012) Cell , vol.149 , pp. 1500-1513
    • Santos, S.D.1    Wollman, R.2    Meyer, T.3    Ferrell, J.E.4
  • 5
    • 41749107942 scopus 로고    scopus 로고
    • Stochasticity and cell fate
    • Losick, R. And Desplan, C. (2008) Stochasticity and cell fate. Science, 320, 65-68.
    • (2008) Science , vol.320 , pp. 65-68
    • Losick, R.1    Desplan, C.2
  • 7
    • 33645073688 scopus 로고    scopus 로고
    • Phenotypic variation in bacteria: The role of feedback regulation
    • Smits, W. K., Kuipers, O. P. And Veening, J. W. (2006) Phenotypic variation in bacteria: The role of feedback regulation. Nat. Rev. Microbiol., 4, 259-271.
    • (2006) Nat. Rev. Microbiol. , vol.4 , pp. 259-271
    • Smits, W.K.1    Kuipers, O.P.2    Veening, J.W.3
  • 10
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • Elowitz, M. B., Levine, A. J., Siggia, E. D. And Swain, P. S. (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186.
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 11
    • 18844368812 scopus 로고    scopus 로고
    • Bacterial persistence: A model of survival in changing environments
    • Kussell, E., Kishony, R., Balaban, N. Q. And Leibler, S. (2005) Bacterial persistence: A model of survival in changing environments. Genetics, 169, 1807-1814.
    • (2005) Genetics , vol.169 , pp. 1807-1814
    • Kussell, E.1    Kishony, R.2    Balaban, N.Q.3    Leibler, S.4
  • 12
  • 14
    • 34547177356 scopus 로고    scopus 로고
    • Stochastic fluctuations in metabolic pathways
    • Levine, E. And Hwa, T. (2007) Stochastic fluctuations in metabolic pathwayS. Proc. Natl. Acad. Sci. U.S.A., 104, 9224-9229.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 9224-9229
    • Levine, E.1    Hwa, T.2
  • 15
    • 0842285841 scopus 로고    scopus 로고
    • Summing up the noise in gene networks
    • Paulsson, J. (2004) Summing up the noise in gene networks. Nature, 427, 415-418.
    • (2004) Nature , vol.427 , pp. 415-418
    • Paulsson, J.1
  • 16
    • 84886768526 scopus 로고    scopus 로고
    • Stochastic fate selection in HIV-infected patients
    • Weinberger, A. D. And Weinberger, L. S. (2013) Stochastic fate selection in HIV-infected patients. Cell, 155, 497-499.
    • (2013) Cell , vol.155 , pp. 497-499
    • Weinberger, A.D.1    Weinberger, L.S.2
  • 17
    • 34547604468 scopus 로고    scopus 로고
    • Noise in gene expression determines cell fate in Bacillus subtilis
    • Maamar, H., Raj, A. And Dubnau, D. (2007) Noise in gene expression determines cell fate in Bacillus subtilis. Science, 317, 526-529.
    • (2007) Science , vol.317 , pp. 526-529
    • Maamar, H.1    Raj, A.2    Dubnau, D.3
  • 18
    • 50349086894 scopus 로고    scopus 로고
    • Timing and dynamics of single cell gene expression in the arabinose utilization system
    • Megerle, J. A., Fritz, G., Gerland, U., Jung, K. And Rädler, J. O. (2008) Timing and dynamics of single cell gene expression in the arabinose utilization system. Biophys. J., 95, 2103-2115.
    • (2008) Biophys. J. , vol.95 , pp. 2103-2115
    • Megerle, J.A.1    Fritz, G.2    Gerland, U.3    Jung, K.4    Rädler, J.O.5
  • 19
    • 54249083606 scopus 로고    scopus 로고
    • A stochastic single-molecule event triggers phenotype switching of a bacterial cell
    • Choi, P. J., Cai, L., Frieda, K. And Xie, X. S. (2008) A stochastic single-molecule event triggers phenotype switching of a bacterial cell. Science, 322, 442-446.
    • (2008) Science , vol.322 , pp. 442-446
    • Choi, P.J.1    Cai, L.2    Frieda, K.3    Xie, X.S.4
  • 20
    • 70350336588 scopus 로고    scopus 로고
    • Architecture-dependent noise discriminates functionally analogous differentiation circuits
    • Ç a?gatay, T., Turcotte, M., Elowitz, M. B., Garcia-Ojalvo, J. And Süel, G. M. (2009) Architecture-dependent noise discriminates functionally analogous differentiation circuits. Cell, 139, 512-522.
    • (2009) Cell , vol.139 , pp. 512-522
    • Çagatay, T.1    Turcotte, M.2    Elowitz, M.B.3    Garcia-Ojalvo, J.4    Süel, G.M.5
  • 21
    • 78649838304 scopus 로고    scopus 로고
    • Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene
    • Zong, C., So, L. H., Sepulveda, L. A., Skinner, S. O. And Golding, I. (2010) Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene. Mol. Syst. Biol., 6, 440-452.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 440-452
    • Zong, C.1    So, L.H.2    Sepulveda, L.A.3    Skinner, S.O.4    Golding, I.5
  • 22
    • 67650333525 scopus 로고    scopus 로고
    • Episodic selection and the maintenance of competence and natural transformation in Bacillus subtilis
    • Johnsen, P. J., Dubnau, D. And Levin, B. R. (2009) Episodic selection and the maintenance of competence and natural transformation in Bacillus subtilis. Genetics, 181, 1521-1533.
    • (2009) Genetics , vol.181 , pp. 1521-1533
    • Johnsen, P.J.1    Dubnau, D.2    Levin, B.R.3
  • 23
    • 0001389945 scopus 로고
    • Enzyme induction as an all-or-none phenomenon
    • Novick, A. And Weiner, M. (1957) Enzyme induction as an all-or-none phenomenon. PNAS, 43, 553-566.
    • (1957) PNAS , vol.43 , pp. 553-566
    • Novick, A.1    Weiner, M.2
  • 25
    • 0019867850 scopus 로고
    • The Escherichia coli lac repressor-operator interaction: Kinetic measurements and conclusions
    • Winter, R. B., Berg, O. G. And von Hippel, P. H. (1981) The Escherichia coli lac repressor-operator interaction: kinetic measurements and conclusions. Biochemistry, 20, 6961-6977.
    • (1981) Biochemistry , vol.20 , pp. 6961-6977
    • Winter, R.B.1    Berg, O.G.2    Von Hippel, P.H.3
  • 29
    • 0014966123 scopus 로고
    • Lac repressor-operator interaction.II. Effect of galactosides and other ligands
    • Riggs, A. D., Newby, R. F. And Bourgeois, S. (1970) lac repressor-operator interaction. II. Effect of galactosides and other ligands. J. Mol. Biol., 51, 303-314.
    • (1970) J. Mol. Biol. , vol.51 , pp. 303-314
    • Riggs, A.D.1    Newby, R.F.2    Bourgeois, S.3
  • 30
    • 0017330460 scopus 로고
    • Interaction of lac repressor with inducer. Kinetic and equilibrium measurements
    • Friedman, E. B., Olson, J. S. And Matthews, K. S. (1977) Interaction of lac repressor with inducer. Kinetic and equilibrium measurements. J. Mol. Biol., 111, 27-39.
    • (1977) J. Mol. Biol. , vol.111 , pp. 27-39
    • Friedman, E.B.1    Olson, J.S.2    Matthews, K.S.3
  • 31
    • 77951129749 scopus 로고    scopus 로고
    • Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch
    • Robert, L., Paul, G., Chen, Y., Taddei, F., Baigl, D. And Lindner, A. B. (2010) Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch. Mol. Syst. Biol., 6, 357-369.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 357-369
    • Robert, L.1    Paul, G.2    Chen, Y.3    Taddei, F.4    Baigl, D.5    Lindner, A.B.6
  • 32
    • 79960690479 scopus 로고    scopus 로고
    • Deterministic and stochastic population-level simulations of an artificial lac operon genetic network
    • Stamatakis, M. And Zygourakis, K. (2011) Deterministic and stochastic population-level simulations of an artificial lac operon genetic network. BMC Bioinformat., 12, 301-318.
    • (2011) BMC Bioinformat. , vol.12 , pp. 301-318
    • Stamatakis, M.1    Zygourakis, K.2
  • 33
  • 34
    • 79954598437 scopus 로고    scopus 로고
    • Design of the lac gene circuit revisited
    • Savageau, M. A. (2011) Design of the lac gene circuit revisited. Math. Biosci., 231, 19-38.
    • (2011) Math. Biosci. , vol.231 , pp. 19-38
    • Savageau, M.A.1
  • 35
  • 36
    • 30044434963 scopus 로고    scopus 로고
    • Absolute rate theories of epigenetic stability
    • Walczak, A. M., Onuchic, J. N. And Wolynes, P. G. (2005) Absolute rate theories of epigenetic stability. PNAS, 102, 18926-18931.
    • (2005) PNAS , vol.102 , pp. 18926-18931
    • Walczak, A.M.1    Onuchic, J.N.2    Wolynes, P.G.3
  • 37
  • 38
    • 0035193294 scopus 로고    scopus 로고
    • Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations
    • Kepler, T. B. And Elston, T. C. (2001) Stochasticity in transcriptional regulation: origins, consequences, and mathematical representations. Biophys. J., 81, 3116-3136.
    • (2001) Biophys. J. , vol.81 , pp. 3116-3136
    • Kepler, T.B.1    Elston, T.C.2
  • 39
    • 84896944037 scopus 로고    scopus 로고
    • Stability of bacterial toggle switches is enhanced by cell-cycle lengthening by several orders of magnitude
    • Jaruszewicz, J., Kimmel, M. And Lipniacki, T. (2014) Stability of bacterial toggle switches is enhanced by cell-cycle lengthening by several orders of magnitude. Phys. Rev. E, 89, 022710-022720.
    • (2014) Phys. Rev. e , vol.89 , pp. 022710-022720
    • Jaruszewicz, J.1    Kimmel, M.2    Lipniacki, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.