메뉴 건너뛰기




Volumn 466, Issue , 2015, Pages 189-199

Molecular mechanism of G-quadruplex unwinding helicase: Sequential and repetitive unfolding of G-quadruplex by Pif1 helicase

Author keywords

G quadruplex (G4); Genomic stability; Pif1 helicase; Single molecule fluorescence

Indexed keywords

GUANINE QUADRUPLEX; HELICASE; MONOMER; PIF1 HELICASE; UNCLASSIFIED DRUG; DNA HELICASE; FLUORESCENT DYE; PIF1 PROTEIN, S CEREVISIAE; RECOMBINANT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SINGLE STRANDED DNA;

EID: 84922336313     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140997     Document Type: Article
Times cited : (64)

References (54)
  • 1
    • 84867744921 scopus 로고    scopus 로고
    • DNA secondary structures: Stability and function of G-quadruplex structures
    • CrossRef PubMed
    • Bochman, M.L., Paeschke, K. and Zakian, V.A. (2012) DNA secondary structures: stability and function of G-quadruplex structures. Nat. Rev. Genet. 13, 770-780 CrossRef PubMed
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 770-780
    • Bochman, M.L.1    Paeschke, K.2    Zakian, V.A.3
  • 2
    • 84876862930 scopus 로고    scopus 로고
    • The G4 genome
    • CrossRef PubMed
    • Maizels, N. and Gray, L.T. (2013) The G4 genome. PLoS Genet. 9, e1003468 CrossRef PubMed
    • (2013) PLoS Genet. , vol.9 , pp. e1003468
    • Maizels, N.1    Gray, L.T.2
  • 3
    • 0001103466 scopus 로고    scopus 로고
    • Quadruplex structures in nucleic acids
    • CrossRef PubMed
    • Keniry, M.A. (2000) Quadruplex structures in nucleic acids. Biopolymers 56, 123-146 CrossRef PubMed
    • (2000) Biopolymers , vol.56 , pp. 123-146
    • Keniry, M.A.1
  • 4
    • 1042268168 scopus 로고    scopus 로고
    • G-quartets 40 years later: From 5′ -GMP to molecular biology and supramolecular chemistry
    • CrossRef
    • Davis, J.T. (2004) G-quartets 40 years later: from 5′ -GMP to molecular biology and supramolecular chemistry. Angew. Chem. Int. Ed. 43, 668-698 CrossRef
    • (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 668-698
    • Davis, J.T.1
  • 5
    • 55249109574 scopus 로고    scopus 로고
    • Stability and kinetics of G-quadruplex structures
    • CrossRef PubMed
    • Lane, A.N., Chaires, J.B., Gray, R.D. and Trent, J.O. (2008) Stability and kinetics of G-quadruplex structures. Nucleic Acids Res. 36, 5482-5515 CrossRef PubMed
    • (2008) Nucleic Acids Res. , vol.36 , pp. 5482-5515
    • Lane, A.N.1    Chaires, J.B.2    Gray, R.D.3    Trent, J.O.4
  • 6
    • 84864493844 scopus 로고    scopus 로고
    • Single-molecule study of G-quadruplex disruption using dynamic force spectroscopy
    • CrossRef PubMed
    • de Messieres, M., Chang, J.C., Brawn-Cinani, B. and La Porta, A. (2012) Single-molecule study of G-quadruplex disruption using dynamic force spectroscopy. Phys. Rev. Lett. 109, 058101 CrossRef PubMed
    • (2012) Phys. Rev. Lett. , vol.109 , pp. 058101
    • De Messieres, M.1    Chang, J.C.2    Brawn-Cinani, B.3    La Porta, A.4
  • 7
    • 84898627355 scopus 로고    scopus 로고
    • Direct and single-molecule visualization of the solution-state structures of G-hairpin and G-triplex intermediates
    • CrossRef
    • Rajendran, A., Endo, M., Hidaka, K. and Sugiyama, H. (2014) Direct and single-molecule visualization of the solution-state structures of G-hairpin and G-triplex intermediates. Angew. Chem. Int. Ed. 53, 4107-4112 CrossRef
    • (2014) Angew. Chem. Int. Ed. , vol.53 , pp. 4107-4112
    • Rajendran, A.1    Endo, M.2    Hidaka, K.3    Sugiyama, H.4
  • 8
    • 77954270742 scopus 로고    scopus 로고
    • Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single-molecule level
    • CrossRef PubMed
    • Dhakal, S., Schonhoft, J.D., Koirala, D., Yu, Z., Basu, S. and Mao, H. (2010) Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single-molecule level. J. Am. Chem. Soc. 132, 8991-8997 CrossRef PubMed
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 8991-8997
    • Dhakal, S.1    Schonhoft, J.D.2    Koirala, D.3    Yu, Z.4    Basu, S.5    Mao, H.6
  • 9
    • 30044448463 scopus 로고    scopus 로고
    • Extreme conformational diversity in human telomeric DNA
    • CrossRef PubMed
    • Lee, J., Okumus, B., Kim, D. and Ha, T. (2005) Extreme conformational diversity in human telomeric DNA. Proc. Natl. Acad. Sci. U.S.A. 102, 18938-18943 CrossRef PubMed
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 18938-18943
    • Lee, J.1    Okumus, B.2    Kim, D.3    Ha, T.4
  • 10
    • 0037142071 scopus 로고    scopus 로고
    • Crystal structure of parallel quadruplexes from human telomeric DNA
    • CrossRef PubMed
    • Parkinson, G.N., Lee, M.P.H. and Neidle, S. (2002) Crystal structure of parallel quadruplexes from human telomeric DNA. Nature 417, 876-880 CrossRef PubMed
    • (2002) Nature , vol.417 , pp. 876-880
    • Parkinson, G.N.1    Lee, M.P.H.2    Neidle, S.3
  • 11
  • 12
    • 0023788886 scopus 로고
    • Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis
    • CrossRef PubMed
    • Sen, D. and Gilbert, W. (1988) Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature 334, 364-366 CrossRef PubMed
    • (1988) Nature , vol.334 , pp. 364-366
    • Sen, D.1    Gilbert, W.2
  • 13
    • 14744275872 scopus 로고    scopus 로고
    • MutSalpha binds to and promotes synapsis of transcriptionally activated immunoglobulin switch regions
    • CrossRef PubMed
    • Larson, E.D., Duquette, M.L., Cummings, W.J., Streiff, R.J. and Maizels, N. (2005) MutSalpha binds to and promotes synapsis of transcriptionally activated immunoglobulin switch regions. Curr. Biol. 15, 470-474 CrossRef PubMed
    • (2005) Curr. Biol. , vol.15 , pp. 470-474
    • Larson, E.D.1    Duquette, M.L.2    Cummings, W.J.3    Streiff, R.J.4    Maizels, N.5
  • 14
    • 0033534467 scopus 로고    scopus 로고
    • G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, a role for G-G pairing in immunoglobulin switch recombination
    • CrossRef PubMed
    • Dempsey, L.A., Sun, H., Hanakahi, L.A. and Maizels, N. (1999) G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, a role for G-G pairing in immunoglobulin switch recombination. J. Biol. Chem. 274, 1066-1071 CrossRef PubMed
    • (1999) J. Biol. Chem. , vol.274 , pp. 1066-1071
    • Dempsey, L.A.1    Sun, H.2    Hanakahi, L.A.3    Maizels, N.4
  • 15
    • 33846928449 scopus 로고    scopus 로고
    • G-quadruplexes in promoters throughout the human genome
    • CrossRef PubMed
    • Huppert, J.L. and Balasubramanian, S. (2007) G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res. 35, 406-413 CrossRef PubMed
    • (2007) Nucleic Acids Res. , vol.35 , pp. 406-413
    • Huppert, J.L.1    Balasubramanian, S.2
  • 16
    • 70549099970 scopus 로고    scopus 로고
    • The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics
    • PubMed
    • Brooks, T.A. and Hurley, L.H. (2009) The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics. Nat. Rev. Cancer. 9, 849-861 PubMed
    • (2009) Nat. Rev. Cancer. , vol.9 , pp. 849-861
    • Brooks, T.A.1    Hurley, L.H.2
  • 17
    • 33947647457 scopus 로고    scopus 로고
    • Biophysical studies of the c-MYC NHE III1 promoter: Model quadruplex interactions with a cationic porphyrin
    • CrossRef PubMed
    • Freyer, M.W., Buscaglia, R., Kaplan, K., Cashman, D., Hurley, L.H. and Lewis, E.A. (2007) Biophysical studies of the c-MYC NHE III1 promoter: Model quadruplex interactions with a cationic porphyrin. Biophys. J. 92, 2007-2015 CrossRef PubMed
    • (2007) Biophys. J. , vol.92 , pp. 2007-2015
    • Freyer, M.W.1    Buscaglia, R.2    Kaplan, K.3    Cashman, D.4    Hurley, L.H.5    Lewis, E.A.6
  • 18
    • 31944444804 scopus 로고    scopus 로고
    • An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution
    • CrossRef PubMed
    • Dai, J., Dexheimer, T.S., Chen, D., Carver, M., Ambrus, A., Jones, R.A. and Yang, D. (2006) An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution. J. Am. Chem. Soc. 128, 1096-1098 CrossRef PubMed
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 1096-1098
    • Dai, J.1    Dexheimer, T.S.2    Chen, D.3    Carver, M.4    Ambrus, A.5    Jones, R.A.6    Yang, D.7
  • 19
    • 84877768759 scopus 로고    scopus 로고
    • G-quadruplex structures are stable and detectable in human genomic DNA
    • CrossRef PubMed
    • Lam, E.Y.N., Beraldi, D., Tannahill, D. and Balasubramanian, S. (2013) G-quadruplex structures are stable and detectable in human genomic DNA. Nat. Commun. 4, 1796 CrossRef PubMed
    • (2013) Nat. Commun. , vol.4 , pp. 1796
    • Lam, E.Y.N.1    Beraldi, D.2    Tannahill, D.3    Balasubramanian, S.4
  • 20
    • 84875464903 scopus 로고    scopus 로고
    • Quantitative visualization of DNA G-quadruplex structures in human cells
    • CrossRef PubMed
    • Biffi, G., Tannahill, D., McCafferty, J. and Balasubramanian, S. (2013) Quantitative visualization of DNA G-quadruplex structures in human cells. Nat. Chem. 5, 182-186 CrossRef PubMed
    • (2013) Nat. Chem. , vol.5 , pp. 182-186
    • Biffi, G.1    Tannahill, D.2    McCafferty, J.3    Balasubramanian, S.4
  • 21
    • 33749136403 scopus 로고    scopus 로고
    • Roles of Pif1-like helicases in the maintenance of genomic stability
    • CrossRef PubMed
    • Boul é, J.B. and Zakian, V.A. (2006) Roles of Pif1-like helicases in the maintenance of genomic stability. Nucleic Acids Res. 34, 4147-4153 CrossRef PubMed
    • (2006) Nucleic Acids Res. , vol.34 , pp. 4147-4153
    • Boulé, J.B.1    Zakian, V.A.2
  • 23
    • 10344256183 scopus 로고    scopus 로고
    • Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
    • CrossRef PubMed
    • Crabbe, L., Verdun, R.E., Haggblom, C.I. and Karlseder, J. (2004) Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 306, 1951-1953 CrossRef PubMed
    • (2004) Science , vol.306 , pp. 1951-1953
    • Crabbe, L.1    Verdun, R.E.2    Haggblom, C.I.3    Karlseder, J.4
  • 24
  • 25
    • 84861367008 scopus 로고    scopus 로고
    • The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary
    • CrossRef PubMed
    • Booy, E.P., Meier, M., Okun, N., Novakowski, S.K., Xiong, S., Stetefeld, J. and McKenna, S.A. (2012) The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary. Nucleic Acids Res. 40, 4110-4124 CrossRef PubMed
    • (2012) Nucleic Acids Res. , vol.40 , pp. 4110-4124
    • Booy, E.P.1    Meier, M.2    Okun, N.3    Novakowski, S.K.4    Xiong, S.5    Stetefeld, J.6    McKenna, S.A.7
  • 26
    • 33646100776 scopus 로고    scopus 로고
    • A conserved G4 DNA binding domain in RecQ family helicases
    • CrossRef PubMed
    • Huber, M.D., Duquette, M.L., Shiels, J.C. and Maizels, N. (2006) A conserved G4 DNA binding domain in RecQ family helicases. J. Mol. Biol. 358, 1071-1080 CrossRef PubMed
    • (2006) J. Mol. Biol. , vol.358 , pp. 1071-1080
    • Huber, M.D.1    Duquette, M.L.2    Shiels, J.C.3    Maizels, N.4
  • 27
    • 0035252650 scopus 로고    scopus 로고
    • The Pif1p subfamily of helicases: Region-specific DNA helicases?
    • CrossRef PubMed
    • Bessler, J.B., Torre, J.Z. and Zakian, V.A. (2001) The Pif1p subfamily of helicases: Region-specific DNA helicases? Trends Cell Biol. 11, 60-65 CrossRef PubMed
    • (2001) Trends Cell Biol. , vol.11 , pp. 60-65
    • Bessler, J.B.1    Torre, J.Z.2    Zakian, V.A.3
  • 28
    • 76749129611 scopus 로고    scopus 로고
    • Unwinding the functions of the Pif1 family helicases
    • CrossRef PubMed
    • Bochman, M.L., Sabouri, N. and Zakian, V.A. (2010) Unwinding the functions of the Pif1 family helicases. DNA Repair 9, 237-249 CrossRef PubMed
    • (2010) DNA Repair , vol.9 , pp. 237-249
    • Bochman, M.L.1    Sabouri, N.2    Zakian, V.A.3
  • 29
    • 84899887504 scopus 로고    scopus 로고
    • Eriodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA
    • PubMed
    • Zhou, R., Zhang, J., Bochman, M.L., Zakian, V.A. and Ha, T. (2014) Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA. eLife 3, e02190 PubMed
    • (2014) ELife , vol.3 , pp. e02190
    • Zhou, R.1    Zhang, J.2    Bochman, M.L.3    Zakian, V.A.4    Ha, T.5
  • 30
    • 44449134820 scopus 로고    scopus 로고
    • A practical guide to single-molecule FRET
    • CrossRef PubMed
    • Roy, R., Hohng, S. and Ha, T. (2008) A practical guide to single-molecule FRET. Nat. Methods 5, 507-516 CrossRef PubMed
    • (2008) Nat. Methods , vol.5 , pp. 507-516
    • Roy, R.1    Hohng, S.2    Ha, T.3
  • 31
    • 34848908787 scopus 로고    scopus 로고
    • The yeast Pif1p DNA helicase preferentially unwinds RNA-DNA substrates
    • CrossRef PubMed
    • Boul é, J.B. and Zakian, V.A. (2007) The yeast Pif1p DNA helicase preferentially unwinds RNA-DNA substrates. Nucleic Acids Res. 35, 5809-5818 CrossRef PubMed
    • (2007) Nucleic Acids Res. , vol.35 , pp. 5809-5818
    • Boulé, J.B.1    Zakian, V.A.2
  • 32
    • 0742324525 scopus 로고    scopus 로고
    • DNA-binding orientation and domain conformation of the E. Coli Rep helicase monomer bound to a partial duplex junction: Single-molecule studies of fluorescently labeled enzymes
    • CrossRef PubMed
    • Rasnik, I., Myong, S., Cheng, W., Lohman, T.M. and Ha, T. (2004) DNA-binding orientation and domain conformation of the E. coli Rep helicase monomer bound to a partial duplex junction: Single-molecule studies of fluorescently labeled enzymes. J. Mol. Biol. 336, 395-408 CrossRef PubMed
    • (2004) J. Mol. Biol. , vol.336 , pp. 395-408
    • Rasnik, I.1    Myong, S.2    Cheng, W.3    Lohman, T.M.4    Ha, T.5
  • 33
    • 1342346600 scopus 로고    scopus 로고
    • The DNA binding properties of the Escherichia coli RecQ helicase
    • CrossRef PubMed
    • Dou, S.-X., Wang, P.-Y., Xu, H.Q. and Xi, X.G. (2004) The DNA binding properties of the Escherichia coli RecQ helicase. J. Biol. Chem. 279, 6354-6363 CrossRef PubMed
    • (2004) J. Biol. Chem. , vol.279 , pp. 6354-6363
    • Dou, S.-X.1    Wang, P.-Y.2    Xu, H.Q.3    Xi, X.G.4
  • 34
    • 0035366378 scopus 로고    scopus 로고
    • Single-molecule fluorescence methods for the study of nucleic acids
    • CrossRef PubMed
    • Ha, T. (2001) Single-molecule fluorescence methods for the study of nucleic acids. Curr. Opin. Struct. Biol. 11, 287-292 CrossRef PubMed
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , pp. 287-292
    • Ha, T.1
  • 35
    • 0033556134 scopus 로고    scopus 로고
    • A DNA polymerase stop assay for G-quadruplex-interactive compounds
    • CrossRef PubMed
    • Han, H., Hurley, L.H. and Salazar, M. (1999) A DNA polymerase stop assay for G-quadruplex-interactive compounds. Nucleic Acids Res. 27, 537-542 CrossRef PubMed
    • (1999) Nucleic Acids Res. , vol.27 , pp. 537-542
    • Han, H.1    Hurley, L.H.2    Salazar, M.3
  • 36
    • 67149126812 scopus 로고    scopus 로고
    • The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo
    • CrossRef PubMed
    • Ribeyre, C., Lopes, J., Boulé, J.B., Piazza, A., Guédin, A., Zakian, V.A., Mergny, J.L. and Nicolas, A. (2009) The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo. PLoS Genet. 5, e1000475 CrossRef PubMed
    • (2009) PLoS Genet. , vol.5 , pp. e1000475
    • Ribeyre, C.1    Lopes, J.2    Boulé, J.B.3    Piazza, A.4    Guédin, A.5    Zakian, V.A.6    Mergny, J.L.7    Nicolas, A.8
  • 37
    • 79957556530 scopus 로고    scopus 로고
    • DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase
    • CrossRef PubMed
    • Paeschke, K., Capra, John A. and Zakian, Virginia A. (2011) DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell. 145, 678-691 CrossRef PubMed
    • (2011) Cell. , vol.145 , pp. 678-691
    • Paeschke, K.1    Capra John, A.2    Zakian Virginia, A.3
  • 38
    • 0027918585 scopus 로고
    • Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex
    • CrossRef PubMed
    • Wang, Y. and Patel, D.J. (1993) Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure 1, 263-282 CrossRef PubMed
    • (1993) Structure , vol.1 , pp. 263-282
    • Wang, Y.1    Patel, D.J.2
  • 40
    • 84873651708 scopus 로고    scopus 로고
    • Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences
    • CrossRef PubMed
    • Koirala, D., Ghimire, C., Bohrer, C., Sannohe, Y., Sugiyama, H. and Mao, H. (2013) Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences. J. Am. Chem. Soc. 135, 2235-2241 CrossRef PubMed
    • (2013) J. Am. Chem. Soc. , vol.135 , pp. 2235-2241
    • Koirala, D.1    Ghimire, C.2    Bohrer, C.3    Sannohe, Y.4    Sugiyama, H.5    Mao, H.6
  • 41
    • 84877028062 scopus 로고    scopus 로고
    • Direct measurement of sequential folding pathway and energy landscape of human telomeric G-quadruplex structures
    • CrossRef PubMed
    • Li, W., Hou, X.M., Wang, P.Y., Xi, X.G. and Li, M. (2013) Direct measurement of sequential folding pathway and energy landscape of human telomeric G-quadruplex structures. J. Am. Chem. Soc. 135, 6423-6426 CrossRef PubMed
    • (2013) J. Am. Chem. Soc. , vol.135 , pp. 6423-6426
    • Li, W.1    Hou, X.M.2    Wang, P.Y.3    Xi, X.G.4    Li, M.5
  • 42
    • 84868552929 scopus 로고    scopus 로고
    • POT1-TPP1 regulates telomeric overhang structural dynamics
    • CrossRef PubMed
    • Hwang, H., Buncher, N., Opresko, Patricia L. and Myong, S. (2012) POT1-TPP1 regulates telomeric overhang structural dynamics. Structure 20, 1872-1880 CrossRef PubMed
    • (2012) Structure , vol.20 , pp. 1872-1880
    • Hwang, H.1    Buncher, N.2    Opresko Patricia, L.3    Myong, S.4
  • 43
    • 78649236626 scopus 로고    scopus 로고
    • Folding pathways of human telomeric type-1 and type-2 G-quadruplex structures
    • CrossRef PubMed
    • Mashimo, T., Yagi, H., Sannohe, Y., Rajendran, A. and Sugiyama, H. (2010) Folding pathways of human telomeric type-1 and type-2 G-quadruplex structures. J. Am. Chem. Soc. 132, 14910-14918 CrossRef PubMed
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 14910-14918
    • Mashimo, T.1    Yagi, H.2    Sannohe, Y.3    Rajendran, A.4    Sugiyama, H.5
  • 44
    • 33947359032 scopus 로고    scopus 로고
    • Effect of G-tract length on the topology and stability of intramolecular DNA quadruplexes
    • CrossRef PubMed
    • Rachwal, P.A., Brown, T. and Fox, K.R. (2007) Effect of G-tract length on the topology and stability of intramolecular DNA quadruplexes. Biochemistry 46, 3036-3044 CrossRef PubMed
    • (2007) Biochemistry , vol.46 , pp. 3036-3044
    • Rachwal, P.A.1    Brown, T.2    Fox, K.R.3
  • 45
    • 35448944443 scopus 로고    scopus 로고
    • Quadruplex melting
    • CrossRef PubMed
    • Rachwal, P.A. and Fox, K.R. (2007) Quadruplex melting. Methods 43, 291-301 CrossRef PubMed
    • (2007) Methods , vol.43 , pp. 291-301
    • Rachwal, P.A.1    Fox, K.R.2
  • 46
    • 27644514163 scopus 로고    scopus 로고
    • Repetitive shuttling of a motor protein on DNA
    • CrossRef PubMed
    • Myong, S., Rasnik, I., Joo, C., Lohman, T.M. and Ha, T. (2005) Repetitive shuttling of a motor protein on DNA. Nature 437, 1321-1325 CrossRef PubMed
    • (2005) Nature , vol.437 , pp. 1321-1325
    • Myong, S.1    Rasnik, I.2    Joo, C.3    Lohman, T.M.4    Ha, T.5
  • 47
    • 80054743485 scopus 로고    scopus 로고
    • Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution
    • CrossRef
    • Jiang, Y., Douglas, N.R., Conley, N.R., Miller, E.J., Frydman, J. and Moerner, W.E. (2011) Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution. Proc. Natl. Acad. Sci. 108, 16962-16967 CrossRef
    • (2011) Proc. Natl. Acad. Sci. , vol.108 , pp. 16962-16967
    • Jiang, Y.1    Douglas, N.R.2    Conley, N.R.3    Miller, E.J.4    Frydman, J.5    Moerner, W.E.6
  • 49
    • 84877307215 scopus 로고    scopus 로고
    • Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA
    • CrossRef PubMed
    • Galletto, R. and Tomko, E.J. (2013) Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA. Nucleic Acids Res. 41, 4613-4627 CrossRef PubMed
    • (2013) Nucleic Acids Res. , vol.41 , pp. 4613-4627
    • Galletto, R.1    Tomko, E.J.2
  • 50
    • 77953192496 scopus 로고    scopus 로고
    • A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures
    • CrossRef PubMed
    • Masiero, S., Trotta, R., Pieraccini, S., De Tito, S., Perone, R., Randazzo, A. and Spada, G.P. (2010) A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures. Org. Biomol. Chem. 8, 2683-2692 CrossRef PubMed
    • (2010) Org. Biomol. Chem. , vol.8 , pp. 2683-2692
    • Masiero, S.1    Trotta, R.2    Pieraccini, S.3    De Tito, S.4    Perone, R.5    Randazzo, A.6    Spada, G.P.7
  • 52
    • 84875896821 scopus 로고    scopus 로고
    • Circular dichroism of quadruplex structures
    • Chaires, J.B. and Graves, D. Springer, Heidelberg
    • Randazzo, A., Spada, G. and da Silva, M. (2013) Circular dichroism of quadruplex structures. In Quadruplex nucleic acids (Chaires, J.B. and Graves, D., eds), pp. 67-86, Springer, Heidelberg
    • (2013) Quadruplex Nucleic Acids , pp. 67-86
    • Randazzo, A.1    Spada, G.2    Da Silva, M.3
  • 53
    • 84891400223 scopus 로고    scopus 로고
    • Existence and consequences of G-quadruplex structures in DNA
    • CrossRef PubMed
    • Murat, P. and Balasubramanian, S. (2014) Existence and consequences of G-quadruplex structures in DNA. Curr. Opin. Genet. Dev. 25, 22-29 CrossRef PubMed
    • (2014) Curr. Opin. Genet. Dev. , vol.25 , pp. 22-29
    • Murat, P.1    Balasubramanian, S.2
  • 54
    • 66349125451 scopus 로고    scopus 로고
    • Predicting and understanding the stability of G-quadruplexes
    • CrossRef PubMed
    • Stegle, O., Payet, L., Mergny, J.-L., MacKay, D.J.C. and Huppert, J.L. (2009) Predicting and understanding the stability of G-quadruplexes. Bioinformatics 25, i374-i1382 CrossRef PubMed
    • (2009) Bioinformatics , vol.25 , pp. i374-i1382
    • Stegle, O.1    Payet, L.2    Mergny, J.-L.3    MacKay, D.J.C.4    Huppert, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.