Delayed pituitary adenylate cyclase-activating polypeptide delivery after brain stroke improves functional recovery by inducing M2 microglia/macrophage polarization

Stroke

Volumn 46, Issue 2, 2015, Pages 520-528

  Brifault, Coralie ^a,b,c   Gras, Marjorie ^a,b,c   Liot, Donovan ^a,b,c   May, Victor ^d   Vaudry, David ^a,b,c   Wurtz, Olivier ^a,b,c  

^a INSERM   (France)

^b UNIVERSITY OF ROUEN   (France)

^c UNIVERSITÉ DE ROUEN   (France)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

inflammation; microglia; pituitary adenylate cyclase activating polypeptide; stroke

Indexed keywords

ARGINASE 1; CCAAT ENHANCER BINDING PROTEIN BETA; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOTCH RECEPTOR; ADCYAP1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOINFORMATICS; BRAIN FUNCTION; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CORRELATIONAL STUDY; IMMUNOMODULATION; IN VIVO STUDY; MACROPHAGE; MALE; MICROGLIA; MORPHOMETRICS; MOUSE; NEUROMODULATION; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; TRANSCRIPTOMICS; 129 MOUSE; ANIMAL; BRAIN; CELL POLARITY; CONVALESCENCE; DRUG DELIVERY SYSTEM; DRUG EFFECTS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; PHYSIOLOGY; PROCEDURES; STEM CELL TRANSPLANTATION; STROKE; TIME; TRANSGENIC MOUSE;

ANIMALS; BRAIN; CELL POLARITY; DRUG DELIVERY SYSTEMS; INJECTIONS, INTRAVENTRICULAR; MACROPHAGES; MALE; MICE; MICE, 129 STRAIN; MICE, TRANSGENIC; MICROGLIA; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECOVERY OF FUNCTION; STEM CELL TRANSPLANTATION; STROKE; TIME FACTORS;

EID: 84922321919     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.006864     Document Type: Article

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