Ethanol and normobaric oxygen: Novel approach in modulating pyruvate dehydrogenase complex after severe transient and permanent ischemic stroke

Stroke

Volumn 46, Issue 2, 2015, Pages 492-499

  Geng, Xiaokun ^a,c   Elmadhoun, Omar ^c   Peng, Changya ^c   Ji, Xunming ^a,b,d   Hafeez, Adam ^c   Liu, Zongjian ^a   Du, Huishan ^a   Rafols, Jose A ^c   Ding, Yuchuan ^a,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

Author keywords

EtOH; ischemia reperfusion injury; metabolism; pyruvate dehydrogeanse complex; pyruvate dehydrogenase kinase; pyruvate dehydrogenase phosphatase; reactive oxygen species

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ALCOHOL; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE PHOSPHATASE; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; NEUROPROTECTIVE AGENT;

ADULT; AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN METABOLISM; CONTROLLED STUDY; DOSE RESPONSE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN TENSION; OXYGEN THERAPY; PRIORITY JOURNAL; RAT; REPERFUSION; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; ISCHEMIC ATTACK, TRANSIENT; PHYSIOLOGY; PROCEDURES; SEVERITY OF ILLNESS INDEX; SPRAGUE DAWLEY RAT; STROKE;

ANIMALS; ETHANOL; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; OXYGEN INHALATION THERAPY; PYRUVATE DEHYDROGENASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; SEVERITY OF ILLNESS INDEX; STROKE;

EID: 84922319832     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.006994     Document Type: Article

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