Synergetic neuroprotection of normobaric oxygenation and ethanol in ischemic stroke through improved oxidative mechanism

Stroke

Volumn 44, Issue 5, 2013, Pages 1418-1425

  Geng, Xiaokun ^a,c   Fu, Paul ^c   Ji, Xunming ^a,b   Peng, Changya ^c   Fredrickson, Vance ^c   Sy, Christopher ^c   Meng, Ran ^a   Ling, Feng ^b   Du, Huishan ^a   Tan, Xiaomu ^a   Hüttemann, Maik ^c   Guthikonda, Murali ^c   Ding, Yuchuan ^a,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

aerobic glucose metabolism; ATP; combination therapy; ischemia reperfusion; reactive oxygen species

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ALCOHOL; PYRUVATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

AEROBIC METABOLISM; ALCOHOL BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN TISSUE; CELL METABOLISM; CONTROLLED STUDY; ENERGY BALANCE; ENERGY YIELD; ENZYME ACTIVITY; GLUCOSE METABOLISM; MALE; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY OCCLUSION; MONOTHERAPY; MOTOR PERFORMANCE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONCENTRATION; OXYGEN TENSION; OXYGENATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION; REPERFUSION INJURY; WESTERN BLOTTING;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN; BRAIN ISCHEMIA; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; ETHANOL; NEUROPROTECTIVE AGENTS; OXYGEN INHALATION THERAPY; RATS; REACTIVE OXYGEN SPECIES; STROKE; TREATMENT OUTCOME;

EID: 84876822612     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.000315     Document Type: Article

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