Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke

Neurology

Volumn 58, Issue 6, 2002, Pages 945-952

  Singhal, Aneesh B ^a   Dijkhuizen, Rick M ^a   Rosen, Bruce R ^a   Lo, Eng H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DIFFUSION; HYPERBARIC OXYGEN; HYPEROXIA; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN THERAPY; PRIORITY JOURNAL; RAT; REPERFUSION; STROKE;

EID: 0037177102     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.58.6.945     Document Type: Article

References (42)

1. Hyperbaric oxygen decreases infarct size and behavioral deficit after transient focal cerebral ischemia in rats
2. Hyperbaric oxygen reduces infarct volume in rats by increasing oxygen supply to the ischemic periphery
3. Hyperbaric oxygen in the treatment of acute ischemic stroke. A double-blind pilot study
4. Therapeutic tie effects of hyperbaric oxygenation on acute focal cerebral ischemia in rats
5. Hyperbaric oxygen and cerebral infarction in the gerbil
6. Results of hyperbaric oxygen therapy during temporary middle cerebral artery occlusion in unanesthetized cats
7. Hyperbaric oxygenation as an adjunct therapy in strokes due to thrombosis. A review of 122 patients
8. The use of hyperbaric oxygenation in the treatment of cerebral ischemia and infarction
9. A pilot study of hyperbaric oxygen in the treatment of human stroke
10. Effects of hyperbaric oxygen on neurologic outcome for cerebral ischemia in rats
11. Effects of normobaric hyperoxia in a rat model of transient focal cerebral ischemia and reperfusion
12. Hypoxia, hyperoxia, ischemia, and brain necrosis
13. Hyperoxia during ischemia and reperfusion in transient MCA occlusion
14. Early detection of regional cerebral ischemia in cats: Comparison of diffusion- and T2-weighted MRI and spectroscopy
15. Diffusionweighted magnetic resonance imaging of acute focal cerebral ischemia: Comparison of signal intensity with changes in brain water and Na+,K(+)-ATPase activity
16. Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI
17. Pharmacologic reversal of acute changes in diffusion-weighted magnetic resonance imaging in focal cerebral ischemia
18. Reversible middle cerebral artery occlusion without craniectomy in rats
19. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis
20. The role of spreading depression in focal ischemia evaluated by diffusion mapping
21. Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
22. Hyperbaric oxygen decreases COX-2 expression and infarction in MCAO rats
23. Hyperbaric oxygen treatment provides histopathological protection following fluid percussion brain injury and secondary hypoxia
24. Effects of hyperbaric oxygenation therapy on cerebral metabolism and intracranial pressure in severely brain injured patients
25. Dynamics of cerebral tissue injury and perfusion after temporary hypoxia-ischemia in the rat: Evidence for region-specific sensitivity and delayed damage
26. Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat
27. Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats: Correlation with histopathology
28. Should stroke victims routinely receive supplemental oxygen? A quasi-randomized controlled trial
29. Lipid peroxidation in vivo induced by reversible global ischemia in rat brain
30. Breathing 100% oxygen after global brain ischemia in Mongolian Gerbils results in increased lipid peroxidation and increased mortality
31. Oxygen radicals in cerebral ischemia
32. An obligate role for oxygen in the early stages of glutamate-induced, delayed neuronal death
33. Free radical production and ischemic brain damage: Influence of postischemic oxygen tension
34. Effects of high atmospheric pressure and oxygen on middle cerebral blood flow velocity in humans measured by transcranial Doppler
35. The effect of hyperoxia on cerebral blood flow: A study in healthy volunteers using magnetic resonance phase-contrast angiography
36. Cerebral vasomotor responsiveness during 100% oxygen inhalation in cerebral ischemia
37. NMR imaging of the apparent diffusion coefficient (ADC) for the evaluation of metabolic suppression and recovery after prolonged cerebral ischemia
38. Increased inspired oxygen concentration as a factor in improved brain tissue oxygenation and tissue lactate levels after severe human head injury
39. Oxygen transport in the rat brain cortex at normobaric hyperoxia
40. Effect of hyperoxia, hypercapnia, and hypoxia on cerebral interstitial oxygen tension and cerebral blood flow
41. Periinfarct depolarizations