Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 4, 2015, Pages 855-860

  Guo, Chuanxin ^a   Kawamoto, Yusuke ^a   Asamitsu, Sefan ^a   Sawatani, Yoshito ^a   Hashiya, Kaori ^a   Bando, Toshikazu ^a   Sugiyama, Hiroshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

DNA minor groove binder; Melting temperature; Pyrrole imidazole polyamide; Surface plasmon resonance; Telomeres

Indexed keywords

1 METHYLIMIDAZOLE; 1 METHYLPYRROLE; ADENINE; DNA; GUANINE; POLYAMIDE; THYMINE; IMIDAZOLE; IMIDAZOLE DERIVATIVE; NYLON; PYRROLE DERIVATIVE;

ARTICLE; BINDING AFFINITY; DNA BINDING; DNA HAIRPIN; DNA SEQUENCE; DNA SYNTHESIS; HUMAN; MELTING POINT; SURFACE PLASMON RESONANCE; TELOMERE; TEMPERATURE MEASUREMENT; CHEMISTRY; CONFORMATION; METABOLISM; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; DNA; HUMANS; IMIDAZOLES; NUCLEIC ACID CONFORMATION; NYLONS; PYRROLES; SURFACE PLASMON RESONANCE; TELOMERE;

EID: 84922319198     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.12.025     Document Type: Article

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