-
1
-
-
84885214146
-
An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide)
-
Korpal M, et al. (2013) An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide). Cancer Disc 3(9):1030-1043.
-
(2013)
Cancer Disc
, vol.3
, Issue.9
, pp. 1030-1043
-
-
Korpal, M.1
-
2
-
-
84885468685
-
Androgen receptors in hormone-dependent and castration-resistant prostate cancer
-
Shafi AA, Yen AE, Weigel NL (2013) Androgen receptors in hormone-dependent and castration-resistant prostate cancer. Pharmacol Ther 140(3):223-238.
-
(2013)
Pharmacol Ther
, vol.140
, Issue.3
, pp. 223-238
-
-
Shafi, A.A.1
Yen, A.E.2
Weigel, N.L.3
-
3
-
-
84900373381
-
Targeting the androgen receptor pathway in castration-resistant prostate cancer: Progresses and prospects
-
Ferraldeschi R, Welti J, Luo J, Attard G, de Bono JS (2014) Targeting the androgen receptor pathway in castration-resistant prostate cancer: Progresses and prospects. Oncogene, 10.1038/onc.2014.115.
-
(2014)
Oncogene
-
-
Ferraldeschi, R.1
Welti, J.2
Luo, J.3
Attard, G.4
De Bono, J.S.5
-
4
-
-
58049196759
-
Mechanisms mediating androgen receptor reactivation after castration
-
Yuan X, Balk SP (2009) Mechanisms mediating androgen receptor reactivation after castration. Urol Oncol 27(1):36-41.
-
(2009)
Urol Oncol
, vol.27
, Issue.1
, pp. 36-41
-
-
Yuan, X.1
Balk, S.P.2
-
5
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen CD, et al. (2004) Molecular determinants of resistance to antiandrogen therapy. Nat Med 10(1):33-39.
-
(2004)
Nat Med
, vol.10
, Issue.1
, pp. 33-39
-
-
Chen, C.D.1
-
6
-
-
84885210324
-
A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509
-
Joseph JD, et al. (2013) A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509. Cancer Disc 3(9):1020-1029.
-
(2013)
Cancer Disc
, vol.3
, Issue.9
, pp. 1020-1029
-
-
Joseph, J.D.1
-
7
-
-
18144404148
-
Physiological role of collagen XVIII and endostatin
-
Marneros AG, Olsen BR (2005) Physiological role of collagen XVIII and endostatin. FASEB J 19(7):716-728.
-
(2005)
FASEB J
, vol.19
, Issue.7
, pp. 716-728
-
-
Marneros, A.G.1
Olsen, B.R.2
-
8
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, et al. (1997) Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell 88(2):277-285.
-
(1997)
Cell
, vol.88
, Issue.2
, pp. 277-285
-
-
O'Reilly, M.S.1
-
9
-
-
12844268491
-
Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo
-
Skovseth DK, Veuger MJ, Sorensen DR, De Angelis PM, Haraldsen G (2005) Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo. Blood 105(3):1044-1051.
-
(2005)
Blood
, vol.105
, Issue.3
, pp. 1044-1051
-
-
Skovseth, D.K.1
Veuger, M.J.2
Sorensen, D.R.3
De Angelis, P.M.4
Haraldsen, G.5
-
10
-
-
0037440123
-
Phase I pharmacokinetic and pharmacodynamic study of recombinant human endostatin in patients with advanced solid tumors
-
Thomas JP, et al. (2003) Phase I pharmacokinetic and pharmacodynamic study of recombinant human endostatin in patients with advanced solid tumors. J Clin Oncol 21(2):223-231.
-
(2003)
J Clin Oncol
, vol.21
, Issue.2
, pp. 223-231
-
-
Thomas, J.P.1
-
11
-
-
69449104191
-
Unraveling the mysteries of endostatin
-
Fu Y, Tang H, Huang Y, Song N, Luo Y (2009) Unraveling the mysteries of endostatin. IUBMB Life 61(6):613-626.
-
(2009)
IUBMB Life
, vol.61
, Issue.6
, pp. 613-626
-
-
Fu, Y.1
Tang, H.2
Huang, Y.3
Song, N.4
Luo, Y.5
-
12
-
-
0035887379
-
Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model
-
Kisker O, et al. (2001) Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res 61(20):7669-7674.
-
(2001)
Cancer Res
, vol.61
, Issue.20
, pp. 7669-7674
-
-
Kisker, O.1
-
13
-
-
0034712958
-
Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases
-
Sauter BV, Martinet O, Zhang WJ, Mandeli J, Woo SL (2000) Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases. Proc Natl Acad Sci USA 97(9):4802-4807.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.9
, pp. 4802-4807
-
-
Sauter, B.V.1
Martinet, O.2
Zhang, W.J.3
Mandeli, J.4
Woo, S.L.5
-
14
-
-
34547891037
-
Transcriptional network governing the angiogenic switch in human pancreatic cancer
-
Abdollahi A, et al. (2007) Transcriptional network governing the angiogenic switch in human pancreatic cancer. Proc Natl Acad Sci USA 104(31):12890-12895.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.31
, pp. 12890-12895
-
-
Abdollahi, A.1
-
15
-
-
34250843284
-
Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model
-
Isayeva T, Chanda D, Kallman L, Eltoum IE, Ponnazhagan S (2007) Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model. Cancer Res 67(12):5789-5797.
-
(2007)
Cancer Res
, vol.67
, Issue.12
, pp. 5789-5797
-
-
Isayeva, T.1
Chanda, D.2
Kallman, L.3
Eltoum, I.E.4
Ponnazhagan, S.5
-
16
-
-
84908027614
-
Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver
-
Chang C, Lee SO, Yeh S, Chang TM (2014) Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver. Oncogene 33(25):3225-3234.
-
(2014)
Oncogene
, vol.33
, Issue.25
, pp. 3225-3234
-
-
Chang, C.1
Lee, S.O.2
Yeh, S.3
Chang, T.M.4
-
17
-
-
8344226282
-
Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
-
He B, et al. (2004) Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance. Mol Cell 16(3):425-438.
-
(2004)
Mol Cell
, vol.16
, Issue.3
, pp. 425-438
-
-
He, B.1
-
18
-
-
0036351145
-
The NH(2)-terminal and carboxyl-terminal interaction in the human androgen receptor
-
He B, Wilson EM (2002) The NH(2)-terminal and carboxyl-terminal interaction in the human androgen receptor. Mol Genet Metab 75(4):293-298.
-
(2002)
Mol Genet Metab
, vol.75
, Issue.4
, pp. 293-298
-
-
He, B.1
Wilson, E.M.2
-
19
-
-
13444304134
-
Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction
-
Bai S, He B, Wilson EM (2005) Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction. Mol Cell Biol 25(4):1238-1257.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.4
, pp. 1238-1257
-
-
Bai, S.1
He, B.2
Wilson, E.M.3
-
20
-
-
19344376991
-
Recognition and accommodation at the androgen receptor coactivator binding interface
-
Hur E, et al. (2004) Recognition and accommodation at the androgen receptor coactivator binding interface. PLoS Biol 2(9):E274.
-
(2004)
PLoS Biol
, vol.2
, Issue.9
, pp. E274
-
-
Hur, E.1
-
21
-
-
0037371767
-
Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs
-
He B, Wilson EM (2003) Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs. Mol Cell Biol 23(6):2135-2150.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.6
, pp. 2135-2150
-
-
He, B.1
Wilson, E.M.2
-
22
-
-
0032536859
-
Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution
-
Hohenester E, Sasaki T, Olsen BR, Timpl R (1998) Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution. EMBO J 17(6):1656-1664.
-
(1998)
EMBO J
, vol.17
, Issue.6
, pp. 1656-1664
-
-
Hohenester, E.1
Sasaki, T.2
Olsen, B.R.3
Timpl, R.4
-
23
-
-
13144268552
-
Zinc-dependent dimers observed in crystals of human endostatin
-
Ding YH, et al. (1998) Zinc-dependent dimers observed in crystals of human endostatin. Proc Natl Acad Sci USA 95(18):10443-10448.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.18
, pp. 10443-10448
-
-
Ding, Y.H.1
-
24
-
-
46549085970
-
Refolding of endostatin from inclusion bodies using high hydrostatic pressure
-
Chura-Chambi RM, Genova LA, Affonso R, Morganti L (2008) Refolding of endostatin from inclusion bodies using high hydrostatic pressure. Anal Biochem 379(1):32-39.
-
(2008)
Anal Biochem
, vol.379
, Issue.1
, pp. 32-39
-
-
Chura-Chambi, R.M.1
Genova, L.A.2
Affonso, R.3
Morganti, L.4
-
25
-
-
0035863320
-
Soluble recombinant endostatin purified from Escherichia coli: Antiangiogenic activity and antitumor effect
-
Huang X, et al. (2001) Soluble recombinant endostatin purified from Escherichia coli: Antiangiogenic activity and antitumor effect. Cancer Res 61(2):478-481.
-
(2001)
Cancer Res
, vol.61
, Issue.2
, pp. 478-481
-
-
Huang, X.1
-
26
-
-
0033597130
-
Endostatin induces endothelial cell apoptosis
-
Dhanabal M, et al. (1999) Endostatin induces endothelial cell apoptosis. J Biol Chem 274(17):11721-11726.
-
(1999)
J Biol Chem
, vol.274
, Issue.17
, pp. 11721-11726
-
-
Dhanabal, M.1
-
27
-
-
0036790094
-
Endostatin associates with integrin alpha5beta1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells
-
Wickström SA, Alitalo K, Keski-Oja J (2002) Endostatin associates with integrin alpha5beta1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells. Cancer Res 62(19):5580-5589.
-
(2002)
Cancer Res
, vol.62
, Issue.19
, pp. 5580-5589
-
-
Wickström, S.A.1
Alitalo, K.2
Keski-Oja, J.3
-
28
-
-
67449152199
-
Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor status
-
Isayeva T, Moore LD, Chanda D, Chen D, Ponnazhagan S (2009) Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor status. Prostate 69(10):1055-1066.
-
(2009)
Prostate
, vol.69
, Issue.10
, pp. 1055-1066
-
-
Isayeva, T.1
Moore, L.D.2
Chanda, D.3
Chen, D.4
Ponnazhagan, S.5
-
29
-
-
0141676097
-
Endocrine mechanisms of disease: Expression and degradation of androgen receptor: Mechanism and clinical implication
-
Lee DK, Chang C (2003) Endocrine mechanisms of disease: Expression and degradation of androgen receptor: Mechanism and clinical implication. J Clin Endocrinol Metab 88(9):4043-4054.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.9
, pp. 4043-4054
-
-
Lee, D.K.1
Chang, C.2
-
30
-
-
84879067087
-
Overcoming mutation-based resistance to antiandrogens with rational drug design
-
Balbas MD, et al. (2013) Overcoming mutation-based resistance to antiandrogens with rational drug design. eLife 2:e00499.
-
(2013)
ELife
, vol.2
, pp. e00499
-
-
Balbas, M.D.1
-
31
-
-
1542327635
-
Acid-induced unfolding mechanism of recombinant human endostatin
-
Li B, Wu X, Zhou H, Chen Q, Luo Y (2004) Acid-induced unfolding mechanism of recombinant human endostatin. Biochemistry 43(9):2550-2557.
-
(2004)
Biochemistry
, vol.43
, Issue.9
, pp. 2550-2557
-
-
Li, B.1
Wu, X.2
Zhou, H.3
Chen, Q.4
Luo, Y.5
-
32
-
-
15744404413
-
Contributions of disulfide bonds in a nested pattern to the structure, stability, and biological functions of endostatin
-
Zhou H, Wang W, Luo Y (2005) Contributions of disulfide bonds in a nested pattern to the structure, stability, and biological functions of endostatin. J Biol Chem 280(12): 11303-11312.
-
(2005)
J Biol Chem
, vol.280
, Issue.12
, pp. 11303-11312
-
-
Zhou, H.1
Wang, W.2
Luo, Y.3
-
33
-
-
74749102446
-
Androgen receptor and androgen-dependent gene expression in lung
-
Mikkonen L, Pihlajamaa P, Sahu B, Zhang FP, Jänne OA (2010) Androgen receptor and androgen-dependent gene expression in lung. Mol Cell Endocrinol 317(1-2):14-24.
-
(2010)
Mol Cell Endocrinol
, vol.317
, Issue.1-2
, pp. 14-24
-
-
Mikkonen, L.1
Pihlajamaa, P.2
Sahu, B.3
Zhang, F.P.4
Jänne, O.A.5
-
34
-
-
58149310646
-
A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells
-
Recchia AG, et al. (2009) A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells. Int J Biochem Cell Biol 41(3): 603-614.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, Issue.3
, pp. 603-614
-
-
Recchia, A.G.1
-
35
-
-
84890078624
-
Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade
-
Arora VK, et al. (2013) Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade. Cell 155(6):1309-1322.
-
(2013)
Cell
, vol.155
, Issue.6
, pp. 1309-1322
-
-
Arora, V.K.1
-
36
-
-
55049086227
-
The contribution of different androgen receptor domains to receptor dimerization and signaling
-
Centenera MM, Harris JM, Tilley WD, Butler LM (2008) The contribution of different androgen receptor domains to receptor dimerization and signaling. Mol Endocrinol 22(11):2373-2382.
-
(2008)
Mol Endocrinol
, vol.22
, Issue.11
, pp. 2373-2382
-
-
Centenera, M.M.1
Harris, J.M.2
Tilley, W.D.3
Butler, L.M.4
|