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Volumn 55, Issue 11, 2014, Pages 7321-7331

Mechanisms of endothelial to mesenchymal transition in the retina in diabetes

Author keywords

Diabetes; Endothelial mesenchymal transition; MiR 200b; P300; Retina; TGF

Indexed keywords

4 [4 (1, 3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL] BENZAMIDE; CALVASCULIN; CD31 ANTIGEN; COLLAGEN TYPE 1; E1A ASSOCIATED P300 PROTEIN; FIBRONECTIN; MICRORNA 200B; SMAD2 PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; TRANSGELIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; VIMENTIN; EP300 PROTEIN, MOUSE; MESSENGER RNA; MICRORNA; MIRN200 MICRORNA, MOUSE;

EID: 84922295429     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-15167     Document Type: Article
Times cited : (109)

References (47)
  • 2
    • 84862182412 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: Effects on angiogenesis, vascular remodeling, and wound healing
    • Kolluru GK, Bir SC, Kevil CG. Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing. Int J Vasc Med. 2012;2012:918267.
    • (2012) Int J Vasc Med , pp. 2012
    • Kolluru, G.K.1    Bir, S.C.2    Kevil, C.G.3
  • 4
    • 57749177096 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: Roles of hyperglycemia, impaired insulin signaling and obesity
    • Bakker W, Eringa EC, Sipkema P, van Hinsbergh VW. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 2009; 335:165–189.
    • (2009) Cell Tissue Res , vol.335 , pp. 165-189
    • Bakker, W.1    Eringa, E.C.2    Sipkema, P.3    van Hinsbergh, V.W.4
  • 5
    • 80755152827 scopus 로고    scopus 로고
    • McArthur K, et al. MiR-146a-Mediated extracellular matrix protein production in chronic diabetes complications
    • Feng B, Chen S, McArthur K, et al. miR-146a-Mediated extracellular matrix protein production in chronic diabetes complications. Diabetes. 2011;60:2975–2984.
    • (2011) Diabetes , vol.60 , pp. 2975-2984
    • Feng, B.1    Chen, S.2
  • 6
    • 33744782901 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction in diabetic cardiomyopa-thy: Pathogenesis and potential treatment targets
    • Farhangkhoee H, Khan ZA, Kaur H, Xin X, Chen S, Chakrabarti S. Vascular endothelial dysfunction in diabetic cardiomyopa-thy: pathogenesis and potential treatment targets. Pharmacol Ther. 2006;111:384–399.
    • (2006) Pharmacol Ther , vol.111 , pp. 384-399
    • Farhangkhoee, H.1    Khan, Z.A.2    Kaur, H.3    Xin, X.4    Chen, S.5    Chakrabarti, S.6
  • 7
    • 34250174504 scopus 로고    scopus 로고
    • The role of epithelial-mesenchymal transition in cancer pathology
    • Guarino M, Rubino B, Ballabio G. The role of epithelial-mesenchymal transition in cancer pathology. Pathology. 2007; 39:305–318.
    • (2007) Pathology , vol.39 , pp. 305-318
    • Guarino, M.1    Rubino, B.2    Ballabio, G.3
  • 8
    • 84872694870 scopus 로고    scopus 로고
    • Molecular mechanisms of endothelial to mesenchymal cell transition (EndoMT) in experimentally induced fibrotic diseases
    • Piera-Velazquez S, Jimenez SA. Molecular mechanisms of endothelial to mesenchymal cell transition (EndoMT) in experimentally induced fibrotic diseases. Fibrogenesis Tissue Repair Suppl. 2012;1:S7.
    • (2012) Fibrogenesis Tissue Repair , vol.1 , pp. S7
    • Piera-Velazquez, S.1    Jimenez, S.A.2
  • 9
    • 84866506325 scopus 로고    scopus 로고
    • High glucose mediates endothelial-to-chondrocyte transition in human aortic endothelial cells
    • Tang R, Gao M, Wu M, Liu H, Zhang X, Liu B. High glucose mediates endothelial-to-chondrocyte transition in human aortic endothelial cells. Cardiovasc Diabetol. 2012;11:113.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 113
    • Tang, R.1    Gao, M.2    Wu, M.3    Liu, H.4    Zhang, X.5    Liu, B.6
  • 10
    • 84880412454 scopus 로고    scopus 로고
    • Roles of TGF-b signals in endothelial-mesenchymal transition during cardiac fibrosis
    • Yoshimatsu Y, Watabe T. Roles of TGF-b signals in endothelial-mesenchymal transition during cardiac fibrosis. Int J Inflam. 2011;2011:724080.
    • (2011) Int J Inflam , pp. 2011
    • Yoshimatsu, Y.1    Watabe, T.2
  • 11
    • 73549092294 scopus 로고    scopus 로고
    • Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice
    • Li J, Qu X, Bertram JF. Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am J Pathol. 2009;175:1380–1388.
    • (2009) Am J Pathol , vol.175 , pp. 1380-1388
    • Li, J.1    Qu, X.2    Bertram, J.F.3
  • 12
    • 77953364227 scopus 로고    scopus 로고
    • Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition
    • Widyantoro B, Emoto N, Nakayama K, et al. Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition. Circulation. 2010;121:2407–2418.
    • (2010) Circulation , vol.121 , pp. 2407-2418
    • Widyantoro, B.1    Emoto, N.2    Nakayama, K.3
  • 13
    • 84857824476 scopus 로고    scopus 로고
    • Regulation of endothelial cell plasticity by TGF-b
    • van Meeteren LA, ten Dijke P. Regulation of endothelial cell plasticity by TGF-b. Cell Tissue Res. 2012;347:177–186.
    • (2012) Cell Tissue Res , vol.347 , pp. 177-186
    • Van Meeteren, L.A.1    Ten Dijke, P.2
  • 14
    • 0029061401 scopus 로고
    • Molecular regulation of atrioventricular valvuloseptal morphogenesis
    • Eisenberg LM, Markwald RR. 1995;Molecular regulation of atrioventricular valvuloseptal morphogenesis. Circ Res. 77:1–6.
    • (1995) Circ Res , vol.77 , pp. 1-6
    • Eisenberg, L.M.1    Markwald, R.R.2
  • 16
    • 79960217559 scopus 로고    scopus 로고
    • Transforming growth factor-b2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-indepen-dent signaling
    • Medici D, Potenta S, Kalluri R. Transforming growth factor-b2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-indepen-dent signaling. Biochem J. 2011; 437:515–520.
    • (2011) Biochem J , vol.437 , pp. 515-520
    • Medici, D.1    Potenta, S.2    Kalluri, R.3
  • 17
    • 56349114070 scopus 로고    scopus 로고
    • Snail is required for TGFb-induced endothelial mesenchymal transition of embryonic stem cell-derived endothelial cells
    • Kokudo T, Suzuki Y, Yoshimatsu Y, Yamazaki T, Watabe T, Miyazono K. Snail is required for TGFb-induced endothelial mesenchymal transition of embryonic stem cell-derived endothelial cells. J Cell Sci. 2008;121:3317–3324.
    • (2008) J Cell Sci , vol.121 , pp. 3317-3324
    • Kokudo, T.1    Suzuki, Y.2    Yoshimatsu, Y.3    Yamazaki, T.4    Watabe, T.5    Miyazono, K.6
  • 18
    • 84883739507 scopus 로고    scopus 로고
    • Snail as a potential target molecule in cardiac fibrosis: Paracrine action of endothelial
    • Lee SW, Won JY, Kim WJ, et al. Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis. Mol Ther. 2013;21:1767–1777.
    • (2013) Mol Ther , vol.21 , pp. 1767-1777
    • Lee, S.W.1    Won, J.Y.2    Kim, W.J.3
  • 19
    • 84896720813 scopus 로고    scopus 로고
    • Targeting epithelial-to-mesenchymal transition with met inhibitors reverts chemore-sistance in small cell lung cancer
    • Canadas I, Rojo F, Taus A, et al. Targeting epithelial-to-mesenchymal transition with met inhibitors reverts chemore-sistance in small cell lung cancer. Clin Cancer Res. 2014;20: 938–950.
    • (2014) Clin Cancer Res , vol.20 , pp. 938-950
    • Canadas, I.1    Rojo, F.2    Taus, A.3
  • 20
    • 58849144604 scopus 로고    scopus 로고
    • Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter
    • Lopez D, Niu G, Huber P, Carter WB. Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter. Arch Biochem Biophys. 2009;482:77–82.
    • (2009) Arch Biochem Biophys , vol.482 , pp. 77-82
    • Lopez, D.1    Niu, G.2    Huber, P.3    Carter, W.B.4
  • 21
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • Moody SE, Perez D, Pan TC, et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell. 2005;8:197–209.
    • (2005) Cancer Cell , vol.8 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3
  • 22
    • 80051519486 scopus 로고    scopus 로고
    • Snail involves in the transforming growth factor b1-mediated epithelial-mesenchy-mal transition of retinal pigment epithelial cells
    • Li H, Wang H, Wang F, Gu Q, Xu X. Snail involves in the transforming growth factor b1-mediated epithelial-mesenchy-mal transition of retinal pigment epithelial cells. PLoS One. 2011;6:e23322.
    • (2011) Plos One , pp. 6
    • Li, H.1    Wang, H.2    Wang, F.3    Gu, Q.4    Xu, X.5
  • 23
    • 58149316623 scopus 로고    scopus 로고
    • Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3
    • Medici D, Hay ED, Olsen BR. Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell. 2008;19:4875–4887.
    • (2008) Mol Biol Cell , vol.19 , pp. 4875-4887
    • Medici, D.1    Hay, E.D.2    Olsen, B.R.3
  • 24
    • 84857111170 scopus 로고    scopus 로고
    • Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT
    • Ghosh AK, Nagpal V, Covington JW, Michaels MA, Vaughan DE. Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): differential expression of microRNAs during EndMT. Cell Signal. 2012;24:1031–1036.
    • (2012) Cell Signal , vol.24 , pp. 1031-1036
    • Ghosh, A.K.1    Nagpal, V.2    Covington, J.W.3    Michaels, M.A.4    Vaughan, D.E.5
  • 27
    • 33845524077 scopus 로고    scopus 로고
    • Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300
    • Kaur H, Chen S, Xin X, Chiu J, Khan ZA, Chakrabarti S. Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300. Diabetes. 2006; 55:3104–3111.
    • (2006) Diabetes , vol.55 , pp. 3104-3111
    • Kaur, H.1    Chen, S.2    Xin, X.3    Chiu, J.4    Khan, Z.A.5    Chakrabarti, S.6
  • 28
    • 79953225170 scopus 로고    scopus 로고
    • MicroRNA-200b regulates vascular endothelial growth factor-mediated alterations in diabetic retinopathy
    • McArthur K, Feng B, Wu Y, Chen S, Chakrabarti S. MicroRNA-200b regulates vascular endothelial growth factor-mediated alterations in diabetic retinopathy. Diabetes. 2011;60:1314–1323.
    • (2011) Diabetes , vol.60 , pp. 1314-1323
    • McArthur, K.1    Feng, B.2    Wu, Y.3    Chen, S.4    Chakrabarti, S.5
  • 31
    • 84875487362 scopus 로고    scopus 로고
    • MiR-320 regulates glucose-induced gene expression in diabetes
    • 549875
    • Feng B, Chakrabarti S. miR-320 regulates glucose-induced gene expression in diabetes. ISRN Endocrinol. 2012;2012:549875.
    • ISRN Endocrinol. 2012
    • Feng, B.1    Chakrabarti, S.2
  • 32
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5:522–531.
    • (2004) Nat Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 33
    • 78649448548 scopus 로고    scopus 로고
    • Post-transcriptional gene-expression regulation by micro RNA (miRNA) network in renal disease
    • Kaucsár T, Rácz Z, Hamar P. Post-transcriptional gene-expression regulation by micro RNA (miRNA) network in renal disease. Adv Drug Deliv Rev. 2010;62:1390–1401.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 1390-1401
    • Kaucsár, T.1    Rácz, Z.2    Hamar, P.3
  • 34
    • 77956230322 scopus 로고    scopus 로고
    • The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer?
    • Brabletz S, Brabletz T. The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer? EMBO Rep. 2010;11:670–677.
    • (2010) EMBO Rep , vol.11 , pp. 670-677
    • Brabletz, S.1    Brabletz, T.2
  • 35
    • 84878655790 scopus 로고    scopus 로고
    • MiRNA-200b represses transforming growth factor-b1-induced EMT and fibronectin expression in kidney proximal tubular cells
    • Tang O, Chen XM, Shen S, Hahn M, Pollock CA. MiRNA-200b represses transforming growth factor-b1-induced EMT and fibronectin expression in kidney proximal tubular cells. Am J Physiol Renal Physiol. 2013;304:F1266–273.
    • (2013) Am J Physiol Renal Physiol , vol.304 , pp. F1266-F1273
    • Tang, O.1    Chen, X.M.2    Shen, S.3    Hahn, M.4    Pollock, C.A.5
  • 36
    • 84857631069 scopus 로고    scopus 로고
    • MiR-200b is involved in TGF-b signaling to regulate mammalian palate development
    • Shin JO, Lee JM, Cho KW, et al. MiR-200b is involved in TGF-b signaling to regulate mammalian palate development. Histo-chem Cell Biol. 2012;137:67–78.
    • (2012) Histo-Chem Cell Biol , vol.137 , pp. 67-78
    • Shin, J.O.1    Lee, J.M.2    Cho, K.W.3
  • 38
    • 0030965208 scopus 로고    scopus 로고
    • Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice
    • Schlaeger TM, Bartunkova S, Lawitts JA. Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice. Proc Natl Acad Sci U S A. 1997;94: 3058–3063.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3058-3063
    • Schlaeger, T.M.1    Bartunkova, S.2    Lawitts, J.A.3
  • 39
    • 8644263977 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice
    • Peng X, Ueda H, Zhou H. Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice. Cardiovasc Res. 2004;64:421–430.
    • (2004) Cardiovasc Res , vol.64 , pp. 421-430
    • Peng, X.1    Ueda, H.2    Zhou, H.3
  • 40
    • 84860898777 scopus 로고    scopus 로고
    • Genotoxic stress and activation of novel DNA repair enzymes in human endothelial cells and in the retinas and kidneys of streptozotocin diabetic rats
    • Wang C, George B, Chen S, Feng B, Li X, Chakrabarti S. Genotoxic stress and activation of novel DNA repair enzymes in human endothelial cells and in the retinas and kidneys of streptozotocin diabetic rats. Diabetes Metab Res Rev. 2012;28: 329–337.
    • (2012) Diabetes Metab Res Rev , vol.28 , pp. 329-337
    • Wang, C.1    George, B.2    Chen, S.3    Feng, B.4    Li, X.5    Chakrabarti, S.6
  • 41
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor Snail controls epithelial-mesenchymal transitions by repressing Ecadherin expression
    • Cano A, Perez-Moreno MA, Rodrigo I. The transcription factor Snail controls epithelial-mesenchymal transitions by repressing Ecadherin expression. Nat Cell Biol. 2000;2:76–83.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 43
    • 74149085153 scopus 로고    scopus 로고
    • Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis
    • Liu RM, Gaston Pravia KA. Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis. Free Radic Biol Med. 2010; 48:1–15.
    • (2010) Free Radic Biol Med , vol.48 , pp. 1-15
    • Liu, R.M.1    Gaston Pravia, K.A.2
  • 44
    • 84875481512 scopus 로고    scopus 로고
    • Oxidative-stress-induced epigenetic changes in chronic diabetic complications
    • Feng B, Ruiz MA, Chakrabarti S. Oxidative-stress-induced epigenetic changes in chronic diabetic complications. Can J Physiol Pharmacol. 2013;91:213–220.
    • (2013) Can J Physiol Pharmacol , vol.91 , pp. 213-220
    • Feng, B.1    Ruiz, M.A.2    Chakrabarti, S.3
  • 46
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005;54:1615–1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1


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