Genotoxic stress and activation of novel DNA repair enzymes in human endothelial cells and in the retinas and kidneys of streptozotocin diabetic rats

Diabetes/Metabolism Research and Reviews

Volumn 28, Issue 4, 2012, Pages 329-337

  Wang, Chunyan ^a,b   George, Biju ^a   Chen, Shali ^a   Feng, Biao ^a   Li, Xiaokun ^c   Chakrabarti, Subrata ^a  

^a WESTERN UNIVERSITY   (Canada)

^b JILIN UNIVERSITY   (China)

^c Basic Medical College   (China)

Author keywords

DNA damage; Endothelial cells; ERCC; Fibronectin; Kidney; Retina

Indexed keywords

3 AMINOBENZAMIDE; BETA ACTIN; CURCUMIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FIBRONECTIN; GLUCOSE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; PROTEIN ERCC4; PROTEIN P300; SCLEROPROTEIN; SMALL INTERFERING RNA; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; DNA REPAIR; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENETIC TRANSFECTION; GENOTOXIC STRESS; HUMAN; KIDNEY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RETINA; STREPTOZOCIN DIABETES; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BENZAMIDES; BLOTTING, WESTERN; CURCUMIN; DIABETES MELLITUS, EXPERIMENTAL; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FIBRONECTINS; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; POLY(ADP-RIBOSE) POLYMERASES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, SMALL INTERFERING;

EID: 84860898777     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2279     Document Type: Article

References (40)

1. Giugliano D, Ceriello A, Paolisso G. Diabetes mellitus, hypertension, and cardiovascular disease: which role for oxidative stress? Metabolism 1995; 44: 363-368.
2. Mohamed AK, Bierhaus A, Schiekofer S, Tritschler H, Ziegler R, Nawroth PP. The role of oxidative stress and NF-kappaB activation in late diabetic complications. Biofactors 1999; 10: 157-167.
3. Helenius M, Hänninen M, Lehtinen SK, Salminen A. Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-kB transcription factor in mouse cardiac muscle. J Mol Cell Cardiol 1996; 28: 487-498.
4. Chiu J, Farhangkhoee H, Xu BY, Chen S, George B, Chakrabarti S. PARP mediates structural alterations in diabetic cardiomyopathy. J Mol Cell Cardiol 2008; 45: 385-393.
5. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001; 414: 813-820.
6. Chakrabarti S, Khan ZA, Cukiernik M, Fukuda G, Chen S, Mukherjee S. Alteration of endothelins: a common pathogenetic mechanism in chronic diabetic complications. Int J Exp Diabetes Res 2002; 3: 217-231.
7. Thompson LH, Hinz JM, AliceYamada N, Jones N. How Fanconi anemia proteins promote the four R's: replication, recombination, repair, and recovery. Environ Mol Mutagen 2005; 45: 128-142.
8. Kirschner K, Melton DW. Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs. Anticancer Res 2010; 30: 3223-3232.
9. Wood RD. Mammalian nucleotide excision repair proteins and interstrand crosslink repair. Environ Mol Mutagen 2010; 51: 520-526.
10. McDaniel LD, Schultz RA. XPF/ERCC4 and ERCC1: their products and biological roles. Adv Exp Med Biol 2008; 637: 65-82.
11. Prasher JM, Lalai AS, Heijmans-Antonissen C, et al. Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice. EMBO J 2005; 24: 861-871.
12. Jaspers NG, Raams A, Silengo MC, Wijgers N, Hoeijmakers JH, Vermeulen W. First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure. Am J Hum Genet 2007; 80: 457-466.
13. Shahzad MM, Lopez-Berestein G, Sood AK. Novel strategies for reversing platinum resistance. Drug Resist Updat 2009; 12: 148-152.
14. Manna P, Das J, Ghosh J, Sil PC. Contribution of type 1 diabetes to rat liver dysfunction and cellular damage via activation of NOS, PARP, IkappaBalpha/NF-kappaB, MAPKs, and mitochondria-dependent pathways: prophylactic role of arjunolic acid. Free Radic Biol Med 2010; 48: 1465-1484.
15. Hassa PO, Buerki C, Lombardi C, Imhof R, Hottinger MO. Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1. J Biol Chem 2003; 278: 45145-45153.
16. Xu BY, Chiu J, Feng B, Chen S, Chakrabarti S. PARP activation and the alteration of vasoactive factors and extracellular matrix protein in retina and kidney in diabetes. Diabetes Metab Res Rev 2008; 24: 404-412.
17. Kaur H, Chen S, Xin X, Chiu J, Khan ZA, Chakrabarti S. Diabetes-induced extracellular matrix protein expression is mediated by transcription co-activator p300. Diabetes 2006; 55: 3104-3111.
18. Chen S, Khan ZA, Cukiernik M, Chakrabarti S. Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications. Am J Physiol Endocrinol Metab 2003; 284: E1089-E1097.
19. Farhangkhoee H, Khan ZA, Chen S, Chakrabarti S. Differential effects of curcumin on vasoactive factors in the diabetic rat heart. Nutr Metab 2006; 3: 27-34.
20. Nan B, Lin P, Lumsden AB, Yao Q, Chen C. Effects of TNF-alpha and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. Thromb Res 2005; 115: 417-426.
21. Marcu MG, Jung YJ, Lee S. Curcumin is an inhibitor of p300 histone acetyltransferase. Med Chem 2006; 2: 169-174.
22. Weberpals J, Garbuio K, O'Brien A, et al. The DNA repair proteins BRCA1 and ERCC1 as predictive markers in sporadic ovarian cancer. Int J Cancer 2009; 124: 806-815.
23. Khan ZA, Chan BM, Uniyal S, et al. EDB fibronectin and angiogenesis-a novel mechanistic pathway. Angiogenesis 2005; 8: 183-196.
24. Obrosova IG, Li F, Abatan OI, et al. Role of poly(ADP-ribose) polymerase in diabetic neuropathy. Diabetes 2004; 53: 711-720.
25. Chen S, Mukherjee S, Chakrabarti S. Glucose-induced endothelin-dependent increased extracellular matrix protein synthesis is mediated via NF-κB and AP-1. Am J Physiol Cell Physiol 2003; 284: C263-C272.
26. Khan ZA, Cukiernik M, Gonder JR, Chakrabarti S. Oncofetal fibronectin in diabetic retinopathy. Invest Ophthalmol Vis Sci 2004; 45: 287-295.
27. Chen S, Feng B, George B, Chakrabarti R, Chen M, Chakrabarti S. Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells. Am J Physiol Endocrinol Metab 2010; 298: E127-E137.
28. Chen S, Apostolova MD, Cherian MG, Chakrabarti S. Interaction of endothelin-1 with vasoactive factors in mediating glucose-induced increased permeability in endothelial cells. Lab Invest 2000; 80: 1311-1321.
29. Szabó C. PARP as a drug target for the therapy of diabetic cardiovascular dysfunction. Drug News Perspect 2002; 15: 197.
30. Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. A DNA repair pathways as targets for cancer therapy. Nat Rev Cancer 2008; 8: 193-204.
31. de Boer J, Hoeijmakers JH. Cancer from the outside, aging from the inside: mouse models to study the consequences of defective nucleotide excision repair. Biochimie 1999; 81: 127-137.
32. de Laat WL, Jaspers NG, Hoeijmakers JH. Molecular mechanism of nucleotide excision repair. Genes Dev 1999; 13: 768-785.
33. Minamino T, Komuro I. Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes. Nat Clin Pract Cardiovasc Med 2008; 5: 637-648.
34. Minamino T, Komuro I. Vascular cell senescence. Circ Res 2007; 100: 15.
35. Minamino T, Miyauchi H, Yoshida T, Tateno K, Kunieda T, Komuro I. Vascular cell senescence and vascular aging. J Mol Cell Cardiol 2004; 36: 175-183.
36. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000; 408: 239-247.
37. Golubnitschaja O, Moenkemann H, Trog DB, Blom HJ, De Vriese AS. Activation of genes inducing cell-cycle arrest and of increased DNA repair in the hearts of rats with early streptozotocin-induced diabetes mellitus. Med Sci Monit 2006; 12: BR68-74.
38. Wood RD. DNA damage recognition during nucleotide excision repair in mammalian cells. Biochimie 1999; 81: 1-2.
39. Hamanaka RB, Chandel NS. Cell biology. Warburg effect and redox balance. Science 2011; 2(334): 1219-1220.
40. Wynn ML, Merajver SD, Schnell S. Unraveling the complex regulatory relationships between metabolism and signal transduction in cancer. Adv Exp Med Biol 2012; 736: 179-189.