Chemokine receptor CXCR4 is a novel marker for the progression of cutaneous malignant melanomas

Acta Histochemica et Cytochemica

Volumn 45, Issue 5, 2012, Pages 293-299

  Toyozawa, Seiko ^a   Kaminaka, Chikako ^a   Furukawa, Fukumi ^a   Nakamura, Yasushi ^a   Matsunaka, Hiroshi ^a   Yamamoto, Yuki ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Chemokine; CXCL12; CXCR4; Immunohistochemistry; Malignant melanoma

Indexed keywords

EID: 84868374270     PISSN: 00445991     EISSN: 13475800     Source Type: Journal    
DOI: 10.1267/ahc.12004     Document Type: Article

References (22)

1. Bartolomé, R. A., Gálvez, B. G., Longo, N., Baleux, F., Van Muijen, G. N., Sánchez-Mateos, P., Arroyo, A. G. and Teixidó, J. (2004) Stromal dell-derived factor-1α promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities. Cancer Res. 64; 2534-2543.
2. Bleul, C. C., Farzan, M., Choe, H., Parolin, C., Clark-Lewis, I., Sodroski, J. and Springer, T. A. (1996) The lymphocyte chemo-attractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382; 829-833.
3. Ding, Y., Shimada, Y., Maeda, M., Kawabe, A., Kaganoi, J., Komoto, I., Hashimoto, Y., Miyake, M., Hashida, H. and Imamura, M. (2003) Association of CC chemokine 7 with lymph node metastasis of esophageal squamous cell carcinoma. Clin. Cancer Res. 9; 3406-3412.
4. Kaminaka, C., Toyozawa, S., Yonei, N., Kunimoto, K., Furukawa, F. and Yamamoto, Y. (2011) Phenol peels for the treatment of actinic keratosis and Bowen's disease: correlation with chemokine receptors expression. Skin Cancer 26; 327-332 (Abstract in English).
5. Kawada, K., Sonoshita, M., Sakashita, H., Takabayashi, A., Yamaoka, Y., Manabe, T., Inaba, K., Minato, N., Oshima, M. and Taketo, M. M. (2004) Pivotal rale of CXCR3 in melanoma cell metastasis to lymph nodes. Cancer Res. 64; 4010-4017.
6. Kim, J., Takeuchi, H., Lam, S. T., Turner, R. R., Wang, H. J., Kuo, C., Foshag, L., Bilchik, A. J. and Hoon, D. S. (2005) Chemokine receptor CXCR4 expression in colorectal cancer patients increase the risk for reccurence and for poor survival. J. Clin. Oncol. 23; 2744-2753.
7. Laverdiere, C., Hoang, B. H., Yang, R., Sowers, R., Qin, J., Meyers, P. A., Huvos, A. G., Healey, J. H. and Gorlick, R. (2005) Messenger RNA expression levels of CXCR4 correlate with metastatic behavior and outcome in patients with osteosarcoma. Clin. Cancer Res. 11; 2561-2567.
8. Liu, Y., Ji, R., Li, J., Gu, Q., Zhao, X., Sun, T., Wang, J., Li, J., Du, Q. and Sun, B. (2010) Correlation effect of EGFR and CXCR4 and CCR7 chemokine receptors in predicting breast cancer metastasis and prognosis. J. Exp. Clin. Cancer Res. 29; 16-25.
9. Longo-Imedio, M. I., Longo, N., Treviño, I., Lázaro, P. and Sánchez-Mateos, P. (2005) Clinical significance of CXCR3 and CXCR4 expression in primary melanoma. Int. J. Cancer 117; 861-865.
10. Mashino, K., Sadanaga, N., Yamaguchi, H., Tanaka, F., Ohta, M., Shibuta, K., Inoue, H. and Mori, M. (2002) Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma. Cancer Res. 62; 2937-2941.
11. Müller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M. E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S. N., Barrera, J. L., Mohar, A., Verástegui, E. and Zlotnik, A. (2001) Involvement of chemokine receptor in breast cancer metastasis. Nature 410; 50-56.
12. Murakami, T., Maki, W., Cardones, A. R., Fang, H., Tun Kyi, A., Nestle, F. O. and Hwang, S. T. (2002) Expression of CXC chemokine receptor-4 enhance the pulmonary metastasis potential of murine B16 melanoma cells. Cancer Res. 62; 7328-7334.
13. Murakami, T., Cardones, A. R. and Hwang, S. T. (2004) Chemo-kine receptors and melanoma metastasis. J. Dermatol. Sci. 36; 71-78.
14. Robledo, M. M., Bartolome, R. A., Longo, N., Rodríguez-Frade, J. M., Mellado, M., Longo, I., van Muijen, G. N., Sánchez-Mateos, P. and Teixidó, J. (2001) Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells. J. Biol. Chem. 276; 45098-45105.
15. Saeki, H., Moor, A. M., Brown, M. J. and Hwang, S. T. (1999) Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 162; 2472-2475.
16. Saur, D., Seidler, B., Schneider, G., Algül, H., Beck, R., Senekowitsch-Schmidtke, R., Schwaiger, M. and Schmid, R. M. (2005) CXCR4 expression increases liver lung metastasis in a mouse model of pancreatic cancer. Gastroenterology 129; 1237-1250.
17. Scala, S., Ottaiano, A., Ascierto, P. A., Cavalli, M., Simeone, E., Giuliano, P., Napolitano, M., Franco, R., Botti, G. and Castello, G. (2005) Expression of CXCR4 predicts poor prognosis in patients with malignant melanoma. Clin. Cancer Res. 11; 1835-1841.
18. Scala, S., Giuliano, P., Ascierto, P. A., Ieranò, C., Franco, R., Napolitano, M., Ottaiano, A., Lombardi, M. L., Luongo, M., Simeone, E., Castiglia, D., Mauro, F., De Michele, I., Calemma, R., Botti, G., Caracò, C., Nicoletti, G., Satriano, R. A. and Castello, G. (2006) Human melanoma metastases express functional CXCR4. Clin. Cancer Res. 12; 2427-2433.
19. Takeuchi, H., Fujimoto, A., Tanaka, M., Yamano, T., Hsueh, E. and Hoon, D. S. (2004) CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells. Clin. Cancer Res. 10; 2351-2358.
20. Toyozawa, S., Yamamoto, Y., Ishida, Y., Kondo, T., Nakamura, Y. and Furukawa, F. (2010) Immunohistochemical analysis of CXCR4 expression in fibrohistiocytic tumors. Acta Histochem. Cytochem. 43; 45-50.
21. Wang, J., Xi, L., Hunt, J. L., Gooding, W., Whiteside, T. L., Chen, Z., Godfrey, T. E. and Ferris, R. L. (2004) Expression pattern of chemokine receptor (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies novel metastatic potential. Cancer Res. 64; 1861-1866.
22. Zlotnik, A. (2006) Chemokines and cancer. Int. J. Cancer 119; 2026-2029.