Benzo[a]pyrene-induced cell cycle progression occurs via ERK-induced Chk1 pathway activation in human lung cancer cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 773, Issue , 2015, Pages 1-8

  Wang, Bing Yen ^a,b   Wu, Sung Yu ^a   Tang, Sheau Chung ^a,c,d   Lai, Chien Hung ^c,d   Ou, Chu Chyn ^a   Wu, Ming Fang ^a,e   Hsiao, Yi Min ^f   Ko, Jiunn Liang ^a,e  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

^d Hualien Hospital   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Benzo a pyrene; Chk1; ERK; P p53; S phase accumulation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BENZO[A]PYRENE; CHECKPOINT KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PHOSPHOPROTEIN; PROTEIN BAX; PROTEIN P53; SERINE; PROTEIN KINASE;

ARTICLE; BIOACCUMULATION; CELL ACTIVATION; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; LUNG CANCER CELL LINE; NON SMALL CELL LUNG CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL CYCLE; CELL CYCLE CHECKPOINT; DRUG EFFECTS; LUNG NEOPLASMS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

NICOTIANA TABACUM;

BENZO(A)PYRENE; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LUNG NEOPLASMS; PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 84922272017     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2015.01.009     Document Type: Article

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