CD4+CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses

Journal of Hepatology

Volumn 62, Issue 2, 2015, Pages 303-310

  Spaan, Michelle ^a   Kreefft, Kim ^a   De Graav, Gretchen N ^a   Brouwer, Willem P ^a   De Knegt, Robert J ^a   Ten Kate, Fibo J W ^a   Baan, Carla C ^a   Vanwolleghem, Thomas ^a   Janssen, Harry L A ^a,b   Boonstra, Andre ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Chronic hepatitis C; IL 21; Immunology; Intrahepatic; T follicular helper cells

Indexed keywords

CD20 ANTIGEN; CD27 ANTIGEN; CD3 ANTIGEN; CHEMOKINE RECEPTOR CXCR5; GAMMA INTERFERON; ICOS PROTEIN; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 21; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN; PROTEIN BCL 6; UNCLASSIFIED DRUG; CXCR5 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

ADULT; ARTICLE; B CELL CULTURE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CD4+ CXCR5+ T LYMPHOCYTE; CELL MATURATION; CELL STIMULATION; CELL SURFACE; CLINICAL ARTICLE; COCULTURE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; HEPATITIS C; HUMAN; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER FIBROSIS; LYMPHOCYTE FUNCTION; MALE; MEMORY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; VIRAL CLEARANCE; BIOSYNTHESIS; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; HELPER CELL; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION;

ADULT; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HEPATITIS C, CHRONIC; HUMANS; IMMUNITY, CELLULAR; INTERLEUKINS; MALE; MIDDLE AGED; RECEPTORS, CXCR5; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84922267705     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.09.024     Document Type: Article

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