Lower wake resting sympathetic and cardiovascular activities in narcolepsy with cataplexy

Neurology

Volumn 83, Issue 12, 2014, Pages 1080-1086

  Donadio, Vincenzo ^a   Liguori, Rocco ^a,b   Vandi, Stefano ^a,b   Pizza, Fabio ^a,b   Dauvilliers, Yves ^c   Leta, Valentina ^a   Giannoccaro, Maria Pia ^a,b   Baruzzi, Agostino ^a   Plazzi, Giuseppe ^a,b  

^a IRCCS ISTITUTO DELLE SCIENZE NEUROLOGICHE DI BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c GUI DE CHAULIAC HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

OREXIN A; NEUROPEPTIDE; OREXINS; SIGNAL PEPTIDE;

ADULT; ARTICLE; ASSESSMENT OF HUMANS; BLOOD PRESSURE; BODY MASS; CATAPLEXY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ELECTROSTIMULATION; FEMALE; HEART RATE; HUMAN; MALE; MIDDLE AGED; MULTIPLE SLEEP LATENCY TEST; MUSCLE SYMPATHETIC NERVE ACTIVITY; NARCOLEPSY; NARCOLEPSY WITH CATAPLEXY; NEUROGRAPHY; PERONEUS NERVE; POLYSOMNOGRAPHY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SPHYGMOMANOMETER; SYMPATHETIC TONE; WAKEFULNESS; YOUNG ADULT; ADRENERGIC SYSTEM; CASE CONTROL STUDY; CEREBROSPINAL FLUID; DEFICIENCY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; BLOOD PRESSURE; CASE-CONTROL STUDIES; CATAPLEXY; FEMALE; HEART RATE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; NARCOLEPSY; NEUROPEPTIDES; PERONEAL NERVE; SYMPATHETIC NERVOUS SYSTEM; WAKEFULNESS; YOUNG ADULT;

EID: 84922264346     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000000793     Document Type: Article

References (40)

1. Aldrich MS. The neurobiology of narcolepsy-cataplexy. Prog Neurobiol 1993;41:533-541.
2. Samson WK, Gosnell B, Chang JK, Resch ZT, Murphy TC. Cardiovascular regulatory actions of the hypocretins in brain. Brain Res 1999;831:248-253.
3. Shirasaka T, Nakazato M, Matsukura S, Takasaki M, Kannan H. Sympathetic and cardiovascular actions of orexins in conscious rats. Am J Physiol Regul Integr Comp Physiol 1999;277:R1780-R1785.
4. Antunes VR, Brailoiu GC, Kwok EH, Scruggs P, Dun NJ. Orexins/hypocretins excite rat sympathetic preganglionic neurons in vivo and in vitro. Am J Physiol Regul Integr Comp Physiol 2001;281:R1801-R1807.
5. Dauvilliers Y, Pennestri MH, Whittom S, Lanfranchi PA, Montplaisir JY. Autonomic response to periodic leg movements during sleep in narcolepsy-cataplexy. Sleep 2011; 34:219-223.
6. Plazzi G, Moghadam KK, Maggi LS, et al. Autonomic disturbances in narcolepsy. Sleep Med Rev 2011;15:187-196.
7. Fronczek R, Overeem S, Reijntjes R, Lammers GJ, van Dijk JG, Pijl H. Increased heart rate variability but normal resting metabolic rate in hypocretin/orexin-deficient human narcolepsy. J Clin Sleep Med 2008;4:248-254.
8. Grimaldi D, Calandra-Buonaura G, Provini F, et al. Abnormal sleep-cardiovascular system interaction in narcolepsy with cataplexy: effects of hypocretin deficiency in humans. Sleep 2012;35:519-528.
9. Elam M. Cardiac neural discharge preceding sudden death: efferent, afferent or both? Clin Auton Res 2003;13:314-315.
10. Narkiewicz K, Wolf J, Lopez-Jimenez F, Somers VK. Obstructive sleep apnea and hypertension. Curr Cardiol Rep 2005;7:435-440.
11. Poli F, Plazzi G, Di Dalmazi G, et al. Body mass index-independent metabolic alterations in narcolepsy with cataplexy. Sleep 2009;32:1491-1497.
12. Jennum P, Ibsen R, Knudsen S, Kjellberg J. Comorbidity and mortality of narcolepsy: a controlled retro-and prospective national study. Sleep 2013;36:835-840.
13. American Academy of Sleep Medicine. International Classification of Sleep Disorders: Diagnostic & Coding Manual, 2nd ed. Westchester, IL: American Academy of Sleep Medicine; 2005:81-86.
14. Donadio V, Montagna P, Pennisi M, et al. Agrypnia excitata: a microneurographic study of muscle sympathetic nerve activity. Clin Neurophysiol 2009;120:1139-1142.
15. Liguori R, Giannoccaro MP, Di Stasi V, et al. Microneurographic evaluation of sympathetic activity in small fiber neuropathy. Clin Neurophysiol 2011;122:1854-1859.
16. Donadio V, Liguori R, Elam M, et al. Muscle sympathetic response to arousal predicts neurovascular reactivity during mental stress. J Physiol 2012;590:2885-2896.
17. Dun NJ, Le Dun S, Chen CT, Hwang LL, Kwok EH, Chang JK. Orexins: a role in medullary sympathetic outflow. Regul Pept 2000;96:65-70.
18. Siegel JM. Hypocretin (orexin): role in normal behavior and neuropathology. Annu Rev Psychol 2004;55:125-148.
19. Kayaba Y, Nakamura A, Kasuya Y, et al. Attenuated defense response and low basal blood pressure in orexin knockout mice. Am J Physiol Regul Integr Comp Physiol 2003;285:R581-R593.
20. Zhang W, Fukuda Y, Kuwaki T. Respiratory and cardiovascular actions of orexin-A in mice. Neurosci Lett 2005; 385:131-136.
21. Zhang W, Sakurai T, Fukuda Y, Kuwaki T. Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice. Am J Physiol Regul Integr Comp Physiol 2006;290:R1654-R1663.
22. Schwimmer H, Stauss HM, Abboud F, Nishino S, Mignot E, Zeitzer JM. Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins. J Appl Physiol 2010;109:1053-1063.
23. Grimaldi D, Pierangeli G, Barletta G, et al. Spectral analysis of heart rate variability reveals an enhanced sympathetic activity in narcolepsy with cataplexy. Clin Neurophysiol 2010;121: 1142-1147.
24. Van den Pol AN. Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J Neurosci 1999; 19:3171-3182.
25. Ferini-Strambi L, Spera A, Oldani A, et al. Autonomic function in narcolepsy: power spectrum analysis of heart rate variability. J Neurol 1997;244:252-255.
26. Shirasaka T, Kunitake T, Takasaki M, Kannan H. Neuronal effects of orexins: relevant to sympathetic and cardiovascular functions. Regul Pept 2002;104:91-95.
27. Dauvilliers Y, Jaussent I, Krams B, et al. Non-dipping blood pressure profile in narcolepsy with cataplexy. PLoS One 2012;7:e38977.
28. Wallin BG, Esler M, Dorward P, et al. Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans. J Physiol 1992;453:45-58.
29. Matsumura K, Tsuchihashi T, Abe I. Central orexin-A augments sympathoadrenal outflow in conscious rabbits. Hypertension 2001;37:1382-1387.
30. Chen CT, Hwang LL, Chang JK, Dun NJ. Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rats. Am J Physiol Regul Integr Comp Physiol 2000;278:R692-R697.
31. Hart EC, Joyner MJ, Wallin BG, Charkoudian N. Sex, ageing and resting blood pressure: gaining insights from the integrated balance of neural and haemodynamic factors. J Physiol 2012;590:2069-2079.
32. Sachs C, Kaijser L. Autonomic regulation of cardiopulmonary functions in sleep apnea syndrome and narcolepsy. Sleep 1982;5:227-238.
33. Mitler MM, Hajdukovic R, Erman MK. Treatment of narcolepsy with methamphetamine. Sleep 1993;16:306-317.
34. Donadio V, Plazzi G, Vandi S, et al. Sympathetic and cardiovascular activity during cataplexy in narcolepsy. J Sleep Res 2008;17:458-463.
35. Scherrer U, Randin D, Tappy L, Vollenweider P, Jéquier E, Nicod P. Body fat and sympathetic nerve activity in healthy subjects. Circulation 1994;89:2634-2640.
36. Jones PP, Davy KP, Alexander S, Seals DR. Age-related increase in muscle sympathetic nerve activity is associated with abdominal adiposity. Am J Physiol 1997;272:E976-E980.
37. Sayk F, Heutling D, Dodt C, et al. Sympathetic function in human carriers of melanocortin-4 receptor gene mutations. J Clin Endocrinol Metab 2010;95:1998-2002.
38. Lambert E, Straznicky N, Eikelis N, et al. Gender differences in sympathetic nervous activity: influence of body mass and blood pressure. J Hypertens 2007;25:1411-1419.
39. Silvani A, Bastianini S, Berteotti C, et al. Sleep and cardiovascular phenotype in middle-aged hypocretin-deficient narcoleptic mice. J Sleep Res 2014;23:98-106.
40. Ohayon MM, Black J, Lai C, Eller M, Guinta D, Bhattacharyya A. Increased mortality in narcolepsy. Sleep 2014;37:439-444.