Spectral analysis of heart rate variability reveals an enhanced sympathetic activity in narcolepsy with cataplexy

Clinical Neurophysiology

Volumn 121, Issue 7, 2010, Pages 1142-1147

  Grimaldi, D ^a   Pierangeli, G ^a   Barletta, G ^a   Terlizzi, R ^a   Plazzi, G ^a   Cevoli, S ^a   Franceschini, C ^a   Montagna, P ^a   Cortelli, P ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Heart rate variability (HRV); Hypocretin; Narcolepsy with cataplexy; Sympathetic activity

Indexed keywords

OREXIN;

ADULT; ARTICLE; BREATHING; CARDIOVASCULAR AUTOREGULATION; CARDIOVASCULAR REFLEX; CATAPLEXY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOURIER TRANSFORMATION; HAND GRIP; HEAD TILTING; HEART RATE VARIABILITY; HUMAN; LABORATORY TEST; MALE; MUSCLE ISOMETRIC CONTRACTION; NARCOLEPSY; ORTHOSTATIC STRESS; PRIORITY JOURNAL; REST; SPECTROSCOPY; SUPINE POSITION; SYMPATHETIC TONE; VALSALVA MANEUVER;

ADULT; CATAPLEXY; ELECTROCARDIOGRAPHY; FEMALE; FOURIER ANALYSIS; HEART RATE; HUMANS; MALE; MIDDLE AGED; NARCOLEPSY; SYMPATHETIC NERVOUS SYSTEM; TILT-TABLE TEST; VALSALVA MANEUVER;

EID: 77952741710     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2010.01.028     Document Type: Article

References (22)

1. American Academy of Sleep Medicine. ICSD-2-international classification of sleep disorders. Diagnostic and coding manual, 2nd ed. American Academy of Sleep Medicine; 2005.
2. Burr R.L. Interpretation of normalized spectral heart rate variability indices in sleep research: a critical review. Sleep 30 (2007) 913-919
3. de Oliveira C.V., Rosas-Arellano M.P., Solano-Flores L.P., and Ciriello J. Cardiovascular effects of hypocretin-1 in nucleus of the solitary tract. Am J Physiol Heart Circ Physiol 284 (2003) H1369-H1377
4. Ferguson A.V., and Samson W.K. The orexin/hypocretin system: a critical regulator of neuroendocrine and autonomic function. Front Neuroendocrinol 24 (2003) 141-150
5. Ferini-Strambi L., Spera A., Oldani A., Zucconi M., Bianchi A., Cerutti S., et al. Autonomic function in narcolepsy: power spectrum analysis of heart rate variability. J Neurol 244 (1997) 252-255
6. Fisher J.P., Young C.N., and Fadel P.J. Central sympathetic overactivity: maladies and mechanisms. Auton Neurosci 148 (2009) 5-15
7. Fronczek R., Overeem S., Reijntjes R., Lammers G.J., van Dijk J.G., and Pijl H. Increased heart rate variability but normal resting metabolic rate in hypocretin/orexin-deficient human narcolepsy. J Clin Sleep Med 4 (2008) 248-254
8. Goldstein D.S., Horwitz D., and Keiser H.R. Comparison of techniques for measuring baroreflex sensitivity in man. Circulation 66 (1982) 432-439
9. Hublin C., Matikainen E., and Partinen M. Autonomic nervous system function in narcolepsy. J Sleep Res 3 (1994) 131-137
10. Karacan I. Erectile dysfunction in narcoleptic patients. Sleep 9 (1986) 227-231
11. Malliani A., Pagani M., Lombardi F., and Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation 84 (1991) 482-492
12. Mathias CJ, Bannister R. Investigation of autonomic disorders. In: Mathias CJ, Bannister R, editors. Autonomic failure: a text book of clinical disorders of the autonomic nervous system, 4th ed. Oxford: Oxford University Press; 1999. p. 169-95.
13. Pagani M., Lombardi F., Guzzetti S., Rimoldi O., Furlan R., Pizzinelli P., et al. Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog. Circ Res 59 (1986) 178-193
14. Sachs C., and Kaijser L. Autonomic control of cardiovascular reflexes in narcolepsy. J Neurol Neurosurg Psychiatry 43 (1980) 535-539
15. Sachs C., and Kaijser L. Autonomic regulation of cardiopulmonary functions in sleep apnea syndrome and narcolepsy. Sleep 5 (1982) 227-238
16. Samson W.K., Gosnell B., Chang J.K., Resch Z.T., and Murphy T.C. Cardiovascular regulatory actions of the hypocretins in brain. Brain Res 831 (1999) 248-253
17. Shirasaka T., Nakazato M., Matsukura S., Takasaki M., and Kannan H. Sympathetic and cardiovascular actions of orexins in conscious rats. Am J Physiol 277 (1999) R1780-R1785
18. Smith P.M., Connolly B.C., and Ferguson A.V. Microinjection of orexin into the rat nucleus tractus solitarius causes increases in blood pressure. Brain Res 950 (2002) 261-267
19. Tarvainen M.P., Ranta-aho P.P., and Karjalainen P. An advanced detetrending method with application to HRV analysis. IEEE Trans Biomed Eng 49 (2002) 172-175
20. Task Force of the European Society of Cardiology and North American Society of Pacing and Electrophysiology. Heart rate variability-standards of measurement, physiological interpretation, and clinical use. Circulation 93 (1996) 1043-1065
21. Thayer J.F., Yamamoto S.S., and Brosschot J.F. The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. Int J Cardiol (2009) [e-pub]
22. Yoss R.E., Moyer N.J., and Ogle K.N. The pupillogram and narcolepsy. A method to measure decreased levels of wakefulness. Neurology 19 (1969) 921-928