The interaction between uPAR and vitronectin triggers ligand-independent adhesion signalling by integrins

EMBO Journal

Volumn 33, Issue 21, 2014, Pages 2458-2472

  Ferraris, Gian Maria Sarra ^a   Schulte, Carsten ^a,b   Buttiglione, Valentina ^a   De Lorenzi, Valentina ^a   Piontini, Andrea ^a   Galluzzi, Massimiliano ^b   Podestà, Alessandro ^b   Madsen, Chris D ^a,c   Sidenius, Nicolai ^a  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

integrin; membrane tension; signalling; uPAR; vitronectin

Indexed keywords

INTEGRIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; PAXILLIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TALIN; UROKINASE RECEPTOR; VINCULIN; VITRONECTIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CELL ACTIVATION; CELL ADHESION; CELL SPREADING; CELL SURFACE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; FOCAL ADHESION; GENE OVEREXPRESSION; HEK293 CELL LINE; HUMAN; HUMAN CELL; LIGAND BINDING; MECHANOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY;

CELL ADHESION; HEK293 CELLS; HUMANS; INTEGRINS; MUTATION; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; SIGNAL TRANSDUCTION; VITRONECTIN;

EID: 84922246831     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201387611     Document Type: Article

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