RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA

EMBO Reports

Volumn 16, Issue 2, 2015, Pages 221-231

  Manfrini, Nicola ^a   Trovesi, Camilla ^a   Wery, Maxime ^b   Martina, Marina ^a   Cesena, Daniele ^a   Descrimes, Marc ^b   Morillon, Antonin ^b   D'Adda Di Fagagna, Fabrizio ^c,d   Longhese, Maria Pia ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b INSTITUT CURIE   (France)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d CNR   (Italy)

Author keywords

DNA damage checkpoint; DNA double strand breaks; Rrp6; Trf4; Xrn1

Indexed keywords

ATR PROTEIN; CHROMATIN ASSEMBLY FACTOR 1; EXORIBONUCLEASE; FUNGAL DNA; FUNGAL RNA; GALACTOSE; GENOMIC DNA; HPA2 PROTEIN; HYDROXYUREA; MEC1 PROTEIN; MESYLIC ACID; PHLEOMYCIN; PROTEIN; RAD51 PROTEIN; RAD52 PROTEIN; RAFFINOSE; REPLICATION FACTOR A; RLF2 PROTEIN; RRP6 PROTEIN; SINGLE STRANDED DNA; SMC6 PROTEIN; TRANSCRIPTOME; TRF4 PROTEIN; UNCLASSIFIED DRUG; XRN1 PROTEIN; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; MEC1 PROTEIN, S CEREVISIAE; PAP2 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; RRP6 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE; XRN1 PROTEIN, S CEREVISIAE;

ALLELE; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ELECTROPHORETIC MOBILITY; EPISTASIS; FUNGAL STRAIN; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENOMIC INSTABILITY; GENOTYPE; HOMOLOGOUS RECOMBINATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT; RNA PROCESSING; SACCHAROMYCES CEREVISIAE; SOUTHERN BLOTTING; WILD TYPE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENETICS; METABOLISM; PHYSIOLOGY;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; EXORIBONUCLEASES; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN-SERINE-THREONINE KINASES; REPLICATION PROTEIN A; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84922241569     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201439458     Document Type: Article

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