Nanobubble-Affibody: Novel ultrasound contrast agents for targeted molecular ultrasound imaging of tumor

Biomaterials

Volumn 37, Issue , 2015, Pages 279-288

  Yang, Hengli ^a   Cai, Wenbin ^a   Xu, Lei ^a   Lv, Xiuhua ^a   Qiao, Youbei ^b   Li, Pan ^c   Wu, Hong ^b   Yang, Yilin ^a   Zhang, Li ^a   Duan, Yunyou ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Affibody; HER2; Molecular imaging; Nanobubbles; Ultrasound contrast agents

Indexed keywords

DIAGNOSIS; FILM GROWTH; FILM PREPARATION; FILM THICKNESS; PHOSPHOLIPIDS; TUMORS; ULTRASONIC IMAGING;

AFFIBODY; HER2; HUMAN EPIDERMAL GROWTH FACTOR; NANOBUBBLES; POLYDISPERSITY INDICES; QUANTITATIVE DIAGNOSIS; ULTRASOUND CONTRAST AGENT; ULTRASOUND ENHANCEMENTS;

MOLECULAR IMAGING;

ANTIBODY CONJUGATE; DIPALMITOYLPHOSPHATIDYLCHOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2 ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; NANOBUBBLE; PERFLUTREN; SONOVUE; UNCLASSIFIED DRUG; CONTRAST MEDIUM; HYBRID PROTEIN; LIPOSOME; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOTINYLATION; CANCER DIAGNOSIS; CELL VIABILITY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR IMAGING; MOLECULAR WEIGHT; MOUSE; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REAL TIME ULTRASOUND SCANNER; ULTRASOUND; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; CONFOCAL MICROSCOPY; DIAGNOSTIC IMAGING; DIAGNOSTIC USE; ECHOGRAPHY; FROZEN SECTION; NEOPLASM; NUDE MOUSE; PROCEDURES; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; CELL LINE, TUMOR; CONTRAST MEDIA; DIAGNOSTIC IMAGING; FEMALE; FROZEN SECTIONS; HUMANS; LIPOSOMES; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, CONFOCAL; NANOPARTICLES; NEOPLASMS; RECOMBINANT FUSION PROTEINS; ULTRASONICS;

EID: 84922238908     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.10.013     Document Type: Article

References (32)

1. Thakor A.S., Gambhir S.S. Nanooncology: the future of cancer diagnosis and therapy. CA Cancer J Clin 2013, 10.3322/caac.21199.
2. Yin T., Wang P., Zheng R., Zheng B., Cheng D., Zhang X., et al. Nanobubbles for enhanced ultrasound imaging of tumors. Int J Nanomed 2012, 7:895-904.
3. Ferrara K.W., Borden M.A., Zhang H. Lipid-shelled vehicles: engineering for ultrasound molecular imaging and drug delivery. Acc Chem Res 2009, 42:881-892.
4. Hobbs Susan K., Monsky Wayne L., Yuan Fan, Roberts W.Gregory, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Med Sci 1998, 95:4607-4612.
5. Oeffinger B.E., Wheatley M.A. Development and characterization of a nano-scale contrast agent. Ultrasonics 2004, 42:343-347.
6. Kim C., Qin R., Xu J.S., Wang L.V., Xu R. Multifunctional microbubbles and nanobubbles for photoacoustic and ultrasound imaging. JBiomed Opt 2010, 15:010510.
7. Rapoport N., Gao Z., Kennedy A. Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy. JNatl Cancer Inst 2007, 99:1095-1106.
8. Marxer E.E., Brussler J., Becker A., Schummelfeder J., Schubert R., Nimsky C., et al. Development and characterization of new nanoscaled ultrasound active lipid dispersions as contrast agents. Eur J Pharm Biopharm 2011, 77:430-437.
9. Xing Z., Wang J., Ke H., Zhao B., Yue X., Dai Z., et al. The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. Nanotechnology 2010, 10.1088/0957-4484/21/14/145607.
10. Krupka T.M., Solorio L., Wilson R.E., Wu H., Azar N., Exner A.A. Formulation and characterization of echogenic lipid-pluronic nanobubbles. Mol Pharm 2010, 7:49-59.
11. Wang Y., Li X., Zhou Y., Huang P., Xu Y. Preparation of nanobubbles for ultrasound imaging and intracellular drug delivery. Int J Pharm 2010, 384:148-153.
12. Weller Gregory ER., Wong Michael KK., Modzelewski Ruth A. Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine. Cancer Res 2005, 65:533-539.
13. Stieger S.M., Dayton P.A., Borden M.A., Caskey C.F., Griffey S.M., Wisner E.R., et al. Imaging of angiogenesis using cadence contrast pulse sequencing and targeted contrast agents. Contrast Media Mol Imaging 2008, 3:9-18.
14. Gao J., Chen K., Miao Z., Ren G., Chen X., Gambhir S.S., et al. Affibody-based nanoprobes for HER2-expressing cell and tumor imaging. Biomaterials 2011, 32:2141-2148.
15. Xu J.S., Huang J., Qin R., Hinkle G.H., Povoski S.P., Martin E.W., et al. Synthesizing and binding dual-mode poly (lactic-co-glycolic acid) (PLGA) nanobubbles for cancer targeting and imaging. Biomaterials 2010, 31:1716-1722.
16. Colozza M., Sidoni A., Mosconi A.M., Cavaliere A., Bisagni G., Gori S., et al. HER2 overexpression as a predictive marker in a randomized trial comparing adjuvant cyclophosphamide/methotrexate/5-fluorouracil with epirubicin in patients with stage I/II breast cancer: long-term results. Clin Breast Cancer 2005, 6:253-259.
17. Menard S., Casalini P., Campiglio M., Pupa S., Agresti R., Tagliabue HER2 overexpression in various tumor types, focussing on its relationship to the development of invasive breast cancer. Ann Oncol 2001, 12(Suppl.1):S15-S19.
18. Carion O., Mahler B., Pons T., Dubertret B. Synthesis, encapsulation, purification and coupling of single quantum dots in phospholipid micelles for their use in cellular and invivo imaging. Nat Protoc 2007, 2:2383-2390.
19. Gao X., Yang L., Petros J.A., Marshall F.F., Simons J.W., Nie S. Invivo molecular and cellular imaging with quantum dots. Curr Opin Biotechnol 2005, 16:63-72.
20. Ito A., Ino K., Kobayashi T., Honda H. The effect of RGD peptide-conjugated magnetite cationic liposomes on cell growth and cell sheet harvesting. Biomaterials 2005, 26:6185-6193.
21. Verma A., Stellacci F. Effect of surface properties on nanoparticle-cell interactions. Small 2010, 6:12-21.
22. Lofblom J., Feldwisch J., Tolmachev V., Carlsson J., Stahl S., Frejd F.Y. Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications. FEBS Lett 2010, 584:2670-2680.
23. Alexis F., Basto P., Levy-Nissenbaum E., Radovic-Moreno A.F., Zhang L., Pridgen E., et al. HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy. ChemMedChem 2008, 3:1839-1843.
24. Binz H.K., Amstutz P., Pluckthun A. Engineering novel binding proteins from nonimmunoglobulin domains. Nat Biotechnol 2005, 23:1257-1268.
25. Nilsson F.Y., Tolmachev V. Affibody molecules: new protein domains for molecular imaging and targeted tumor therapy. Curr Opin Drug Discov Devel 2007, 10:167-175.
26. Tong H.P., Wang L.F., Guo Y.L., Li L., Fan X.Z., Ding J., et al. Preparation of protamine cationic nanobubbles and experimental study of their physical properties and invivo contrast enhancement. Ultrasound Med Biol 2013, 39:2147-2157.
27. Wu H., Rognin N.G., Krupka T.M., Solorio L., Yoshiara H., Guenette G., et al. Acoustic characterization and pharmacokinetic analyses of new nanobubble ultrasound contrast agents. Ultrasound Med Biol 2013, 39:2137-2146.
28. Kwon I.K., Lee S.C., Han B., Park K. Analysis on the current status of targeted drug delivery to tumors. JControl Release 2012, 164:108-114.
29. Hahn M.A., Singh A.K., Sharma P., Brown S.C., Moudgil B.M. Nanoparticles as contrast agents for in-vivo bioimaging: current status and future perspectives. Anal Bioanal Chem 2011, 399:3-27.
30. Rosen J.E., Chan L., Shieh D.B., Gu F.X. Iron oxide nanoparticles for targeted cancer imaging and diagnostics. Nanomedicine 2012, 8:275-290.
31. Gao Z., Kennedy A.M., Christensen D.A., Rapoport N.Y. Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy. Ultrasonics 2008, 48:260-270.
32. Gao J.H., Chen K., Xie R.G., Xie J., Yan Y.J., Cheng Z., et al. Invivo tumor-targeted fluorescence imaging using near-infrared non-cadmium quantum dots. Bioconjug Chem 2010, 21:604-609.