Deacetyl-mycoepoxydiene, isolated from plant endophytic fungi Phomosis sp. demonstrates anti-microtubule activity in MCF-7 cells

Biomedicine and Pharmacotherapy

Volumn 69, Issue , 2015, Pages 82-89

  Zhu, Shan Shan ^a   Zhang, Yu Sheng ^a   Sheng, Xie Huang ^a   Xu, Miao ^b   Wu, Si Si ^a,c   Shen, Yue Mao ^a   Huang, Yao Jian ^d   Wang, Yi ^e   Shi, Yan Qiu ^a  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF TORONTO   (Canada)

^c Hospital of the People's Liberation Army   (China)

^d XIAMEN UNIVERSITY   (China)

^e Xiwang Group Company Limited   (China)

Author keywords

Apoptosis; Cell cycle arrest; Microtubule inhibitor

Indexed keywords

ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; BETA ACTIN; CASPASE 3; CASPASE 9; DEACETYL MYCOEPOXYDIENE; NATURAL PRODUCT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; UNCLASSIFIED DRUG; BRIDGED COMPOUND; DEACETYL-MYCOEPOXYDIENE; FUSED HETEROCYCLIC RINGS; MYCOEPOXYDIENE; PYRONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER INHIBITION; CELL CULTURE; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; ENDOPHYTIC FUNGUS; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; MICROTUBULE ASSEMBLY; MITOSIS; MOUSE; NONHUMAN; PHOMOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL DEATH; CELL DIVISION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; ENDOPHYTE; FEMALE; FUNGUS; ISOLATION AND PURIFICATION; METABOLISM; MICROTUBULE; NUDE MOUSE; POLYMERIZATION;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BRIDGED COMPOUNDS; CELL CYCLE CHECKPOINTS; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPHYTES; FEMALE; FUNGI; G2 PHASE; HUMANS; MCF-7 CELLS; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULES; POLYMERIZATION; PYRONES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84922217515     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2014.11.020     Document Type: Article

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