Characterization of a novel Zn2+-dependent intrinsic imipenemase from Pseudomonas aeruginosa

Journal of Antimicrobial Chemotherapy

Volumn 69, Issue 11, 2014, Pages 2972-2978

  Fajardo, Alicia ^a,d   Hernando Amado, Sara ^a   Oliver, Antonio ^b   Ball, Geneviéve ^c   Filloux, Alain ^c,e   Martinez, Jose L ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITY OF SYDNEY   (Australia)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Carbapenemases; Intrinsic resistance; Metallo b lactamases; Resistome

Indexed keywords

AZTREONAM; BACTERIAL ENZYME; BETA LACTAMASE; CARBAPENEM; CEFEPIME; CEFOXITIN; CEFTAZIDIME; IMIPENEM; IMIPENEMASE; MEROPENEM; PIPERACILLIN; UNCLASSIFIED DRUG; ZINC ION; BACTERIAL PROTEIN; CARBAPENEM DERIVATIVE; ZINC;

AMPC GENE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENOME; BACTERIUM ISOLATE; ENZYME KINETICS; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SEQUENCE; MEXA GENE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPRD GENE; PA5542 GENE; PHYLOGENY; POXB GENE; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; REAL TIME POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; SYNTENY; WILD TYPE; DRUG EFFECTS; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM;

BACTERIAL PROTEINS; CARBAPENEMS; HUMANS; IMIPENEM; PSEUDOMONAS AERUGINOSA; ZINC;

EID: 84922195825     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku267     Document Type: Article

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