Neuroprotective Effects of Trans-Caryophyllene Against Kainic Acid Induced Seizure Activity and Oxidative Stress in Mice

Neurochemical Research

Volumn 40, Issue 1, 2015, Pages 118-123

  Liu, Hao ^a   Song, Zhi ^a   Liao, Daguang ^a   Zhang, Tianyi ^a   Liu, Feng ^a   Zhuang, Kai ^a   Luo, Kui ^a   Yang, Liang ^a  

^a THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Epilepsy; Inflammation; Kainic acid; Oxidative stress; Trans caryophyllene

Indexed keywords

CARYOPHYLLENE; CATALASE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 1BETA; KAINIC ACID; NEUROPROTECTIVE AGENT; SUPEROXIDE DISMUTASE; TRANS CARYOPHYLLENE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; ANTIOXIDANT; CYTOKINE; SESQUITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT THERAPY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN DAMAGE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; LIPID PEROXIDATION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SEIZURE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRAIN CHEMISTRY; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; SEIZURES;

ANIMALS; ANTIOXIDANTS; BRAIN CHEMISTRY; CYTOKINES; EXCITATORY AMINO ACID AGONISTS; KAINIC ACID; LIPID PEROXIDATION; MICE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; SEIZURES; SESQUITERPENES;

EID: 84922104157     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1474-0     Document Type: Article

References (20)

1. Simon RP, Greenberg DA, Aminof MJ (2009) Clinical neurology, 7th edn. McGraw-Hill, New York
2. Rao RS, Medhi B, Khanduja KL, Pandhi P (2010) Correlation of seizures and biochemical parameters of oxidative stress in experimentally induced inflammatory rat models. Fundam Clin Pharmacol 24(3):325–331
3. Gupta YK, Briyal S (2006) Protective effect of vineatrol against kainic acid induced seizures, oxidative stress and on the expression of heat shock proteins in rats. Eur Neuropsychopharmacol 16(2):85–91
4. Yalcin A, Kilinc E, Kocturk S, Resmi H, Sozmen EY (2004) Effect of melatonin cotreatment against kainic acid on coenzyme Q10, lipid peroxidation and Trx mRNA in rat hippocampus. Int J Neurosci 114(9):1085–1897
5. Choi IY, Ju C, Anthony Jalin AM et al (2013) Activation of cannabinoid CB2 receptor-mediated AMPK/CREB pathway reduces cerebral ischemic injury. Am J Pathol 182:928–939
6. Chang HJ, Kim HJ, Chun HS (2007) Quantitative structure-activity relationship (QSAR) for neuroprotective activity of terpenoids. Life Sci 80:835–841
7. Guo K, Mou X, Huang J, Xiong N, Li H (2014) Trans-caryophyllene suppresses hypoxia-induced neuroinflammatory responses by inhibiting NF-κB activation in microglia. J Mol Neurosci [Epub ahead of print]
8. Kim HJ, Chung JI, Lee SH, Jung YS, Moon CH, Baik EJ (2008) Involvement of endogenous prostaglandin F2alpha on kainic acid-induced seizure activity through FP receptor: the mechanism of proconvulsant effects of COX-2 inhibitors. Brain Res 1193:153–161
9. Souza MA, Oliveira MS, Furian AF, Rambo LM, Ribeiro LR, Lima FD, Dalla Corte LC, Silva LF, Retamoso LT, Dalla Corte CL, Puntel GO, de Avila DS, Soares FA, Fighera MR, de Mello CF, Royes LF (2009) Swimming training prevents pentylenetetrazol-induced inhibition of Na?, K?-ATPase activity, seizures, and oxidative stress. Epilepsia 50:811–823
10. Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X (2012) Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease. J Neurochem 120(3):419–429
11. Zhang XM, Zhu J (2011) Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines. Curr Neuropharmacol 9(2):388–398
12. Shin EJ, Jeong JH, Chung YH, Kim WK, Ko KH, Bach JH, Hong JS, Yoneda Y, Kim HC (2011) Role of oxidative stress in epileptic seizures. Neurochem Int 59:122–137
13. Wang Q, Xu J, Rottinghaus GE, Simonyi A, Lubahn D, Sun GY, Sun AY (2002) Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res 958:439–447
14. Wallace MJ, Martin BR, DeLorenzo RJ (2002) Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. Eur J Pharmacol 452:295–301
15. Marsicano G, Goodenough S, Monory K et al (2003) CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302:84–88
16. Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ (2003) The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. J Pharmacol Exp Ther 307:129–137
17. Gross DW, Hamm J, Ashworth NL, Quigley D (2004) Marijuana use and epilepsy: prevalence in patients of a tertiary care epilepsy center. Neurology 62:2095–2097
18. Goffin K, Bormans G, Casteels C et al (2008) An in vivo [18F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam. Neuropharmacology 54(7):1103–1106
19. Sinha S, Patil SA, Jayalekshmy V, Satishchandra P (2008) Do cytokines have any role in epilepsy? Epilepsy Res 82:171–176
20. Dube C, Vezzani A, Behrens M et al (2005) Interleukin-1beta contributes to the generation of experimental febrile seizures. Ann Neurol 57:152–155