Trans-caryophyllene suppresses hypoxia-induced neuroinflammatory responses by inhibiting NF-κB activation in microglia

Journal of Molecular Neuroscience

Volumn 54, Issue 1, 2014, Pages 41-48

  Guo, Kexin ^a   Mou, Xiaojie ^a   Huang, Jinsha ^a   Xiong, Nian ^a   Li, Hongge ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b NONE   (China)

Author keywords

Hypoxia; Inflammation; NF B; Trans Caryophyllene; Type 2 cannabinoid receptor (CB2R)

Indexed keywords

CARYOPHYLLENE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; CANNABINOID 2 RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; SESQUITERPENE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL HYPOXIA; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DRUG MECHANISM; LUCIFERASE ASSAY; MACROPHAGE ACTIVATION; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; RNA INTERFERENCE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM; MITOCHONDRION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL HYPOXIA; CELL LINE; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MICROGLIA; MITOCHONDRIA; NF-KAPPA B; REACTIVE OXYGEN SPECIES; RECEPTOR, CANNABINOID, CB2; SESQUITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84906333244     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0243-5     Document Type: Article

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