Nanogrooved substrate promotes direct lineage reprogramming offibroblasts to functional induced dopaminergic neurons

Biomaterials

Volumn 45, Issue , 2015, Pages 36-45

  Yoo, Junsang ^a   Noh, Myungkyung ^b   Kim, Hongnam ^b,c   Jeon, Noo Li ^b   Kim, Byung Soo ^b   Kim, Jongpil ^a  

^a Dongguk University   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

Direct reprogramming; Induced dopaminergic neurons; Mesenchymal to epithelial transition; Nanotopography

Indexed keywords

CELL CULTURE; FIBROBLASTS; NANOTECHNOLOGY; SUBSTRATES;

BIOPHYSICAL STIMULATION; DIRECT REPROGRAMMING; DOPAMINERGIC NEURONS; HISTONE MODIFICATION; MESENCHYMAL TO EPITHELIAL TRANSITIONS; NANOPATTERNED SUBSTRATES; NANOTOPOGRAPHIES; TRANSCRIPTIONAL CHANGES;

NEURONS;

AMINO ACID DECARBOXYLASE; BETA TUBULIN; CLAUDIN 3; DOPAMINE; EPITHELIAL CELL ADHESION MOLECULE; HISTONE H3; NANOPARTICLE; NOGGIN; NUCLEAR RECEPTOR RELATED FACTOR 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LMX1A; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR PITX3; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; UVOMORULIN; VESICULAR MONOAMINE TRANSPORTER 2; BIOLOGICAL MARKER; HISTONE; LYSINE; SCATTER FACTOR RECEPTOR;

ARTICLE; CELL LINEAGE; CELL STIMULATION; CELL STRUCTURE; CYTOARCHITECTURE; DOPAMINERGIC NERVE CELL; FIBROBLAST; GENE EXPRESSION; NUCLEAR REPROGRAMMING; PHENOTYPE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TOPOGRAPHY; ANIMAL; ANIMAL EMBRYO; CELL DIFFERENTIATION; CELL SHAPE; CHEMISTRY; CYTOLOGY; CYTOSKELETON; GENE EXPRESSION REGULATION; METABOLISM; METHYLATION; MOUSE;

ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SHAPE; CELLULAR REPROGRAMMING; CYTOSKELETON; DOPAMINERGIC NEURONS; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE EXPRESSION REGULATION; HISTONES; LYSINE; METHYLATION; MICE; NANOPARTICLES; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-MET;

EID: 84922042146     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.12.049     Document Type: Article

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