Recent advances in lymphatic targeted drug delivery system for tumor metastasis

Cancer Biology and Medicine

Volumn 11, Issue 4, 2014, Pages 247-254

  Zhang, Xiao Yu ^a   Lu, Wei Yue ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Liposome; Lymphatic metastatic tumor; Lymphatic system; Metastasis; Nanoparticle; Polymer micelle (PM); Targeted drug delivery system

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHEROYLOXY ACETIC ACID; ANTINEOPLASTIC AGENT; DOCETAXEL; DOXORUBICIN; DRUG CARRIER; LIPOSOME; NANOPARTICLE; PACLITAXEL; POLYMER; UNCLASSIFIED DRUG;

CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; DRUG DELIVERY SYSTEM; HUMAN; LYMPH NODE; LYMPH NODE METASTASIS; LYMPH VESSEL; LYMPH VESSEL METASTASIS; LYMPHATIC METASTATIC TUMOR; LYMPHOID TISSUE; MICELLE; NONHUMAN; PREDICTIVE VALUE; REVIEW; TUMOR CELL;

EID: 84921951075     PISSN: 20953941     EISSN: None     Source Type: Journal    
DOI: 10.7497/j.issn.2095-3941.2014.04.003     Document Type: Review

References (47)

1. Roberto S, Valeria B, Roberto del V, Raffaella M, Chiara FA, Leopoldo R. Analysis by high resolution ultrasound of superficial lymph nodes: anatomical, morphological and structural variations. Clin Imaging, 2014;38:96-99.
2. Xie Y, Bagby TR, Cohen MS, Forrest ML. Drug delivery to the lymphatic system: importance in future cancer diagnosis and therapies. Expert Opin Drug Deliv 2009;6:785-792.
3. Nishioka Y, Yoshino H. Lymphatic targeting with nanoparticulate system. Adv Drug Deliv Rev 2001;47:55-64.
4. Ran S, Volk L, Hall K, Flister MJ. Lymphangiogenesis and lymphatic metastasis in breast cancer. Pathophysiology 2010;17:229-251.
5. McAllaster JD, Cohen MS. Role of the lymphatics in cancer metastasis and chemotherapy applications. Adv Drug Deliv Rev 2011;63:867-875.
6. Rinderknecht M, Detmar M. Tumor lymphangiogenesis and melanoma metastasis. J Cell Physiol 2008;216:347-354.
7. Maby-El Hajjami H, Petrova TV. Developmental and pathological lymphangiogenesis: from models to human disease. Histochem Cell Biol 2008;130:1063-1078.
8. Mohrman DE, Heller LJ. eds. Cardiovascular Physiology, 6th Ed. New York: McGraw-Hill Companies, 2006.
9. Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, Butz S, et al. Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med 2007;204:2349-2362.
10. Cueni LN, Detmar M. New insights into the molecular control of the lymphatic vascular system and its role in disease. J Invest Dermatol 2006;126:2167-2177.
11. Cai S, Yang Q, Bagby TR, Forrest ML. Lymphatic drug delivery using engineered liposomes and solid lipid nanoparticles. Adv Drug Deliv Rev 2011;63:901-908.
12. Ali Khan A, Mudassir J, Mohtar N, Darwis Y. Advanced drug delivery to the lymphatic system: lipid-based nanoformulations. Int J Nanomedicine 2013;8:2733-2744.
13. Kerjaschki D. The lymphatic vasculature revisited. J Clin Invest 2014;124:874-877.
14. Yao M, Xiao H, McClements DJ. Delivery of lipophilic bioactives: assembly, disassembly, and reassembly of lipid nanoparticles. Annu Rev Food Sci Technol 2014;5:53-81.
15. Flanagan J, Singh H. Microemulsions: a potential delivery system for bioactives in food. Crit Rev Food Sci Nutr 2006;46:221-237.
16. Israelachvili JN. eds. Intermolecular and Surface Forces. 3rd Ed. London: Academic Press, 2011.
17. Berggreen E, Wiig H. Lymphatic function and responses in periodontal disease. Exp Cell Res 2014;325:130-137.
18. He XW, Liu T, Chen YX, Cheng DJ, Li XR, Xiao Y, et al. Calcium carbonate nanoparticle delivering vascular endothelial growth factor-C siRNA effectively inhibits lymphangiogenesis and growth of gastric cancer in vivo. Cancer Gene Ther 2008;15:193-202.
19. Laakkonen P, Porkka K, Hoffman JA, Ruoslahti E. A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat Med 2002;8:751-755.
20. Yan Z, Zhan C, Wen Z, Feng L, Wang F, Liu Y, et al. LyP-1-conjugated doxorubicin-loaded liposomes suppress lymphatic metastasis by inhibiting lymph node metastases and destroying tumor lymphatics. Nanotechnology 2011;22:415103.
21. Yang LZ, Sun L, Zhang YG. Distribution, migration and excretion of bio-inert nano-particles in vivo. Sheng Wu Ji Shu Tong Xun 2005;16:525-527 (in Chinese).
22. Singh I, Swami R, Khan W, Sistla R. Lymphatic system: a prospective area for advanced targeting of particulate drug carriers. Expert Opin Drug Deliv 2014;11:211-229.
23. Ling SS, Magosso E, Khan NA, Yuen KH, Barker SA. Enhanced oral bioavailability and intestinal lymphatic transport of a hydrophilic drug using liposomes. Drug Dev Ind Pharm 2006;32:335-345.
24. Latimer P, Menchaca M, Snyder RM, Yu W, Gilbert BE, Sanders BG, et al. Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases. Exp Biol Med (Maywood) 2009;234:1244-1252.
25. Yang XY, Li YX, Li M, Zhang L, Feng LX, Zhang N. Hyaluronic acid-coated nanostructured lipid carriers for targeting paclitaxel to cancer. Cancer Lett 2013;334:338-345.
26. Tiantian Y, Wenji Z, Mingshuang S, Rui Y, Shuangshuang S, Yuling M, et al. Study on intralymphatic-targeted hyaluronic acid-modified nanoliposome: influence of formulation factors on the lymphatic targeting. Int J Pharm 2014;471:245-257.
27. Oussoren C, Storm G. Liposomes to target the lymphatics by subcutaneous administration. Adv Drug Deliv Rev 2001;50:143-156.
28. Moghimi SM, Hawley AE, Christy NM, Gray T, Illum L, Davis SS. Surface engineered nanospheres with enhanced drainage into lymphatics and uptake by macrophages of the regional lymph nodes. FEBS Lett 1994;344:25-30.
29. Moghimi M, Moghimi SM. Lymphatic targeting of immuno-PEG-liposomes: evaluation of antibody-coupling procedures on lymph node macrophage uptake. J Drug Target 2008;16:586-590.
30. Moghimi SM. Modulation of lymphatic distribution of subcutaneously injected poloxamer 407-coated nanospheres: the effect of the ethylene oxide chain configuration. FEBS Lett 2003;540:241-244.
31. van Rooijen N. Liposomes for targeting of antigens and drugs: immunoadjuvant activity and liposome-mediated depletion of macrophages. J Drug Target 2008;16:529-534.
32. Feng L, Zhang L, Liu M, Yan Z, Wang C, Gu B, et al. Roles of dextrans on improving lymphatic drainage for liposomal drug delivery system. J Drug Target 2010;18:168-178.
33. Laakkonen P, Porkka K, Hoffman JA, Ruoslahti E. A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat Med 2002;8:751-755.
34. Laakkonen P, Akerman ME, Biliran H, Yang M, Ferrer F, Karpanen T, et al. Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. Proc Natl Acad Sci U S A 2004;101:9381-9386.
35. Fogal V, Zhang L, Krajewski S, Ruoslahti E. Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res 2008;68:7210-7218.
36. Tan R, Niu M, Zhao J, Liu Y, Feng N. Preparation of vincristine sulfate-loaded poly (butylcyanoacrylate) nanoparticles modified with pluronic F127 and evaluation of their lymphatic tissue targeting. J Drug Target 2014;22:509-517.
37. Fan L, Chen J, Zhang X, Liu Y, Xu C. Follicle-stimulating hormone polypeptide modified nanoparticle drug delivery system in the treatment of lymphatic metastasis during ovarian carcinoma therapy. Gynecol Oncol 2014;135:125-132.
38. Cai S, Thati S, Bagby TR, Diab HM, Davies NM, Cohen MS, et al. Localized doxorubicin chemotherapy with a biopolymeric nanocarrier improves survival and reduces toxicity in xenografts of human breast cancer. J Control Release 2010;146:212-218.
39. Luo G, Yu X, Jin C, Yang F, Fu D, Long J, et al. LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors. Int J Pharm 2010;385:150-156.
40. Laakkonen P, Zhang L, Ruoslahti E. Peptide targeting of tumor lymph vessels. Ann N Y Acad Sci 2008;1131:37-43.
41. Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv Drug Deliv Rev 2001;47:113-131.
42. Nishiyama N, Kataoka K. Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther 2006;112:630-648.
43. Cabral H, Kataoka K. Progress of drug-loaded polymeric micelles into clinical studies. J Control Release 2014;190:465-476.
44. Reddy ST, van der Vlies AJ, Simeoni E, Angeli V, Randolph GJ, O'Neil CP, et al. Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat Biotechnol 2007;25:1159-1164.
45. Cabral H, Matsumoto Y, Mizuno K, Chen Q, Murakami M, Kimura M, et al. Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 2011;6:815-823.
46. Wang J, Wang Y, Liang W. Delivery of drugs to cell membranes by encapsulation in PEG-PE micelles. J Control Release 2012;160:637-651.
47. Li Y, Jin M, Shao S, Huang W, Yang F, Chen W, et al. Small-sized polymeric micelles incorporating docetaxel suppress distant metastases in the clinically-relevant 4T1 mouse breast cancer model. BMC Cancer 2014;14:329.