Liposomes for targeting of antigens and drugs: Immunoadjuvant activity and liposome-mediated depletion of macrophages

Journal of Drug Targeting

Volumn 16, Issue 7-8, 2008, Pages 529-534

  Van Rooijen, Nico ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Clodronate; Immunoadjuvant; Liposomes; Macrophages

Indexed keywords

ANTIGEN; CALCIUM; CHEMOKINE; CLODRONIC ACID; CYTOKINE; DRUG CARRIER; IMMUNOLOGICAL ADJUVANT; LIPOSOME; MACROGOL; MONOCLONAL ANTIBODY; PHOSPHOLIPASE; PHOSPHOLIPID;

APOPTOSIS; ARTICLE; BONE DISEASE; CELL ENCAPSULATION; CELL MEMBRANE TRANSPORT; CONCENTRATION (PARAMETERS); DEPLETION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG RELEASE; DRUG TARGETING; DRUG TRANSPORT; HUMAN; HYDROPHILICITY; IMMUNOREACTIVITY; INTRACELLULAR SPACE; LIPOSOMAL GENE DELIVERY SYSTEM; MACROPHAGE; NONHUMAN; PHAGOCYTE; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; SPLEEN; SUICIDE GENE THERAPY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS; CLODRONIC ACID; DRUG DELIVERY SYSTEMS; LIPOSOMES; MACROPHAGES;

EID: 49149084340     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860802228426     Document Type: Article

References (33)

1. Allison, AC and Gregoriadis, G. (1974) Liposomes as immunological adjuvants. Nature, 252, p. 252.
2. Bangham, AD (1993) Liposomes, The Babraham connection. Chem Phys Lipids, 64, pp. 275-285.
3. Barbe, E., Huitinga, I., Dopp, EA, Bauer, J. and Dijkstra, CD (1996) A novel bone marrow frozen section assay for studying hematopoietic interactions in situ: The role of stromal bone marrow macrophages in erythroblast binding. J Cell Sci, 109, pp. 2937-2945.
4. Barrera, P., Blom, A., Van Lent, PLEM, Van Bloois, L., Storm, G., Beijnen, J., van Rooijen, N., Van De Putte, LBA and Van Den Berg, WB (2000) Synovial macrophage depletion with clodronate containing liposomes in rheumatoid arthritis. Arthritis Rheum, 43, pp. 1951-1959.
5. Bergh, A., Damber, J-E and van Rooijen, N. (1993) Liposome-mediated macrophage depletion: An experimental approach to study the role of testicular macrophages. J Endocrinol, 136, pp. 407-413.
6. Biewenga, J., Van der Ende, B., Krist, LFG, Borst, A., Ghufron, M. and van Rooijen, N. (1995) Macrophage depletion and repopulation in the rat after i.p. administration of Cl2MBP-liposomes: Depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of Freund's adjuvant. Cell Tissue Res, 280, pp. 189-196.
7. Claassen, I., van Rooijen, N. and Claassen, E. (1990) A new method for removal of mononuclear phagocytes from heterogenous cell populations 'in vitro', using the liposome-mediated macrophage 'suicide' technique. J Immunol Meth, 134, pp. 153-161.
8. Delemarre, FGA, Kors, N., Kraal, G. and van Rooijen, N. (1990) Repopulation of macrophages in popliteal lymph nodes of mice after liposome mediated depletion. J Leuk Biol, 47, pp. 251-257.
9. Gregoriadis, G. (1977) Targeting of drugs. Nature, 265, pp. 407-411.
10. Gregoriadis, G. (1990) Immunological adjuvants: A role for liposomes. Immunol Today, 11, pp. 89-97.
11. Gregoriadis, G. (1995) Engineering liposomes for drug delivery: Progress and problems. Trends Biotechnol, 13, pp. 527-537.
12. Leenen, PJM, Radosevic, K., Voerman, JSA, Salomon, B., van Rooijen, N., Klatzmann, D. and Van Ewijk, W. (1998) Heterogeneity of mouse spleen dendritic cells: In vivo phagocytic activity, expression of macrophage markers and subpopulation turnover. J Immunol, 160, pp. 2166-2173.
13. Litzinger, DC, Buiting, AMJ, van Rooijen, N. and Huang, L. (1994) Effect of liposome size on the circulation time and intraorgan distribution of amphipathic polyethylene-glycol containing liposomes. Biochim Biophys Acta, 1190, pp. 99-107.
14. Marin-Teva, JL, Dusart, I., Colin, C., Gervais, A., van Rooijen, N. and Mallat, M. (2004) Microglia promote the death of developing purkinje cells. Neuron, 41, pp. 535-547.
15. Polfliet, MMJ, Goede, PH, Van Kesteren-Hendrikx, EML, van Rooijen, N., Dijkstra, CD and Van den Berg, TK (2001) A method for the selective depletion of perivascular and meningeal macrophages in the central nervous system. J Neuroimmunol, 116, pp. 188-195.
16. Su, D. and van Rooijen, N. (1989) The role of macrophages in the immunoadjuvant action of liposomes: Effects of elimination of splenic macrophages on the immune response against intravenously injected liposome associated albumin antigen. Immunology, 66, pp. 466-470.
17. Sunderkotter, C., Nikolic, T., Dillon, MJ, van Rooijen, N., Stehling, M., Drevets, DA and Leenen, PJM (2004) Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol, 172, pp. 4410-4417.
18. Thepen, T., van Rooijen, N. and Kraal, G. (1989) Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune responses in mice. J Exp Med, 170, pp. 499-509.
19. Van Lent, PLEM, Van De Hoek, A., Van Den Bersselaar, L, Spanjaards, MFR, van Rooijen, N., Dijkstra, CD, Van De Putte, LBA and Van Den Berg, WB (1993) In vivo role of phagocytic synovial lining cells in onset of experimental arthritis. Am J Pathol, 143, pp. 1226-1237.
20. Van Lent, PLEM, Holthuyzen, AEM, Van Den Bersselaar, LAM, van Rooijen, N., Joosten, LAB, Van De Loo, FAJ, Van De Putte, LBA and Van Den Berg, WB (1996) Phagocytic lining cells determine local expression of inflammation in collagen type II arthritis. Arthritis Rheum, 39, pp. 1545-1555.
21. van Rooijen, N. and Van Nieuwmegen, R. (1980) Liposomes in immunology: Evidence that their adjuvant effect results from surface exposition of the antigens. Cellular Immunol, 49, pp. 402-407.
22. van Rooijen, N. and Van Nieuwmegen, R. (1984) Elimination of phagocytic cells in the spleen after intravenous injection of liposome encapsulated dichloromethylene-diphosphonate. An enzyme-histochemical study. Cell Tissue Res, 238, pp. 355-358.
23. van Rooijen, N. (1989) The liposome mediated macrophage 'suicide' technique. J Immunol Meth, 124, pp. 1-6.
24. van Rooijen, N., Kors, N. and Kraal, G. (1989) Macrophage subset repopulation in the spleen: Differential kinetics after liposome-mediated elimination. J Leuk Biol, 45, pp. 97-104.
25. van Rooijen, N. (1990) Antigen processing and presentation in vivo: The microenvironment as a crucial factor. Immunol Today, 11, pp. 436-439.
26. van Rooijen, N., Ter Hart, H, Kraal, G., Kors, N. and Claassen, E. (1992) Monoclonal antibody mediated targeting of enzymes. A comparative study using the mouse spleen as a model system. J Immunol Meth, 151, pp. 149-155.
27. van Rooijen, N. (1993) Extracellular and intracellular action of clodronate in osteolytic bone diseases: A hypothesis. Calcif Tiss Intern, 52, pp. 407-410.
28. van Rooijen, N. and Sanders, A. (1994) Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications. J Immunol Meth, 174, pp. 83-93.
29. van Rooijen, N. and Sanders, A. (1996) Kupffer cell depletion by liposome-delivered drugs: Comparative activity of intracellular clodronate, propamidine and ethylenediaminetetraacetic acid (EDTA). Hepatology, 23, pp. 1239-1243.
30. van Rooijen, N., Sanders, A. and Van den Berg, TK (1996) Apoptosis of macrophages induced by liposome-mediated intracellular delivery of drugs. J Immunol Meth, 193, pp. 93-99.
31. van Rooijen, N. and Sanders, A. (1997) Elimination, blocking and activation of macrophages: Three of a kind?. J Leuk Biol, 62, pp. 702-709.
32. van Rooijen, N., Bakker, J. and Sanders, A. (1997) Transient suppression of macrophage functions by liposome encapsulated drugs. Trends Biotechnol, 15, pp. 178-185.
33. van Rooijen, N. and Van Kesteren-Hendrikx, E. (2002) Clodronate liposomes: Perspectives in research and therapeutics. J Liposome Res, 12, pp. 81-94.