Fundamental analysis of recombinant human epidermal growth factor in solution with biophysical methods

Drug Development and Industrial Pharmacy

Volumn 41, Issue 2, 2015, Pages 300-306

  Kim, Nam Ah ^a   Lim, Dae Gon ^a   Lim, Jun Yeul ^a   Kim, Ki Hyun ^a   Jeong, Seong Hoon ^a  

^a Dongguk University   (South Korea)

Author keywords

Biophysical analysis; FT IR; pH; Recombinant human epidermal growth factor; Thermodynamic stability

Indexed keywords

4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; CITRIC ACID; GAMMA UROGASTRONE; HISTIDINE; PHOSPHATE; TROMETAMOL; BUFFER; EPIDERMAL GROWTH FACTOR; PROTEIN AGGREGATE; RECOMBINANT PROTEIN; SOLUTION AND SOLUBILITY;

ARTICLE; BETA SHEET; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG STABILITY; INFRARED SPECTROSCOPY; ISOELECTRIC POINT; LIGHT SCATTERING; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PROTEIN AGGREGATION; PROTEIN CONTENT; PROTEIN STABILITY; TEMPERATURE; THERMODYNAMICS; ZETA POTENTIAL; BIOPHYSICS; CHEMICAL MODEL; CHEMISTRY; HUMAN; LIGHT; MEDICINAL CHEMISTRY; PROTEIN SECONDARY STRUCTURE; RADIATION SCATTERING; SOLUTION AND SOLUBILITY;

BIOPHYSICAL PHENOMENA; BUFFERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; EPIDERMAL GROWTH FACTOR; HUMANS; HYDROGEN-ION CONCENTRATION; LIGHT; MODELS, CHEMICAL; PARTICLE SIZE; PROTEIN AGGREGATES; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SCATTERING, RADIATION; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS;

EID: 84921928391     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.859152     Document Type: Article

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