메뉴 건너뛰기




Volumn 46, Issue 3, 2015, Pages 1039-1050

Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma

Author keywords

EGFR; Lung squamous cell carcinoma; MET; MicroRNA; MiR 206; Receptor tyrosine kinase; Tumor suppressor

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; MICRORNA; MICRORNA 206; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; MET PROTEIN, HUMAN; MIRN206 MICRORNA, HUMAN;

EID: 84921908873     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2802     Document Type: Article
Times cited : (44)

References (44)
  • 2
    • 80455123686 scopus 로고    scopus 로고
    • Pathology of lung cancer
    • Travis WD: Pathology of lung cancer. Clin Chest Med 32: 669-692, 2011.
    • (2011) Clin Chest Med , vol.32 , pp. 669-692
    • Travis, W.D.1
  • 3
    • 84883013481 scopus 로고    scopus 로고
    • Management of non-small-cell lung cancer: Recent developments
    • Reck M, Heigener DF, Mok T, Soria JC and Rabe KF: Management of non-small-cell lung cancer: recent developments. Lancet 382: 709-719, 2013.
    • (2013) Lancet , vol.382 , pp. 709-719
    • Reck, M.1    Heigener, D.F.2    Mok, T.3    Soria, J.C.4    Rabe, K.F.5
  • 4
    • 2342591455 scopus 로고    scopus 로고
    • The discovery of receptor tyrosine kinases: Targets for cancer therapy
    • Gschwind A, Fischer OM and Ullrich A: The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer 4: 361-370, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 361-370
    • Gschwind, A.1    Fischer, O.M.2    Ullrich, A.3
  • 5
    • 0026510966 scopus 로고
    • Receptor tyrosine kinases
    • Cadena DL and Gill GN: Receptor tyrosine kinases. FASEB J 6: 2332-2337, 1992.
    • (1992) FASEB J , vol.6 , pp. 2332-2337
    • Cadena, D.L.1    Gill, G.N.2
  • 6
    • 33746864060 scopus 로고    scopus 로고
    • The role of the ErbB family members in non-small cell lung cancers sensitive to epidermal growth factor receptor kinase inhibitors
    • Engelman JA and Cantley LC: The role of the ErbB family members in non-small cell lung cancers sensitive to epidermal growth factor receptor kinase inhibitors. Clin Cancer Res 12: S4372-S4376, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. S4372-S4376
    • Engelman, J.A.1    Cantley, L.C.2
  • 8
    • 84904756821 scopus 로고    scopus 로고
    • Management of acquired resistance to epidermal growth factor receptor kinase inhibitors in patients with advanced non-small cell lung cancer
    • Sacher AG, Janne PA and Oxnard GR: Management of acquired resistance to epidermal growth factor receptor kinase inhibitors in patients with advanced non-small cell lung cancer. Cancer 120: 2289-2298, 2014.
    • (2014) Cancer , vol.120 , pp. 2289-2298
    • Sacher, A.G.1    Janne, P.A.2    Oxnard, G.R.3
  • 9
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, Zejnullahu K, Mitsudomi T, et al: MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316: 1039-1043, 2007.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 10
    • 38049150665 scopus 로고    scopus 로고
    • MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    • Bean J, Brennan C, Shih JY, et al: MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci USA 104: 20932-20937, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20932-20937
    • Bean, J.1    Brennan, C.2    Shih, J.Y.3
  • 11
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 12
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors andmicroRNAs
    • Hobert O: Gene regulation by transcription factors andmicroRNAs. Science 319: 1785-1786, 2008.
    • (2008) Science , vol.319 , pp. 1785-1786
    • Hobert, O.1
  • 13
    • 73349125465 scopus 로고    scopus 로고
    • MicroRNAs in cancer: Small molecules with a huge impact
    • Iorio MV and Croce CM: MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol 27: 5848-5856, 2009.
    • (2009) J Clin Oncol , vol.27 , pp. 5848-5856
    • Iorio, M.V.1    Croce, C.M.2
  • 14
    • 84907170770 scopus 로고    scopus 로고
    • Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer
    • Rolfo C, Fanale D, Hong DS, et al: Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer. Curr Pharm Biotechnol 15: 475-485, 2014.
    • (2014) Curr Pharm Biotechnol , vol.15 , pp. 475-485
    • Rolfo, C.1    Fanale, D.2    Hong, D.S.3
  • 15
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz W, Bhattacharyya SN and Sonenberg N: Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9: 102-114, 2008.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 16
    • 69249088165 scopus 로고    scopus 로고
    • MicroRNAs: Critical mediators of differentiation, development and disease
    • Friedman JM and Jones PA: MicroRNAs: critical mediators of differentiation, development and disease. Swiss Med Wkly. 139: 466-472, 2009.
    • (2009) Swiss Med Wkly , vol.139 , pp. 466-472
    • Friedman, J.M.1    Jones, P.A.2
  • 17
    • 84863013767 scopus 로고    scopus 로고
    • Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma
    • Moriya Y, Nohata N, Kinoshita T, et al: Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma. J Hum Genet 57: 38-45, 2012.
    • (2012) J Hum Genet , vol.57 , pp. 38-45
    • Moriya, Y.1    Nohata, N.2    Kinoshita, T.3
  • 18
    • 34548457234 scopus 로고    scopus 로고
    • The IASLC Lung Cancer Staging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
    • Goldstraw P, Crowley J, Chansky K, et al: The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2: 706-714, 2007.
    • (2007) J Thorac Oncol , vol.2 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3
  • 19
    • 84856454111 scopus 로고    scopus 로고
    • Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer
    • Kojima S, Chiyomaru T, Kawakami K, et al: Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. Br J Cancer 106: 405-413, 2012.
    • (2012) Br J Cancer , vol.106 , pp. 405-413
    • Kojima, S.1    Chiyomaru, T.2    Kawakami, K.3
  • 20
    • 84877081955 scopus 로고    scopus 로고
    • Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma
    • Nohata N, Hanazawa T, Kinoshita T, et al: Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma. Br J Cancer 108: 1648-1658, 2013.
    • (2013) Br J Cancer , vol.108 , pp. 1648-1658
    • Nohata, N.1    Hanazawa, T.2    Kinoshita, T.3
  • 21
    • 84887848486 scopus 로고    scopus 로고
    • Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma
    • Kinoshita T, Nohata N, Hnasawa T, et al: Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma. Br J Cancer 109: 2636-2645, 2013.
    • (2013) Br J Cancer , vol.109 , pp. 2636-2645
    • Kinoshita, T.1    Nohata, N.2    Hnasawa, T.3
  • 22
    • 79952280500 scopus 로고    scopus 로고
    • The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer
    • Yoshino H, Chiyomaru T, Enokida H, et al: The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. Br J Cancer 104: 808-818, 2011.
    • (2011) Br J Cancer , vol.104 , pp. 808-818
    • Yoshino, H.1    Chiyomaru, T.2    Enokida, H.3
  • 23
    • 84905011727 scopus 로고    scopus 로고
    • Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib ± onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit
    • Koeppen H, Yu W, Zha J, et al: Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib ± onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit. Clin Cancer Res 20: 4488-4498, 2014.
    • (2014) Clin Cancer Res , vol.20 , pp. 4488-4498
    • Koeppen, H.1    Yu, W.2    Zha, J.3
  • 24
    • 84895531936 scopus 로고    scopus 로고
    • The microRNA expression signature of bladder cancer by deep sequencing: The functional significance of the miR-195/497 cluster
    • Itesako T, Seki N, Yoshino H, et al: The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster. PLoS One 9: e84311, 2014.
    • (2014) PLoS One , vol.9
    • Itesako, T.1    Seki, N.2    Yoshino, H.3
  • 25
    • 84861905586 scopus 로고    scopus 로고
    • Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma
    • Hidaka H, Seki N, Yoshino H, et al: Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma. Oncotarget 3: 44-57, 2012.
    • (2012) Oncotarget , vol.3 , pp. 44-57
    • Hidaka, H.1    Seki, N.2    Yoshino, H.3
  • 26
    • 84860011976 scopus 로고    scopus 로고
    • microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers
    • Nohata N, Hanazawa T, Enokida H and Seki N: microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers. Oncotarget 3: 9-21, 2012.
    • (2012) Oncotarget , vol.3 , pp. 9-21
    • Nohata, N.1    Hanazawa, T.2    Enokida, H.3    Seki, N.4
  • 27
    • 84894030999 scopus 로고    scopus 로고
    • MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D
    • Georgantas R, Streicher K, Greenless L, et al: MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D. Pigment Cell Melanoma Res 27: 275-286, 2014.
    • (2014) Pigment Cell Melanoma Res , vol.27 , pp. 275-286
    • Georgantas, R.1    Streicher, K.2    Greenless, L.3
  • 28
    • 77953289017 scopus 로고    scopus 로고
    • MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas
    • Missiaglia E, Shepherd C.J, Patel S, et al: MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas. Br J Cancer 102: 1769-1777, 2010.
    • (2010) Br J Cancer , vol.102 , pp. 1769-1777
    • Missiaglia, E.1    Shepherd, C.J.2    Patel, S.3
  • 29
    • 70350383632 scopus 로고    scopus 로고
    • MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development
    • Yan D, Dong Xda E, Chen X, et al: MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. J Biol Chem 284: 29596-29604, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 29596-29604
    • Yan, D.1    Dong Xda, E.2    Chen, X.3
  • 30
    • 82355191732 scopus 로고    scopus 로고
    • Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERalpha-positive endometrioid adenocarcinoma
    • Chen X, Yan Q, Li S, et al: Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERalpha-positive endometrioid adenocarcinoma. Cancer Lett 314: 41-53, 2012.
    • (2012) Cancer Lett , vol.314 , pp. 41-53
    • Chen, X.1    Yan, Q.2    Li, S.3
  • 31
    • 48549099077 scopus 로고    scopus 로고
    • miR-206 expression is down-regulated in estrogen receptor alpha-positive human breast cancer
    • Kondo N, Toyama T, Sugiura H, et al: miR-206 expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res 68: 5004-5008, 2008.
    • (2008) Cancer Res , vol.68 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3
  • 32
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Maemondo M, Inoue A, Kobayashi K, et al: Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 362: 2380-2388, 2010.
    • (2010) N Engl J Med , vol.362 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 33
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
    • Zhou C, Wu YL, Chen G, et al: Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 12: 735-742, 2011.
    • (2011) Lancet Oncol , vol.12 , pp. 735-742
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3
  • 34
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, et al: Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol 12: 1004-1012, 2011.
    • (2011) Lancet Oncol , vol.12 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3
  • 35
    • 84881542709 scopus 로고    scopus 로고
    • The emerging role of MET/HGF inhibitors in oncology
    • Scagliotti GV, Novello S and von Pawel J: The emerging role of MET/HGF inhibitors in oncology. Cancer Treat Rev 39: 793-801, 2013.
    • (2013) Cancer Treat Rev , vol.39 , pp. 793-801
    • Scagliotti, G.V.1    Novello, S.2    Von Pawel, J.3
  • 36
    • 84891834273 scopus 로고    scopus 로고
    • High coexpression of both EGFR and IGF1R correlates with poor patient prognosis in resected non-small-cell lung cancer
    • Gately K, Forde L, Cuffe S, et al: High coexpression of both EGFR and IGF1R correlates with poor patient prognosis in resected non-small-cell lung cancer. Clin Lung Cancer 15: 58-66, 2014.
    • (2014) Clin Lung Cancer , vol.15 , pp. 58-66
    • Gately, K.1    Forde, L.2    Cuffe, S.3
  • 37
    • 84898922599 scopus 로고    scopus 로고
    • The Met receptor tyrosine kinase: A key player in oncogenesis and drug resistance
    • Maroun CR and Rowlands T: The Met receptor tyrosine kinase: a key player in oncogenesis and drug resistance. Pharmacol Ther 142: 316-338, 2014.
    • (2014) Pharmacol Ther , vol.142 , pp. 316-338
    • Maroun, C.R.1    Rowlands, T.2
  • 38
    • 84875914687 scopus 로고    scopus 로고
    • MET as a possible target for non-small-cell lung cancer
    • Sadiq AA and Salgia R: MET as a possible target for non-small-cell lung cancer. J Clin Oncol 31: 1089-1096, 2013.
    • (2013) J Clin Oncol , vol.31 , pp. 1089-1096
    • Sadiq, A.A.1    Salgia, R.2
  • 40
    • 57749089758 scopus 로고    scopus 로고
    • Down-regulation of micro-RNA-1 (miR-1)in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
    • Nasser MW, Datta J, Nuovo G, et al: Down-regulation of micro-RNA-1 (miR-1)in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J Biol Chem 283: 33394-33405, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 33394-33405
    • Nasser, M.W.1    Datta, J.2    Nuovo, G.3
  • 41
    • 68849118992 scopus 로고    scopus 로고
    • The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation
    • Taulli R, Bersani F, Foglizzo V, et al: The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. J Clin Invest 119: 2366-2378, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 2366-2378
    • Taulli, R.1    Bersani, F.2    Foglizzo, V.3
  • 42
    • 45549089973 scopus 로고    scopus 로고
    • microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma
    • Kefas B, Godlewski J, Comeau L, et al: microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 68: 3566-3572, 2008.
    • (2008) Cancer Res , vol.68 , pp. 3566-3572
    • Kefas, B.1    Godlewski, J.2    Comeau, L.3
  • 43
    • 76749152907 scopus 로고    scopus 로고
    • miR-146a suppresses invasion of pancreatic cancer cells
    • Li Y, Vandenboom TG II, Wang Z, et al: miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res 70: 1486-1495, 2010.
    • (2010) Cancer Res , vol.70 , pp. 1486-1495
    • Li, Y.1    Vandenboom, T.G.2    Wang, Z.3
  • 44
    • 84878133983 scopus 로고    scopus 로고
    • Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2
    • Acunzo M, Romano G, Palmieri D, et al: Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2. Proc Natl Acad Sci USA 110: 8573-8578, 2013.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 8573-8578
    • Acunzo, M.1    Romano, G.2    Palmieri, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.