Mechanistic analysis of the role of bromodomain-containing protein 4 (BRD4) in BRD4-NUT oncoprotein-induced transcriptional activation

Journal of Biological Chemistry

Volumn 290, Issue 5, 2015, Pages 2744-2758

  Wang, Ranran ^a   You, Jianxin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CHEMICAL ACTIVATION; PROTEINS; TRANSCRIPTION;

DOMINANT NEGATIVE; FUSION PROTEINS; GENE TRANSCRIPTIONS; HYPERACETYLATION; MECHANISTIC ANALYSIS; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL REGULATION; TRANSGENE EXPRESSION;

NUTS (FASTENERS);

BROMODOMAIN CONTAINING PROTEIN 4; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; HISTONE ACETYLTRANSFERASE; NUCLEAR PROTEIN IN TESTIS; ONCOPROTEIN; UNCLASSIFIED DRUG; BRD4 PROTEIN, HUMAN; BRD4-NUT FUSION ONCOGENE PROTEIN, HUMAN; E1A ASSOCIATED P300 PROTEIN; EP300 PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN; CONTROLLED STUDY; GENE ACTIVATION; GENE CONSTRUCT; GENE LOCUS; GENE REPRESSION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HISTONE HYPERACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SINGLE CELL ANALYSIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSGENE; U2OS CELL LINE; CHROMATIN IMMUNOPRECIPITATION; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; E1A-ASSOCIATED P300 PROTEIN; HUMANS; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84921906969     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.600759     Document Type: Article

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