Synthesis of a phosphoantigen prodrug that potently activates Vγ9Vδ2 T-lymphocytes

Chemistry and Biology

Volumn 21, Issue 8, 2014, Pages 945-954

  Hsiao, Chia Hung Christine ^a   Lin, Xiaochen ^a   Barney, Rocky J ^b,c   Shippy, Rebekah R ^b   Li, Jin ^a   Vinogradova, Olga ^a   Wiemer, David F ^b,d   Wiemer, Andrew J ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b The University of Iowa   (United States)

^c Western Wyoming Community College   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXY 3 METHYL BUT 2 ENYLPYROPHOSPHATE; ANTIGEN; PEPTIDES AND PROTEINS; PHOSPHOANTIGEN; PIVALOYLOXYMETHYL; PRODRUG; PROTEIN BUTYROPHILIN 3A1; RYANODINE RECEPTOR; SPROUTY PROTEIN; UNCLASSIFIED DRUG; ORGANOPHOSPHATE;

ARTICLE; BINDING AFFINITY; BLOOD CELL; CELL STIMULATION; CYTOLYSIS; DAUDI CELL LINE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; T LYMPHOCYTE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; T LYMPHOCYTE SUBPOPULATION;

CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LYMPHOCYTE ACTIVATION; MOLECULAR STRUCTURE; ORGANOPHOSPHATES; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTE SUBSETS;

EID: 84921894883     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.06.006     Document Type: Article

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