메뉴 건너뛰기




Volumn 130, Issue 2, 2015, Pages 130-136

Trimetazidine pretreatment inhibits myocardial apoptosis and improves cardiac function in a swine model of coronary microembolization

Author keywords

Apoptosis; Caspase; Coronary microembolization; Trimetazidine

Indexed keywords

CASPASE 3; CASPASE 9; TRIMETAZIDINE; VASODILATOR AGENT;

EID: 84921890260     PISSN: 00086312     EISSN: 14219751     Source Type: Journal    
DOI: 10.1159/000369246     Document Type: Article
Times cited : (21)

References (36)
  • 2
    • 0034620537 scopus 로고    scopus 로고
    • Recognition of the importance of embolization in atherosclerotic vascular disease
    • Topol EJ, Yadav JS: Recognition of the importance of embolization in atherosclerotic vascular disease. Circulation 2000; 101: 570-580.
    • (2000) Circulation , vol.101 , pp. 570-580
    • Topol, E.J.1    Yadav, J.S.2
  • 3
    • 0033809487 scopus 로고    scopus 로고
    • Angiographic no-reflow phenomenon as a predictor of adverse long-term outcome in patients treated with percutaneous transluminal coronary angioplasty for first acute myocardial infarction
    • Morishima I, Sone T, Okumura K, Tsuboi H, Kondo J, Mukawa H, Matsui H, Toki Y, Ito T, Hayakawa T: Angiographic no-reflow phenomenon as a predictor of adverse long-term outcome in patients treated with percutaneous transluminal coronary angioplasty for first acute myocardial infarction. J Am Coll Cardiol 2000; 36: 1202-1209.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1202-1209
    • Morishima, I.1    Sone, T.2    Okumura, K.3    Tsuboi, H.4    Kondo, J.5    Mukawa, H.6    Matsui, H.7    Toki, Y.8    Ito, T.9    Hayakawa, T.10
  • 5
    • 80052618441 scopus 로고    scopus 로고
    • Cardiomyocyte apoptosis and death receptor pathway in a rat model of coronary microembolization (in Chinese)
    • Li L, Su Q, Wang Y, Su B, Dai RX, Lu YG, Wu XH, Liu TW: Cardiomyocyte apoptosis and death receptor pathway in a rat model of coronary microembolization (in Chinese). Zhonghua Xin Xue Guan Bing Za Zhi 2010; 38: 363-368.
    • (2010) Zhonghua Xin Xue Guan Bing Za Zhi , vol.38 , pp. 363-368
    • Li, L.1    Su, Q.2    Wang, Y.3    Su, B.4    Dai, R.X.5    Lu, Y.G.6    Wu, X.H.7    Liu, T.W.8
  • 6
    • 84879946021 scopus 로고    scopus 로고
    • Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats
    • Su Q, Li L, Liu YC, Zhou Y, Lu YG, Wen WM: Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats. Exp Clin Cardiol 2013; 18: 161-165.
    • (2013) Exp Clin Cardiol , vol.18 , pp. 161-165
    • Su, Q.1    Li, L.2    Liu, Y.C.3    Zhou, Y.4    Lu, Y.G.5    Wen, W.M.6
  • 7
    • 70149089344 scopus 로고    scopus 로고
    • Granulocyte colony stimulating factor attenuated myocardial apoptosis via Janus kinase 2/signal transducer and activator of transcription signal transduction pathway in rats with coronary microembolization (in Chinese)
    • Zhang FL, Chen LL, Li SM, Wang WW: Granulocyte colony stimulating factor attenuated myocardial apoptosis via Janus kinase 2/signal transducer and activator of transcription signal transduction pathway in rats with coronary microembolization (in Chinese). Zhonghua Xin Xue Guan Bing Za Zhi 2008; 36: 254-259.
    • (2008) Zhonghua Xin Xue Guan Bing Za Zhi , vol.36 , pp. 254-259
    • Zhang, F.L.1    Chen, L.L.2    Li, S.M.3    Wang, W.W.4
  • 9
    • 82055200582 scopus 로고    scopus 로고
    • Efficacy comparison of trimetazidine with therapeutic alternatives in stable angina pectoris: A network meta-analysis
    • Danchin N, Marzilli M, Parkhomenko A, Ribeiro JP: Efficacy comparison of trimetazidine with therapeutic alternatives in stable angina pectoris: a network meta-analysis. Cardiology 2011; 120: 59-72.
    • (2011) Cardiology , vol.120 , pp. 59-72
    • Danchin, N.1    Marzilli, M.2    Parkhomenko, A.3    Ribeiro, J.P.4
  • 10
    • 79952117897 scopus 로고    scopus 로고
    • Evaluation of the myocardial protection of trimetazidine during percutaneous coronary intervention: A multi-center randomized and controlled clinical study (in Chinese)
    • Chen YD, Zhao LK, Tian F, Du ZM, Jiang H, Wei M: Evaluation of the myocardial protection of trimetazidine during percutaneous coronary intervention: a multi-center randomized and controlled clinical study (in Chinese). Zhonghua Nei Ke Za Zhi 2010; 49: 473-476.
    • (2010) Zhonghua Nei Ke Za Zhi , vol.49 , pp. 473-476
    • Chen, Y.D.1    Zhao, L.K.2    Tian, F.3    Du, Z.M.4    Jiang, H.5    Wei, M.6
  • 11
    • 34249283806 scopus 로고    scopus 로고
    • Protective effect of an acute oral loading dose of trimetazidine on myocardial injury following percutaneous coronary intervention
    • Bonello L, Sbragia P, Amabile N, Com O, Pierre SV, Levy S, Paganelli F: Protective effect of an acute oral loading dose of trimetazidine on myocardial injury following percutaneous coronary intervention. Heart 2007; 93: 703-707.
    • (2007) Heart , vol.93 , pp. 703-707
    • Bonello, L.1    Sbragia, P.2    Amabile, N.3    Com, O.4    Pierre, S.V.5    Levy, S.6    Paganelli, F.7
  • 12
    • 84863665293 scopus 로고    scopus 로고
    • Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation
    • Zhou X, Li C, Xu W, Chen J: Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation. PLoS One 2012; 7:e40424.
    • (2012) PLoS One , vol.7 , pp. e40424
    • Zhou, X.1    Li, C.2    Xu, W.3    Chen, J.4
  • 13
    • 77951080081 scopus 로고    scopus 로고
    • Trimetazidine, administered at the onset of reperfusion, ameliorates myocardial dysfunction and injury by activation of p38 mitogen-activated protein kinase and Akt signaling
    • Khan M, Meduru S, Mostafa M, Khan S, Hideg K, Kuppusamy P: Trimetazidine, administered at the onset of reperfusion, ameliorates myocardial dysfunction and injury by activation of p38 mitogen-activated protein kinase and Akt signaling. J Pharmacol Exp Ther 2010; 333: 421-429.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 421-429
    • Khan, M.1    Meduru, S.2    Mostafa, M.3    Khan, S.4    Hideg, K.5    Kuppusamy, P.6
  • 14
    • 33847051689 scopus 로고    scopus 로고
    • Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion
    • Ruixing Y, Wenwu L, Al-Ghazali R: Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion. Transl Res 2007; 149: 152-160.
    • (2007) Transl Res , vol.149 , pp. 152-160
    • Ruixing, Y.1    Wenwu, L.2    Al-Ghazali, R.3
  • 15
    • 84903874434 scopus 로고    scopus 로고
    • The involvement of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in the regulation of inflammation following coronary microembolization
    • Wang J, Li L, Su Q, Zhou Y, Chen H, Ma G, Liu T, Tang Z, Liu Y: The involvement of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in the regulation of inflammation following coronary microembolization. Cell Physiol Biochem 2014; 33: 1963-1974.
    • (2014) Cell Physiol Biochem , vol.33 , pp. 1963-1974
    • Wang, J.1    Li, L.2    Su, Q.3    Zhou, Y.4    Chen, H.5    Ma, G.6    Liu, T.7    Tang, Z.8    Liu, Y.9
  • 18
    • 0033940215 scopus 로고    scopus 로고
    • Coronary microembolization
    • Erbel R, Heusch G: Coronary microembolization. J Am Coll Cardiol 2000; 36: 22-24.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 22-24
    • Erbel, R.1    Heusch, G.2
  • 21
    • 80955166082 scopus 로고    scopus 로고
    • Effect of atorvastatin (Lipitor) on myocardial apoptosis and caspase-8 activation following coronary microembolization
    • Li L, Su Q, Wang Y, Dai R, Lu Y, Su B, Zhao Y: Effect of atorvastatin (Lipitor) on myocardial apoptosis and caspase-8 activation following coronary microembolization. Cell Biochem Biophys 2011; 61: 399-406.
    • (2011) Cell Biochem Biophys , vol.61 , pp. 399-406
    • Li, L.1    Su, Q.2    Wang, Y.3    Dai, R.4    Lu, Y.5    Su, B.6    Zhao, Y.7
  • 23
    • 0034678082 scopus 로고    scopus 로고
    • The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase
    • Kantor PF, Lucien A, Kozak R, Lopaschuk GD: The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res 2000; 86: 580-588.
    • (2000) Circ Res , vol.86 , pp. 580-588
    • Kantor, P.F.1    Lucien, A.2    Kozak, R.3    Lopaschuk, G.D.4
  • 24
    • 84904249140 scopus 로고    scopus 로고
    • Impact of trimetazidine on incidence of myocardial injury and contrast-induced nephropathy in diabetic patients with renal dysfunction undergoing elective percutaneous coronary intervention
    • Shehata M: Impact of trimetazidine on incidence of myocardial injury and contrast-induced nephropathy in diabetic patients with renal dysfunction undergoing elective percutaneous coronary intervention. Am J Cardiol 2014; 114: 389-394.
    • (2014) Am J Cardiol , vol.114 , pp. 389-394
    • Shehata, M.1
  • 25
    • 84883244403 scopus 로고    scopus 로고
    • The impact of trimetazidine treatment on left ventricular functions and plasma brain natriuretic peptide levels in patients with non-ST segment elevation myocardial infarction undergoing percutaneous coronary intervention
    • Demirelli S, Karakelleoglu S, Gundogdu F, Tas MH, Kaya A, Duman H, Degirmenci H, Hamur H, Simsek Z: The impact of trimetazidine treatment on left ventricular functions and plasma brain natriuretic peptide levels in patients with non-ST segment elevation myocardial infarction undergoing percutaneous coronary intervention. Korean Circ J 2013; 43: 462-467.
    • (2013) Korean Circ J , vol.43 , pp. 462-467
    • Demirelli, S.1    Karakelleoglu, S.2    Gundogdu, F.3    Tas, M.H.4    Kaya, A.5    Duman, H.6    Degirmenci, H.7    Hamur, H.8    Simsek, Z.9
  • 26
    • 33645753553 scopus 로고    scopus 로고
    • Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts
    • Gambert S, Vergely C, Filomenko R, Moreau D, Bettaieb A, Opie LH, Rochette L: Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts. Mol Cell Biochem 2006; 283: 147-152.
    • (2006) Mol Cell Biochem , vol.283 , pp. 147-152
    • Gambert, S.1    Vergely, C.2    Filomenko, R.3    Moreau, D.4    Bettaieb, A.5    Opie, L.H.6    Rochette, L.7
  • 27
    • 27644492930 scopus 로고    scopus 로고
    • Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury
    • Argaud L, Gomez L, Gateau-Roesch O, Couture-Lepetit E, Loufouat J, Robert D, Ovize M: Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury. J Mol Cell Cardiol 2005; 39: 893-899.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 893-899
    • Argaud, L.1    Gomez, L.2    Gateau-Roesch, O.3    Couture-Lepetit, E.4    Loufouat, J.5    Robert, D.6    Ovize, M.7
  • 28
    • 0035181640 scopus 로고    scopus 로고
    • Apoptosis in the ischemic reperfused myocardium
    • Holleyman CR, Larson DF: Apoptosis in the ischemic reperfused myocardium. Perfusion 2001; 16: 491-502.
    • (2001) Perfusion , vol.16 , pp. 491-502
    • Holleyman, C.R.1    Larson, D.F.2
  • 30
    • 0036187036 scopus 로고    scopus 로고
    • Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
    • Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, Akey CW: Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell 2002; 9: 423-432.
    • (2002) Mol Cell , vol.9 , pp. 423-432
    • Acehan, D.1    Jiang, X.2    Morgan, D.G.3    Heuser, J.E.4    Wang, X.5    Akey, C.W.6
  • 31
    • 77956908962 scopus 로고    scopus 로고
    • Regulation of the Apaf-1-caspase-9 apoptosome
    • Bratton SB, Salvesen GS: Regulation of the Apaf-1-caspase-9 apoptosome. J Cell Sci 2010; 123: 3209-3214.
    • (2010) J Cell Sci , vol.123 , pp. 3209-3214
    • Bratton, S.B.1    Salvesen, G.S.2
  • 32
    • 58449133203 scopus 로고    scopus 로고
    • Pathways involved in testicular germ cell apoptosis induced by H 2 O 2 in vitro
    • Maheshwari A, Misro MM, Aggarwal A, Sharma RK, Nandan D: Pathways involved in testicular germ cell apoptosis induced by H 2 O 2 in vitro. FEBS J 2009; 276: 870-881.
    • (2009) FEBS J , vol.276 , pp. 870-881
    • Maheshwari, A.1    Misro, M.M.2    Aggarwal, A.3    Sharma, R.K.4    Nandan, D.5
  • 34
    • 16244379567 scopus 로고    scopus 로고
    • Caspase-3 inhibition preserves myocardial geometry and long-term function after infarction
    • Balsam LB, Kofidis T, Robbins RC: Caspase-3 inhibition preserves myocardial geometry and long-term function after infarction. J Surg Res 2005; 124: 194-200.
    • (2005) J Surg Res , vol.124 , pp. 194-200
    • Balsam, L.B.1    Kofidis, T.2    Robbins, R.C.3
  • 35
    • 68649088611 scopus 로고    scopus 로고
    • Protective effects of caspase-9 and poly(ADP-ribose) polymerase inhibitors on ischemia-reperfusion-induced myocardial injury
    • Sodhi RK, Singh M, Singh N, Jaggi AS: Protective effects of caspase-9 and poly(ADP-ribose) polymerase inhibitors on ischemia-reperfusion-induced myocardial injury. Arch Pharm Res 2009; 32: 1037-1043.
    • (2009) Arch Pharm Res , vol.32 , pp. 1037-1043
    • Sodhi, R.K.1    Singh, M.2    Singh, N.3    Jaggi, A.S.4
  • 36
    • 84923530831 scopus 로고    scopus 로고
    • Lentivirus mediated interference of caspase-3 expression ameliorates the heart function on rats with acute myocardial infarction
    • Liu Q: Lentivirus mediated interference of caspase-3 expression ameliorates the heart function on rats with acute myocardial infarction. Eur Rev Med Pharmacol Sci 2014; 18: 1852-1858.
    • (2014) Eur Rev Med Pharmacol Sci , vol.18 , pp. 1852-1858
    • Liu, Q.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.