Interaction of Aβ peptide with tubulin causes an inhibition of tubulin polymerization and the apoptotic death of cancer cells

Chemical Communications

Volumn 51, Issue 12, 2015, Pages 2249-2252

  Saha, Abhijit ^a   Mohapatra, Saswat ^a   Kurkute, Prashant ^a   Jana, Batakrishna ^a   Mondal, Prasenjit ^a   Bhunia, Debmalya ^a   Ghosh, Subhajit ^a   Ghosh, Surajit ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; TUBULIN; VINBLASTINE; BUB1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PEPTIDE; PROTEIN BINDING; PROTEIN MAD2; PROTEIN P53; PROTEIN SERINE THREONINE KINASE;

A549 CELL LINE; APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL; FLUORESCENCE ACTIVATED CELL SORTING; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MCF 7 CELL LINE; MICROTUBULE ASSEMBLY; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; TUBULIN POLYMERIZATION ASSAY; CHEMISTRY; METABOLISM; POLYMERIZATION; TUMOR CELL LINE;

AMYLOID BETA-PEPTIDES; APOPTOSIS; BINDING SITES; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GUANOSINE TRIPHOSPHATE; HELA CELLS; HUMANS; MAD2 PROTEINS; MCF-7 CELLS; PEPTIDES; POLYMERIZATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; TUBULIN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84921853164     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c4cc09390a     Document Type: Article

References (29)

1. (a) C. M. Roe, M. I. Behrens, C. Xiong, J. P. Miller and J. C. Morris, Neurology, 2005, 64, 895;
2. (b) M. I. Behrens, C. Lendon and C. M. Roe, Curr. Alzheimer Res., 2009, 3, 196.
3. (a) J. Hardy, Neuron, 2006, 52, 3;
4. (b) C. J. Barrow and M. G. Zagorski, Science, 1991, 253, 179;
5. (c) G. G. Glenner and C. W. Wong, Biochem. Biophys. Res. Commun., 1984, 120, 885.
6. D. Hanahan and R. A. Weinberg, Cell, 2000, 100, 57.
7. J. A. Driver, A. Beiser, R. Au, B. E. Kreger, L. G. Splansky, T. Kurth, D. P. Kiel, P. K. Lu, S. Seshadri and P. A. Wolf, BMJ, 2012, 344, e1442.
8. I. Sponne, A. Fifre, B. Drouet, C. Klein, V. Koziel, M. P. Raymond, J. Olivier, J. Chambaz and T. Pillot, J. Biol. Chem., 2003, 278, 3437.
9. (a) A. G. Henriques, S. I. Vieira, E. F. C. e Silva and O. A. B. C. e Silva, J. Neurochem., 2010, 113, 761;
10. (b) S. I. Borysov, A. Granic, J. Padmanabhan, C. E. Walczak and H. Potter, Cell Cycle, 2011, 10, 1397.
11. (a) H. Zhao, J. Zhu, K. Cui, X. Xu, M. O'Brien, K. K. Wong, S. Kesari, W. Xia and S. T. C. Wong, Cancer Cell Int., 2009, 9, 1;
12. (b) D. Paris, N. Ganey, M. Banasiak, V. Laporte, N. Patel, M. Mullan, S. F. Murphy, B. C. Gi-Taek Yee, C. Ganey, D. Beaulieu-Abdelahad, V. S. Mathura, S. Brem and M. Mullan, J. Neurosci., 2010, 30, 11251;
13. (c) D. Paris, K. Townsend, A. Quadros, J. Humphrey, J. Sun, S. Brem, M. Wotoczek-Obadia, A. Delle Donne, N. Patel, D. F. Obregon, R. Crescentini, L. Abdullah, D. Coppola, A. M. Rojiani, F. Crawford, S. M. Sebti and M. Mullan, Angiogenesis, 2004, 7, 75.
14. (a) G. Gevorkian, A. Gonzalez-Noriega, G. Acero, J. Ordoñez, C. Michalak, M. E. Munguia, T. Govezensky, D. H. Cribbs and K. Manoutcharian, Neurochem. Int., 2008, 52, 1030;
15. (b) M. E. King, H. M. Kan, P. W. Baas, A. Erisir, C. G. Glabe and G. S. Bloom, J. Cell Biol., 2006, 175, 541;
16. (c) C. Ari, S. I. Borysov, J. Wu, J. Padmanabhan and H. Potter, Neurobiol. Aging, 2014, 8, 1839.
17. S. Arora, X. I. Wang, S. M. Keenan, C. Andaya, Q. Zhang, Y. Peng and W. J. Welsh, Cancer Res., 2009, 69, 1910.
18. (a) K. Nieznanski, Z. A. Podlubnaya and H. Nieznanska, Biochem. Biophys. Res. Commun., 2006, 349, 391;
19. (b) K. Gupta and D. Panda, Biochemistry, 2002, 41, 13029.
20. A. Biswas, A. Saha, B. Jana, P. Kurkute, G. Mondal and S. Ghosh, ChemBioChem, 2013, 14, 689.
21. (a) D. Bonne, C. Heusele, C. Simon and D. Pantaloni, J. Biol. Chem., 1985, 260, 2819;
22. (b) J. G. Ghosh, S. A. Houck and J. I. Clark, PLoS One, 2007, 2, e498.
23. (a) W. Qiang, W. M. Yau, Y. Luo, M. P. Mattson and R. Tycko, Proc. Natl. Acad. Sci. U. S. A., 2012, 109, 4443;
24. (b) S. Vivekanandan, R. J. Brender, Y. S. Lee and A. Ramamoorthy, Biochem. Biophys. Res. Commun., 2011, 411, 312;
25. (c) B. Gigant, C. Wang, R. B. G. Ravelli, F. Roussi, M. O. Steinmetz, P. A. Curmi, A. Sobel and M. Knossow, Nature, 2005, 435, 519.
26. (a) B. Bhattacharyya and J. Wolff, Proc. Natl. Acad. Sci. U. S. A. , 1976, 73, 2375;
27. (b) S. S. Rai and J. Wolff, Eur. J. Biochem., 1997, 250, 425;
28. (c) R. H. Chen, J. Cell Biol., 2002, 158, 487;
29. (d) D. A. Skoufias, P. R. Andreassen, F. B. Lacroix, L. Wilson and R. L. Margolis, Proc. Natl. Acad. Sci. U. S. A., 2001, 98, 4492.