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Volumn 35, Issue 3, 2015, Pages 573-579

Wnt16 Attenuates TGFβ-Induced Chondrogenic Transformation in Vascular Smooth Muscle

Author keywords

Chondrogenesis; Mouse; Muscle; Notch protein; Smooth; TGF beta; Vascular; Vascular calcification; Wnt16 protein

Indexed keywords

NOTCH RECEPTOR; OSTEOCALCIN; PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT16 PROTEIN; CALCIUM BINDING PROTEIN; MATRIX GLA PROTEIN; SCLEROPROTEIN; TGFB1 PROTEIN, MOUSE; TGFB3 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3; WNT PROTEIN; WNT16 PROTEIN, HUMAN; WNT16 PROTEIN, MOUSE;

EID: 84921829325     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.304393     Document Type: Article
Times cited : (26)

References (48)
  • 1
    • 1942486773 scopus 로고    scopus 로고
    • Osteogenic regulation of vascular calcification: An early perspective
    • Vattikuti R, Towler DA. Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab. 2004;286:E686-E696. doi: 10.1152/ajpendo.00552.2003.
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , pp. E686-E696
    • Vattikuti, R.1    Towler, D.A.2
  • 2
    • 0030947025 scopus 로고    scopus 로고
    • Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
    • Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature. 1997;386:78-81. doi: 10.1038/386078a0.
    • (1997) Nature , vol.386 , pp. 78-81
    • Luo, G.1    Ducy, P.2    McKee, M.D.3    Pinero, G.J.4    Loyer, E.5    Behringer, R.R.6    Karsenty, G.7
  • 3
    • 2942631661 scopus 로고    scopus 로고
    • Extracellular matrix mineralization is regulated locally; different roles of two GLA-containing proteins
    • Murshed M, Schinke T, McKee MD, Karsenty G. Extracellular matrix mineralization is regulated locally; different roles of two GLA-containing proteins. J Cell Biol. 2004;165:625-630. doi: 10.1083/jcb.200402046.
    • (2004) J Cell Biol , vol.165 , pp. 625-630
    • Murshed, M.1    Schinke, T.2    McKee, M.D.3    Karsenty, G.4
  • 6
    • 80052174320 scopus 로고    scopus 로고
    • The regulation of valvular and vascular sclerosis by osteogenic morphogens
    • Boström KI, Rajamannan NM, Towler DA. The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circ Res. 2011;109:564-577. doi: 10.1161/CIRCRESAHA.110.234278.
    • (2011) Circ Res , vol.109 , pp. 564-577
    • Boström, K.I.1    Rajamannan, N.M.2    Towler, D.A.3
  • 7
    • 83655167174 scopus 로고    scopus 로고
    • Transglutaminase 2-mediated activation of beta-catenin signaling has a critical role in warfarin-induced vascular calcification
    • Beazley KE, Deasey S, Lima F, Nurminskaya MV. Transglutaminase 2-mediated activation of beta-catenin signaling has a critical role in warfarin-induced vascular calcification. Arterioscler Thromb Vasc Biol. 2012;32:123-130.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 123-130
    • Beazley, K.E.1    Deasey, S.2    Lima, F.3    Nurminskaya, M.V.4
  • 8
    • 79956333162 scopus 로고    scopus 로고
    • Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells
    • Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M. Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells. J Biol Chem. 2011;286:19138-19148. doi: 10.1074/jbc.M110.175786.
    • (2011) J Biol Chem , vol.286 , pp. 19138-19148
    • Shimizu, T.1    Tanaka, T.2    Iso, T.3    Matsui, H.4    Ooyama, Y.5    Kawai-Kowase, K.6    Arai, M.7    Kurabayashi, M.8
  • 9
    • 47749145337 scopus 로고    scopus 로고
    • Targeting intercellular signals for bone regeneration from bone marrow mesenchymal progenitors
    • Long F. Targeting intercellular signals for bone regeneration from bone marrow mesenchymal progenitors. Cell Cycle. 2008;7:2106-2111.
    • (2008) Cell Cycle , vol.7 , pp. 2106-2111
    • Long, F.1
  • 10
    • 80051531363 scopus 로고    scopus 로고
    • Notch signaling: Simplicity in design, versatility in function
    • Andersson ER, Sandberg R, Lendahl U. Notch signaling: simplicity in design, versatility in function. Development. 2011;138:3593-3612. doi: 10.1242/dev.063610.
    • (2011) Development , vol.138 , pp. 3593-3612
    • Andersson, E.R.1    Sandberg, R.2    Lendahl, U.3
  • 11
    • 0031730268 scopus 로고    scopus 로고
    • Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo
    • Grainger DJ, Metcalfe JC, Grace AA, Mosedale DE. Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo. J Cell Sci. 1998;111 (pt 19):2977-2988.
    • (1998) J Cell Sci , vol.111 , pp. 2977-2988
    • Grainger, D.J.1    Metcalfe, J.C.2    Grace, A.A.3    Mosedale, D.E.4
  • 12
    • 33745962708 scopus 로고    scopus 로고
    • Molecular mechanisms of vascular calcification: Lessons learned from the aorta
    • Shao JS, Cai J, Towler DA. Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol. 2006;26:1423-1430. doi: 10.1161/01.ATV.0000220441.42041.20.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1423-1430
    • Shao, J.S.1    Cai, J.2    Towler, D.A.3
  • 13
    • 33745911180 scopus 로고    scopus 로고
    • Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease
    • Mathew S, Davies M, Lund R, Saab G, Hruska KA. Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease. Eur J Clin Invest. 2006;36(suppl 2):43-50. doi: 10.1111/j.1365-2362.2006.01663.x.
    • (2006) Eur J Clin Invest , vol.36 , pp. 43-50
    • Mathew, S.1    Davies, M.2    Lund, R.3    Saab, G.4    Hruska, K.A.5
  • 14
    • 36148995515 scopus 로고    scopus 로고
    • Regulation of in vitro vascular calcification by BMP4, VEGF and Wnt3a
    • Mikhaylova L, Malmquist J, Nurminskaya M. Regulation of in vitro vascular calcification by BMP4, VEGF and Wnt3a. Calcif Tissue Int. 2007;81:372-381. doi: 10.1007/s00223-007-9073-6.
    • (2007) Calcif Tissue Int. , vol.81 , pp. 372-381
    • Mikhaylova, L.1    Malmquist, J.2    Nurminskaya, M.3
  • 17
    • 84884789599 scopus 로고    scopus 로고
    • Attenuation of chondrogenic transformation in vascular smooth muscle by dietary quercetin in the MGP-deficient mouse model
    • Beazley KE, Lima F, Borras T, Nurminskaya M. Attenuation of chondrogenic transformation in vascular smooth muscle by dietary quercetin in the MGP-deficient mouse model. PLoS One. 2013;8:e76210. doi: 10.1371/ journal.pone.0076210.
    • (2013) PLoS One , vol.8 , pp. e76210
    • Beazley, K.E.1    Lima, F.2    Borras, T.3    Nurminskaya, M.4
  • 18
    • 84879123915 scopus 로고    scopus 로고
    • Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells
    • Cheng SL, Shao JS, Behrmann A, Krchma K, Towler DA. Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells. Arterioscler Thromb Vasc Biol. 2013;33:1679-1689. doi: 10.1161/ATVBAHA.113.300647.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1679-1689
    • Cheng, S.L.1    Shao, J.S.2    Behrmann, A.3    Krchma, K.4    Towler, D.A.5
  • 19
    • 84861966392 scopus 로고    scopus 로고
    • Notch signalling in smooth muscle cells during development and disease
    • Fouillade C, Monet-Leprêtre M, Baron-Menguy C, Joutel A. Notch signalling in smooth muscle cells during development and disease. Cardiovasc Res. 2012;95:138-146. doi: 10.1093/cvr/cvs019.
    • (2012) Cardiovasc Res , vol.95 , pp. 138-146
    • Fouillade, C.1    Monet-Leprêtre, M.2    Baron-Menguy, C.3    Joutel, A.4
  • 21
    • 67650334134 scopus 로고    scopus 로고
    • Notch signaling induces osteogenic differentiation and mineralization of vascular smooth muscle cells: Role of Msx2 gene induction via Notch-RBP-Jk signaling
    • Shimizu T, Tanaka T, Iso T, Doi H, Sato H, Kawai-Kowase K, Arai M, Kurabayashi M. Notch signaling induces osteogenic differentiation and mineralization of vascular smooth muscle cells: role of Msx2 gene induction via Notch-RBP-Jk signaling. Arterioscler Thromb Vasc Biol. 2009;29:1104-1111. doi: 10.1161/ATVBAHA.109.187856.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1104-1111
    • Shimizu, T.1    Tanaka, T.2    Iso, T.3    Doi, H.4    Sato, H.5    Kawai-Kowase, K.6    Arai, M.7    Kurabayashi, M.8
  • 22
    • 70350580660 scopus 로고    scopus 로고
    • Notch1 represses osteogenic pathways in aortic valve cells
    • Nigam V, Srivastava D. Notch1 represses osteogenic pathways in aortic valve cells. J Mol Cell Cardiol. 2009;47:828-834. doi: 10.1016/j. yjmcc.2009.08.008.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 828-834
    • Nigam, V.1    Srivastava, D.2
  • 23
    • 61349101373 scopus 로고    scopus 로고
    • Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation
    • Witte F, Dokas J, Neuendorf F, Mundlos S, Stricker S. Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009;9:215-223. doi: 10.1016/j.gep.2008.12.009.
    • (2009) Gene Expr Patterns , vol.9 , pp. 215-223
    • Witte, F.1    Dokas, J.2    Neuendorf, F.3    Mundlos, S.4    Stricker, S.5
  • 24
    • 4644276225 scopus 로고    scopus 로고
    • Wnt/betacatenin signaling is sufficient and necessary for synovial joint formation
    • Guo X, Day TF, Jiang X, Garrett-Beal L, Topol L, Yang Y. Wnt/betacatenin signaling is sufficient and necessary for synovial joint formation. Genes Dev. 2004;18:2404-2417. doi: 10.1101/gad.1230704.
    • (2004) Genes Dev , vol.18 , pp. 2404-2417
    • Guo, X.1    Day, T.F.2    Jiang, X.3    Garrett-Beal, L.4    Topol, L.5    Yang, Y.6
  • 25
    • 37249040479 scopus 로고    scopus 로고
    • The role of the perichondrium in fetal bone development
    • Kronenberg HM. The role of the perichondrium in fetal bone development. Ann N Y Acad Sci. 2007;1116:59-64. doi: 10.1196/annals.1402.059.
    • (2007) Ann N Y Acad Sci , vol.1116 , pp. 59-64
    • Kronenberg, H.M.1
  • 26
    • 84888027280 scopus 로고    scopus 로고
    • Variation in the Kozak sequence of WNT16 results in an increased translation and is associated with osteoporosis related parameters
    • Hendrickx G, Boudin E, Fija?kowski I, Nielsen TL, Andersen M, Brixen K, Van Hul W. Variation in the Kozak sequence of WNT16 results in an increased translation and is associated with osteoporosis related parameters. Bone. 2014;59:57-65. doi: 10.1016/j.bone.2013.10.022.
    • (2014) Bone , vol.59 , pp. 57-65
    • Hendrickx, G.1    Boudin, E.2    Fijakowski, I.3    Nielsen, T.L.4    Andersen, M.5    Brixen, K.6    Van Hul, W.7
  • 27
    • 79958290042 scopus 로고    scopus 로고
    • A somitic Wnt16/Notch pathway specifies haematopoietic stem cells
    • Clements WK, Kim AD, Ong KG, Moore JC, Lawson ND, Traver D. A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature. 2011;474:220-224. doi: 10.1038/nature10107.
    • (2011) Nature , vol.474 , pp. 220-224
    • Clements, W.K.1    Kim, A.D.2    Ong, K.G.3    Moore, J.C.4    Lawson, N.D.5    Traver, D.6
  • 28
    • 77954105508 scopus 로고    scopus 로고
    • Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis
    • Speer MY, Li X, Hiremath PG, Giachelli CM. Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis. J Cell Biochem. 2010;110:935-947. doi: 10.1002/jcb.22607.
    • (2010) J Cell Biochem , vol.110 , pp. 935-947
    • Speer, M.Y.1    Li, X.2    Hiremath, P.G.3    Giachelli, C.M.4
  • 29
    • 84886653153 scopus 로고    scopus 로고
    • Two sides of MGP null arterial disease: Chondrogenic lesions dependent on transglutaminase 2 and elastin fragmentation associated with induction of adipsin
    • Beazley KE, Reckard S, Nurminsky D, Lima F, Nurminskaya M. Two sides of MGP null arterial disease: chondrogenic lesions dependent on transglutaminase 2 and elastin fragmentation associated with induction of adipsin. J Biol Chem. 2013;288:31400-31408. doi: 10.1074/jbc. M113.495556.
    • (2013) J Biol Chem , vol.288 , pp. 31400-31408
    • Beazley, K.E.1    Reckard, S.2    Nurminsky, D.3    Lima, F.4    Nurminskaya, M.5
  • 30
    • 0029100688 scopus 로고
    • Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1
    • Denker AE, Nicoll SB, Tuan RS. Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1. Differentiation. 1995;59:25-34. doi: 10.1046/j.1432-0436.1995.5910025.x.
    • (1995) Differentiation , vol.59 , pp. 25-34
    • Denker, A.E.1    Nicoll, S.B.2    Tuan, R.S.3
  • 32
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptorlike kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman GJ, Nicolás FJ, Callahan JF, Harling JD, Gaster LM, Reith AD, Laping NJ, Hill CS. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptorlike kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol. 2002;62:65-74.
    • (2002) Mol Pharmacol , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolás, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6    Laping, N.J.7    Hill, C.S.8
  • 33
    • 84879528782 scopus 로고    scopus 로고
    • Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II
    • Dituri F, Mazzocca A, Peidrò FJ, Papappicco P, Fabregat I, De Santis F, Paradiso A, Sabbà C, Giannelli G. Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II. PLoS One. 2013;8:e67109. doi: 10.1371/journal.pone.0067109.
    • (2013) PLoS One , Issue.8 , pp. e67109
    • Dituri, F.1    Mazzocca, A.2    Peidrò, F.J.3    Papappicco, P.4    Fabregat, I.5    De Santis, F.6    Paradiso, A.7    Sabbà, C.8    Giannelli, G.9
  • 34
    • 33645893493 scopus 로고    scopus 로고
    • Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures
    • Fujimaki R, Toyama Y, Hozumi N, Tezuka K. Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures. J Bone Miner Metab. 2006;24:191-198. doi: 10.1007/s00774-005-0671-y.
    • (2006) J Bone Miner Metab , vol.24 , pp. 191-198
    • Fujimaki, R.1    Toyama, Y.2    Hozumi, N.3    Tezuka, K.4
  • 35
    • 77955981880 scopus 로고    scopus 로고
    • Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats
    • Neven E, Persy V, Dauwe S, De Schutter T, De Broe ME, D'Haese PC. Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats. Arterioscler Thromb Vasc Biol. 2010;30:1741-1750. doi: 10.1161/ATVBAHA.110.204834.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1741-1750
    • Neven, E.1    Persy, V.2    Dauwe, S.3    De Schutter, T.4    De Broe, M.E.5    D'Haese, P.C.6
  • 37
    • 33745946837 scopus 로고    scopus 로고
    • Bone morphogenic protein-4 induces hypertension in mice: Role of noggin, vascular NADPH oxidases, and impaired vasorelaxation
    • Miriyala S, Gongora Nieto MC, Mingone C, Smith D, Dikalov S, Harrison DG, Jo H. Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation. Circulation. 2006;113:2818-2825. doi: 10.1161/ CIRCULATIONAHA.106.611822.
    • (2006) Circulation , vol.113 , pp. 2818-2825
    • Miriyala, S.1    Gongora Nieto, M.C.2    Mingone, C.3    Smith, D.4    Dikalov, S.5    Harrison, D.G.6    Jo, H.7
  • 39
    • 77950986580 scopus 로고    scopus 로고
    • Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells
    • Kurpinski K, Lam H, Chu J, Wang A, Kim A, Tsay E, Agrawal S, Schaffer DV, Li S. Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells. Stem Cells. 2010;28:734-742. doi: 10.1002/stem.319.
    • (2010) Stem Cells , vol.28 , pp. 734-742
    • Kurpinski, K.1    Lam, H.2    Chu, J.3    Wang, A.4    Kim, A.5    Tsay, E.6    Agrawal, S.7    Schaffer, D.V.8    Li, S.9
  • 44
    • 84863897868 scopus 로고    scopus 로고
    • Meta-analysis of genomewide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus
    • Medina-Gomez C, Kemp JP, Estrada K, et al. Meta-analysis of genomewide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet. 2012;8:e1002718. doi: 10.1371/journal.pgen.1002718.
    • (2012) PLoS Genet , vol.8 , pp. e1002718
    • Medina-Gomez, C.1    Kemp, J.P.2    Estrada, K.3
  • 45
    • 66249120015 scopus 로고    scopus 로고
    • Patterns of Wnt/Fzd/ LRP gene expression during embryonic hematopoiesis
    • Corrigan PM, Dobbin E, Freeburn RW, Wheadon H. Patterns of Wnt/Fzd/ LRP gene expression during embryonic hematopoiesis. Stem Cells Dev. 2009;18:759-772. doi: 10.1089/scd.2008.0270.
    • (2009) Stem Cells Dev , vol.18 , pp. 759-772
    • Corrigan, P.M.1    Dobbin, E.2    Freeburn, R.W.3    Wheadon, H.4


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