Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein

Blood

Volumn 125, Issue 5, 2015, Pages 860-868

  Bender, Markus ^a   Thon, Jonathan N ^a,b   Ehrlicher, Allen J ^c,d   Wu, Stephen ^a   Mazutis, Linas ^b,c,g   Deschmann, Emoke ^a,e   Sola Visner, Martha ^a   Italiano, Joseph E ^a,b,f   Hartwig, John H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Platelet BioGenesis   (United States)

^c HARVARD UNIVERSITY   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e KAROLINSKA INSTITUTE   (Sweden)

^f BOSTON CHILDREN S HOSPITAL   (United States)

^g VILNIUS UNIVERSITY   (Lithuania)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; BETA TUBULIN; CILIOBREVIN D; CYTOPLASMIC DYNEIN; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN; TUBULIN;

ANIMAL CELL; ARTICLE; BLEACHING; CONTROLLED STUDY; FLUORESCENCE; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; MEGAKARYOCYTE; MICROTUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPLATELET ELONGATION; QUANTITATIVE STUDY; SHEAR STRESS; THROMBOCYTHEMIA; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS; ANIMAL; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; CYTOPLASM; GENE EXPRESSION; GENETICS; INTERFERENCE MICROSCOPY; MECHANICAL STRESS; MECHANOTRANSDUCTION; METABOLISM; PRIMARY CELL CULTURE; THROMBOCYTE;

ANIMALS; BLOOD PLATELETS; CELL DIFFERENTIATION; CYTOPLASM; CYTOPLASMIC DYNEINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION; MECHANOTRANSDUCTION, CELLULAR; MEGAKARYOCYTES; MICE; MICROSCOPY, INTERFERENCE; MICROTUBULES; PRIMARY CELL CULTURE; RECOMBINANT PROTEINS; STRESS, MECHANICAL; THROMBOPOIESIS; TUBULIN;

EID: 84921823935     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-09-600858     Document Type: Article

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