Programming thermoresponsiveness of nanovelcro substrates enables effective purification of circulating tumor cells in lung cancer patients

ACS Nano

Volumn 9, Issue 1, 2015, Pages 62-70

  Ke, Zunfu ^a,b   Lin, Millicent ^a,b   Chen, Jie Fu ^b   Choi, Jin Sil ^b   Zhang, Yang ^b   Fong, Anna ^b   Liang, An Jou ^b   Chen, Shang Fu ^b   Li, Qingyu ^b   Fang, Wenfeng ^b   Zhang, Pingshan ^b   Garcia, Mitch A ^b   Lee, Tom ^b   Song, Min ^b   Lin, Hsing An ^c   Zhao, Haichao ^c   Luo, Shyh Chyang ^c,d   Hou, Shuang ^b   Yu, Hsiao Hua ^c,e   Tseng, Hsian Rong ^b  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RIKEN   (Japan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e INSTITUTE OF CHEMISTRY   (Taiwan)

Author keywords

cancer diagnosis; circulating tumor cells; nanostructured materials; non small cell lung cancer; thermoresponsive polymer

Indexed keywords

BIOLOGICAL ORGANS; BIOLOGY; BIOPSY; CELLS; CYTOLOGY; DISEASES; NANOSTRUCTURED MATERIALS; PHYSIOLOGICAL MODELS; PURIFICATION; SURFACE CHEMISTRY; TEMPERATURE CONTROL; TUMORS;

CANCER DIAGNOSIS; CIRCULATING TUMOR CELLS; NON SMALL CELL LUNG CANCER; OPERATIONAL PARAMETERS; PROGNOSTIC SIGNIFICANCE; THERAPEUTIC INTERVENTION; THERMO RESPONSIVENESS; THERMORESPONSIVE POLYMER;

DIAGNOSIS;

ANTIBODY; CELL ADHESION MOLECULE; NANOMATERIAL; TUMOR ANTIGEN; TUMOR-ASSOCIATED ANTIGEN GA733;

ADULT; AGED; CELL SEPARATION; CHEMISTRY; FEMALE; HUMAN; IMMUNOLOGY; LUNG TUMOR; MALE; MIDDLE AGED; NANOTECHNOLOGY; NON SMALL CELL LUNG CANCER; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROCEDURES; TEMPERATURE; TUMOR CELL LINE; TUMOR EMBOLISM;

ADULT; AGED; ANTIBODIES; ANTIGENS, NEOPLASM; BASE SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL SEPARATION; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NANOSTRUCTURES; NANOTECHNOLOGY; NEOPLASTIC CELLS, CIRCULATING; TEMPERATURE;

EID: 84921819921     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn5056282     Document Type: Article

References (40)

1. Pantel, K.; Alix-Panabieres, C. Circulating Tumour Cells in Cancer Patients: Challenges and Perspectives Trends Mol. Med. 2010, 16, 398-406
2. Speicher, M. R.; Pantel, K. Tumor Signatures in the Blood Nat. Biotechnol. 2014, 32, 441-443
3. Cristofanilli, M.; Budd, G. T.; Ellis, M. J.; Stopeck, A.; Matera, J.; Miller, M. C.; Reuben, J. M.; Doyle, G. V.; Allard, W. J.; Terstappen, L. W. et al. Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer N. Engl. J. Med. 2004, 351, 781-791
4. Riethdorf, S.; Fritsche, H.; Muller, V.; Rau, T.; Schindlbeck, C.; Rack, B.; Janni, W.; Coith, C.; Beck, K.; Janicke, F. et al. Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: A Validation Study of the Cellsearch System Clin. Cancer Res. 2007, 13, 920-928
5. Shaffer, D. R.; Leversha, M. A.; Danila, D. C.; Lin, O.; Gonzalez-Espinoza, R.; Gu, B.; Anand, A.; Smith, K.; Maslak, P.; Doyle, G. V. et al. Circulating Tumor Cell Analysis in Patients with Progressive Castration-Resistant Prostate Cancer Clin. Cancer Res. 2007, 13, 2023-2029
6. Maheswaran, S.; Sequist, L. V.; Nagrath, S.; Ulkus, L.; Brannigan, B.; Collura, C. V.; Inserra, E.; Diederichs, S.; Iafrate, A. J.; Bell, D. W. et al. Detection of Mutations in EGFR in Circulating Lung-Cancer Cells N. Engl. J. Med. 2008, 359, 366-377
7. Ni, X.; Zhuo, M.; Su, Z.; Duan, J.; Gao, Y.; Wang, Z.; Zong, C.; Bai, H.; Chapman, A. R.; Zhao, J. et al. Reproducible Copy Number Variation Patterns among Single Circulating Tumor Cells of Lung Cancer Patients Proc. Natl. Acad. Sci. U.S.A. 2013, 110, 21083-21088
8. Bidard, F. C.; Weigelt, B.; Reis-Filho, J. S. Going with the Flow: From Circulating Tumor Cells to DNA Sci. Transl. Med. 2013, 5, 207ps214
9. Lohr, J. G.; Adalsteinsson, V. A.; Cibulskis, K.; Choudhury, A. D.; Rosenberg, M.; Cruz-Gordillo, P.; Francis, J. M.; Zhang, C. Z.; Shalek, A. K.; Satija, R. et al. Whole-Exome Sequencing of Circulating Tumor Cells Provides a Window into Metastatic Prostate Cancer Nat. Biotechnol. 2014, 32, 479-484
10. Zhang, L.; Ridgway, L. D.; Wetzel, M. D.; Ngo, J.; Yin, W.; Kumar, D.; Goodman, J. C.; Groves, M. D.; Marchetti, D. The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis Sci. Transl. Med. 2013, 5, 180ra148
11. Yu, M.; Bardia, A.; Aceto, N.; Bersani, F.; Madden, M. W.; Donaldson, M. C.; Desai, R.; Zhu, H.; Comaills, V.; Zheng, Z. et al. Cancer Therapy. Ex Vivo Culture of Circulating Breast Tumor Cells for Individualized Testing of Drug Susceptibility Science 2014, 345, 216-220
12. Wang, S.; Wang, H.; Jiao, J.; Chen, K. J.; Owens, G. E.; Kamei, K.; Sun, J.; Sherman, D. J.; Behrenbruch, C. P.; Wu, H. et al. Three-Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor Cells Angew. Chem., Int. Ed. 2009, 48, 8970-8973
13. 2 Nanofiber-Based Cell Capture Assay for Detecting Circulating Tumor Cells from Colorectal and Gastric Cancer Patients Adv. Mater. 2012, 24, 2756-2760
14. Sekine, J.; Luo, S. C.; Wang, S.; Zhu, B.; Tseng, H. R.; Yu, H. H. Functionalized Conducting Polymer Nanodots for Enhanced Cell Capturing: The Synergistic Effect of Capture Agents and Nanostructures Adv. Mater. 2011, 23, 4788-4792
15. Hsiao, Y.-S.; Luo, S.-C.; Hou, S.; Zhu, B.; Sekine, J.; Kuo, C.-W.; Chueh, D.-Y.; Yu, H.-h.; Tseng, H.-R.; Chen, P. 3D Bioelectronic Interface: Capturing Circulating Tumor Cells onto Conducting Polymer-Based Micro/Nanorod Arrays with Chemical and Topographical Control Small 2014, 10, 3012-3017
16. Lin, M.; Chen, J. F.; Lu, Y. T.; Zhang, Y.; Song, J.; Hou, S.; Ke, Z.; Tseng, H. R. Nanostructure Embedded Microchips for Detection, Isolation, and Characterization of Circulating Tumor Cells Acc. Chem. Res. 2014, 10, 2941-2950
17. Lee, H.; Jang, Y.; Seo, J.; Nam, J.-M.; Char, K. Nanoparticle-Functionalized Polymer Platform for Controlling Metastatic Cancer Cell Adhesion, Shape, and Motility ACS Nano 2011, 5, 5444-5456
18. Park, G.-S.; Kwon, H.; Kwak, D. W.; Park, S. Y.; Kim, M.; Lee, J.-H.; Han, H.; Heo, S.; Li, X. S.; Lee, J. H. et al. Full Surface Embedding of Gold Clusters on Silicon Nanowires for Efficient Capture and Photothermal Therapy of Circulating Tumor Cells Nano Lett. 2012, 12, 1638-1642
19. Banerjee, S. S.; Paul, D.; Bhansali, S. G.; Aher, N. D.; Jalota-Badhwar, A.; Khandare, J. Enhancing Surface Interactions with Colon Cancer Cells on a Transferrin-Conjugated 3D Nanostructured Substrate Small 2012, 8, 1657-1663
20. Liu, X.; Chen, L.; Liu, H.; Yang, G.; Zhang, P.; Han, D.; Wang, S.; Jiang, L. Bio-Inspired Soft Polystyrene Nanotube Substrate for Rapid and Highly Efficient Breast Cancer-Cell Capture NPG Asia Mater. 2013, 5, e63
21. 2 Nanoparticle-Based Cell Immunoassay for Circulating Tumor Cells Capture and Identification from Cancer Patients Biomed. Microdevices 2013, 15, 617-626
22. Zhang, P.; Chen, L.; Xu, T.; Liu, H.; Liu, X.; Meng, J.; Yang, G.; Jiang, L.; Wang, S. Programmable Fractal Nanostructured Interfaces for Specific Recognition and Electrochemical Release of Cancer Cells Adv. Mater. 2013, 25, 3566-3570
23. Yoon, H. J.; Kim, T. H.; Zhang, Z.; Azizi, E.; Pham, T. M.; Paoletti, C.; Lin, J.; Ramnath, N.; Wicha, M. S.; Hayes, D. F. et al. Sensitive Capture of Circulating Tumour Cells by Functionalized Graphene Oxide Nanosheets Nat. Nanotechnol. 2013, 8, 735-741
24. Wang, S.; Liu, K.; Liu, J.; Yu, Z. T.; Xu, X.; Zhao, L.; Lee, T.; Lee, E. K.; Reiss, J.; Lee, Y. K. et al. Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers Angew. Chem., Int. Ed. 2011, 50, 3084-3088
25. Lu, Y. T.; Zhao, L.; Shen, Q.; Garcia, M. A.; Wu, D.; Hou, S.; Song, M.; Xu, X.; Ouyang, W. H.; Ouyang, W. W. et al. Nanovelcro Chip for Ctc Enumeration in Prostate Cancer Patients Methods 2013, 64, 144-152
26. Stroock, A. D.; Dertinger, S. K.; Ajdari, A.; Mezic, I.; Stone, H. A.; Whitesides, G. M. Chaotic Mixer for Microchannels Science 2002, 295, 647-651
27. Hou, S.; Zhao, L.; Shen, Q.; Yu, J.; Ng, C.; Kong, X.; Wu, D.; Song, M.; Shi, X.; Xu, X. et al. Polymer Nanofiber-Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells Angew. Chem., Int. Ed. 2013, 52, 3379-3383
28. Zhao, L.; Lu, Y. T.; Li, F.; Wu, K.; Hou, S.; Yu, J.; Shen, Q.; Wu, D.; Song, M.; Ouyang, W. H. et al. High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing Adv. Mater. 2013, 25, 2897-2902
29. Hou, S.; Zhao, H.; Zhao, L.; Shen, Q.; Wei, K. S.; Suh, D. Y.; Nakao, A.; Garcia, M. A.; Song, M.; Lee, T. et al. Capture and Stimulated Release of Circulating Tumor Cells on Polymer-Grafted Silicon Nanostructures Adv. Mater. 2013, 25, 1547-1551
30. Okano, T.; Yamada, N.; Okuhara, M.; Sakai, H.; Sakurai, Y. Mechanism of Cell Detachment from Temperature-Modulated, Hydrophilic-Hydrophobic Polymer Surfaces Biomaterials 1995, 16, 297-303
31. Sheng, W.; Ogunwobi, O. O.; Chen, T.; Zhang, J.; George, T. J.; Liu, C.; Fan, Z. H. Capture, Release and Culture of Circulating Tumor Cells from Pancreatic Cancer Patients Using an Enhanced Mixing Chip Lab Chip 2014, 14, 89-98
32. Kamangar, F.; Dores, G. M.; Anderson, W. F. Patterns of Cancer Incidence, Mortality, and Prevalence across Five Continents: Defining Priorities To Reduce Cancer Disparities in Different Geographic Regions of the World J. Clin. Oncol. 2006, 24, 2137-2150
33. Jemal, A.; Siegel, R.; Ward, E.; Hao, Y.; Xu, J.; Thun, M. J. Cancer Statistics, 2009 CA Cancer J. Clin. 2009, 59, 225-249
34. Pao, W.; Chmielecki, J. Rational, Biologically Based Treatment of EGFR-Mutant Non-Small-Cell Lung Cancer Nat. Rev. Cancer 2010, 10, 760-774
35. Hirsch, F. R.; Bunn, P. A., Jr. EGFR Testing in Lung Cancer Is Ready for Prime Time Lancet Oncol. 2009, 10, 432-433
36. Cross, D. A.; Ashton, S. E.; Ghiorghiu, S.; Eberlein, C.; Nebhan, C. A.; Spitzler, P. J.; Orme, J. P.; Finlay, M. R.; Ward, R. A.; Mellor, M. J. et al. Azd9291, an Irreversible EGFR TKI, Overcomes T790m-Mediated Resistance to EGFR Inhibitors in Lung Cancer Cancer Discovery 2014, 4, 1046-1061
37. Walter, A. O.; Sjin, R. T.; Haringsma, H. J.; Ohashi, K.; Sun, J.; Lee, K.; Dubrovskiy, A.; Labenski, M.; Zhu, Z.; Wang, Z. et al. Discovery of a Mutant-Selective Covalent Inhibitor of EGFR That Overcomes T790m-Mediated Resistance in NSCLC Cancer Discovery 2013, 3, 1404-1415
38. Wang, S.; Liu, K.; Liu, J.; Yu, Z. T.-F.; Xu, X.; Zhao, L.; Lee, T.; Lee, E. K.; Reiss, J.; Lee, Y.-K. et al. Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers Angew. Chem., Int. Ed. 2011, 50, 3084-3088
39. Xia, Y.; Whitesides, G. M. Soft Lithography Annu. Rev. Mater. Sci. 1998, 28, 153-184
40. Peng, K.-Q.; Yan, Y.-J.; Gao, S.-P.; Zhu, J. Synthesis of Large-Area Silicon Nanowire Arrays via Self-Assembling Nanoelectrochemistry Adv. Mater. 2002, 14, 1164-1167