The cancer glycocalyx mechanically primes integrin-mediated growth and survival

Nature

Volumn 511, Issue 7509, 2014, Pages 319-325

  Paszek, Matthew J ^a,b,c,d   Dufort, Christopher C ^a,b   Rossier, Olivier ^e   Bainer, Russell ^a,b   Mouw, Janna K ^a   Godula, Kamil ^b,f,k   Hudak, Jason E ^b   Lakins, Jonathon N ^a   Wijekoon, Amanda C ^a,b   Cassereau, Luke ^a,b   Rubashkin, Matthew G ^a,b   Magbanua, Mark J ^g,h   Thorn, Kurt S ^a   Davidson, Michael W ⁱ   Rugo, Hope S ^g,h   Park, John W ^g,h   Hammer, Daniel A ^j   Giannone, Grégory ^e   Bertozzi, Carolyn R ^b   Weaver, Valerie M ^a,b,g,h  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Cornell University   (United States)

^d Laboratory of Atomic and Solid State Physics and Sibley School of Mechanical and Aerospace Engineering   (United States)

^e UNIVERSITÉ DE BORDEAUX   (France)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ FLORIDA STATE UNIVERSITY   (United States)

^j UNIVERSITY OF PENNSYLVANIA   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GROWTH FACTOR; INTEGRIN; MUCIN 1; MYOSIN ADENOSINE TRIPHOSPHATASE;

CANCER; CELL ORGANELLE; COMPUTER SIMULATION; GENE EXPRESSION; GROWTH; MATRIX; PHENOTYPE; PROTEIN; SURVIVAL; TUMOR;

ARTICLE; BREAST CELL; BREAST METASTASIS; CANCER GROWTH; CANCER SURVIVAL; CELL ADHESION; CELL GROWTH; CELL SURVIVAL; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; CONFORMATIONAL TRANSITION; EXTRACELLULAR MATRIX; FLUORESCENCE RESONANCE ENERGY TRANSFER; FOCAL ADHESION; GLYCOCALYX; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE STRUCTURE; UPREGULATION;

ANIMALS; BREAST; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; FIBROBLASTS; GLYCOCALYX; GLYCOPROTEINS; HUMANS; IMMOBILIZED PROTEINS; INTEGRINS; MICE; MOLECULAR TARGETED THERAPY; MUCIN-1; NEOPLASM METASTASIS; NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; PROTEIN BINDING; RECEPTORS, CELL SURFACE;

EID: 84904436467     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13535     Document Type: Article

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