메뉴 건너뛰기




Volumn 134, Issue 6, 2014, Pages 1335-1345

A transplantable TH-MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma

Author keywords

anti GD2 mAb therapy; autologous mouse model; immunotherapy; neuroblastoma; NK cell

Indexed keywords

GANGLIOSIDE GD2; MONOCLONAL ANTIBODY;

EID: 84891835638     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28463     Document Type: Article
Times cited : (47)

References (47)
  • 2
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. New Engl J Med 1985; 313: 1111-6.
    • (1985) New Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3
  • 3
    • 61449106633 scopus 로고    scopus 로고
    • Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: A children's oncology group study
    • Matthay KK, Reynolds CP, Seeger RC, et al. Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group study. J Clin Oncol 2009; 27: 1007-13.
    • (2009) J Clin Oncol , vol.27 , pp. 1007-1013
    • Matthay, K.K.1    Reynolds, C.P.2    Seeger, R.C.3
  • 4
    • 77957341503 scopus 로고    scopus 로고
    • Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma
    • Yu AL, Gilman AL, Ozkaynak MF, et al. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. New Engl J Med 2010; 363: 1324-34.
    • (2010) New Engl J Med , vol.363 , pp. 1324-1334
    • Yu, A.L.1    Gilman, A.L.2    Ozkaynak, M.F.3
  • 5
    • 73149091818 scopus 로고    scopus 로고
    • KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma
    • Venstrom JM, Zheng J, Noor N, et al. KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma. Clin Cancer Res 2009; 15: 7330-4.
    • (2009) Clin Cancer Res , vol.15 , pp. 7330-7334
    • Venstrom, J.M.1    Zheng, J.2    Noor, N.3
  • 6
    • 78649968328 scopus 로고    scopus 로고
    • Genotypes of NK cell KIR receptors, their ligands, and Fcgamma receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy
    • Delgado DC, Hank JA, Kolesar J, et al. Genotypes of NK cell KIR receptors, their ligands, and Fcgamma receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy. Cancer Res 2010; 70: 9554-61.
    • (2010) Cancer Res , vol.70 , pp. 9554-9561
    • Delgado, D.C.1    Hank, J.A.2    Kolesar, J.3
  • 7
    • 84865960648 scopus 로고    scopus 로고
    • Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment
    • Tarek N, Le Luduec JB, Gallagher MM, et al. Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment. J Clin Invest 2012; 122: 3260-70.
    • (2012) J Clin Invest , vol.122 , pp. 3260-3270
    • Tarek, N.1    Le Luduec, J.B.2    Gallagher, M.M.3
  • 8
    • 13744257211 scopus 로고    scopus 로고
    • Expression of MHC class I, MHC class II, and cancer germline antigens in neuroblastoma
    • Wolfl M, Jungbluth AA, Garrido F, et al. Expression of MHC class I, MHC class II, and cancer germline antigens in neuroblastoma. Cancer Immunol Immunother 2005; 54: 400-6.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 400-406
    • Wolfl, M.1    Jungbluth, A.A.2    Garrido, F.3
  • 9
    • 22744453776 scopus 로고    scopus 로고
    • Multiple defects of the antigen-processing machinery components in human neuroblastoma: Immunotherapeutic implications
    • Raffaghello L, Prigione I, Bocca P, et al. Multiple defects of the antigen-processing machinery components in human neuroblastoma: immunotherapeutic implications. Oncogene 2005; 24: 4634-44.
    • (2005) Oncogene , vol.24 , pp. 4634-4644
    • Raffaghello, L.1    Prigione, I.2    Bocca, P.3
  • 11
    • 33845387727 scopus 로고    scopus 로고
    • Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR
    • Jacobs JF, Brasseur F, Hulsbergen-van de Kaa CA, et al. Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR. Int J Cancer 2007; 120: 67-74.
    • (2007) Int J Cancer , vol.120 , pp. 67-74
    • Jacobs, J.F.1    Brasseur, F.2    Hulsbergen-Van De Kaa, C.A.3
  • 12
    • 33749843270 scopus 로고    scopus 로고
    • Tumor mRNA-transfected dendritic cells stimulate the generation of CTL that recognize neuroblastoma-associated antigens and kill tumor cells: Immunotherapeutic implications
    • Morandi F, Chiesa S, Bocca P, et al. Tumor mRNA-transfected dendritic cells stimulate the generation of CTL that recognize neuroblastoma-associated antigens and kill tumor cells: immunotherapeutic implications. Neoplasia (New York, NY) 2006; 8: 833-42.
    • (2006) Neoplasia (New York, NY) , vol.8 , pp. 833-842
    • Morandi, F.1    Chiesa, S.2    Bocca, P.3
  • 13
    • 34247324316 scopus 로고    scopus 로고
    • Immunosurveillance and survivin-specific T-cell immunity in children with high-risk neuroblastoma
    • Coughlin CM, Fleming MD, Carroll RG, et al. Immunosurveillance and survivin-specific T-cell immunity in children with high-risk neuroblastoma. J Clin Oncol 2006; 24: 5725-34.
    • (2006) J Clin Oncol , vol.24 , pp. 5725-5734
    • Coughlin, C.M.1    Fleming, M.D.2    Carroll, R.G.3
  • 14
    • 78149465322 scopus 로고    scopus 로고
    • Immunomodulation with dendritic cells and donor lymphocyte infusion converge to induce graft vs neuroblastoma reactions without GVHD after allogeneic bone marrow transplantation
    • Ash S, Stein J, Askenasy N, et al. Immunomodulation with dendritic cells and donor lymphocyte infusion converge to induce graft vs neuroblastoma reactions without GVHD after allogeneic bone marrow transplantation. Br J Cancer 2010; 103: 1597-605.
    • (2010) Br J Cancer , vol.103 , pp. 1597-1605
    • Ash, S.1    Stein, J.2    Askenasy, N.3
  • 15
    • 79959507720 scopus 로고    scopus 로고
    • Depletion of CD25 T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma
    • Jing W, Yan X, Hallett WH, et al. Depletion of CD25 T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma. Blood 2011; 117: 6952-62.
    • (2011) Blood , vol.117 , pp. 6952-6962
    • Jing, W.1    Yan, X.2    Hallett, W.H.3
  • 16
    • 34247588130 scopus 로고    scopus 로고
    • CD25+ regulatory T cell inhibition enhances vaccine-induced immunity to neuroblastoma
    • Johnson BD, Jing W, Orentas RJ,. CD25+ regulatory T cell inhibition enhances vaccine-induced immunity to neuroblastoma. J Immunother 2007; 30: 203-14.
    • (2007) J Immunother , vol.30 , pp. 203-214
    • Johnson, B.D.1    Jing, W.2    Orentas, R.J.3
  • 17
    • 51049119661 scopus 로고    scopus 로고
    • A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity
    • Huebener N, Fest S, Strandsby A, et al. A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity. Mol Cancer Ther 2008; 7: 2241-51.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2241-2251
    • Huebener, N.1    Fest, S.2    Strandsby, A.3
  • 18
    • 0030999641 scopus 로고    scopus 로고
    • Targeted expression of MYCN causes neuroblastoma in transgenic mice
    • Weiss WA, Aldape K, Mohapatra G, et al. Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J 1997; 16: 2985-95.
    • (1997) EMBO J , vol.16 , pp. 2985-2995
    • Weiss, W.A.1    Aldape, K.2    Mohapatra, G.3
  • 19
    • 68449084682 scopus 로고    scopus 로고
    • MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development
    • Alam G, Cui H, Shi H, et al. MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. Am J Pathol 2009; 175: 856-66.
    • (2009) Am J Pathol , vol.175 , pp. 856-866
    • Alam, G.1    Cui, H.2    Shi, H.3
  • 20
    • 53649092954 scopus 로고    scopus 로고
    • Histological profile of tumours from MYCN transgenic mice
    • Moore HC, Wood KM, Jackson MS, et al. Histological profile of tumours from MYCN transgenic mice. J Clin Pathol 2008; 61: 1098-103.
    • (2008) J Clin Pathol , vol.61 , pp. 1098-1103
    • Moore, H.C.1    Wood, K.M.2    Jackson, M.S.3
  • 21
    • 0141816855 scopus 로고    scopus 로고
    • Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors
    • Hackett CS, Hodgson JG, Law ME, et al. Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Res 2003; 63: 5266-73.
    • (2003) Cancer Res , vol.63 , pp. 5266-5273
    • Hackett, C.S.1    Hodgson, J.G.2    Law, M.E.3
  • 22
    • 82555170563 scopus 로고    scopus 로고
    • MiRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs
    • Terrile M, Bryan K, Vaughan L, et al. miRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs. PloS One 2011; 6: e28356.
    • (2011) PloS One , vol.6
    • Terrile, M.1    Bryan, K.2    Vaughan, L.3
  • 23
    • 70249151443 scopus 로고    scopus 로고
    • A simple PCR method for rapid genotype analysis of the TH-MYCN transgenic mouse
    • Haraguchi S, Nakagawara A,. A simple PCR method for rapid genotype analysis of the TH-MYCN transgenic mouse. PloS One 2009; 4: e6902.
    • (2009) PloS One , vol.4
    • Haraguchi, S.1    Nakagawara, A.2
  • 24
    • 61449200632 scopus 로고    scopus 로고
    • Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells
    • Acosta S, Lavarino C, Paris R, et al. Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells. BMC Dev Biol 2009; 9: 12.
    • (2009) BMC Dev Biol , vol.9 , pp. 12
    • Acosta, S.1    Lavarino, C.2    Paris, R.3
  • 25
    • 0141617477 scopus 로고    scopus 로고
    • Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma
    • Burkhart CA, Cheng AJ, Madafiglio J, et al. Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma. J Natl Cancer Inst 2003; 95: 1394-403.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1394-1403
    • Burkhart, C.A.1    Cheng, A.J.2    Madafiglio, J.3
  • 26
    • 33745528911 scopus 로고    scopus 로고
    • FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor
    • Cheung NK, Sowers R, Vickers AJ, et al. FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor. J Clin Oncol 2006; 24: 2885-90.
    • (2006) J Clin Oncol , vol.24 , pp. 2885-2890
    • Cheung, N.K.1    Sowers, R.2    Vickers, A.J.3
  • 27
    • 79960967930 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions contribute to functional T-cell impairment in patients who relapse with cancer after allogeneic stem cell transplantation
    • Norde WJ, Maas F, Hobo W, et al. PD-1/PD-L1 interactions contribute to functional T-cell impairment in patients who relapse with cancer after allogeneic stem cell transplantation. Cancer Res 2011; 71: 5111-22.
    • (2011) Cancer Res , vol.71 , pp. 5111-5122
    • Norde, W.J.1    Maas, F.2    Hobo, W.3
  • 28
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Nagaraj S, Collazo M, et al. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 2008; 181: 5791-802.
    • (2008) J Immunol , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3
  • 29
    • 79955717564 scopus 로고    scopus 로고
    • Preclinical models for neuroblastoma: Establishing a baseline for treatment
    • Teitz T, Stanke JJ, Federico S, et al. Preclinical models for neuroblastoma: establishing a baseline for treatment. PloS One 2011; 6: e19133.
    • (2011) PloS One , vol.6
    • Teitz, T.1    Stanke, J.J.2    Federico, S.3
  • 30
    • 84863753157 scopus 로고    scopus 로고
    • The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma
    • Berry T, Luther W, Bhatnagar N, et al. The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma. Cancer Cell 2012; 22: 117-30.
    • (2012) Cancer Cell , vol.22 , pp. 117-130
    • Berry, T.1    Luther, W.2    Bhatnagar, N.3
  • 31
    • 34250025899 scopus 로고    scopus 로고
    • Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma
    • Cheng AJ, Cheng NC, Ford J, et al. Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma. Eur J Cancer 2007; 43: 1467-75.
    • (2007) Eur J Cancer , vol.43 , pp. 1467-1475
    • Cheng, A.J.1    Cheng, N.C.2    Ford, J.3
  • 32
    • 84861070743 scopus 로고    scopus 로고
    • High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: New tools for pediatric drug discovery
    • Stauffer JK, Orentas RJ, Lincoln E, et al. High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery. Cancer Invest 2012; 30: 343-63.
    • (2012) Cancer Invest , vol.30 , pp. 343-363
    • Stauffer, J.K.1    Orentas, R.J.2    Lincoln, E.3
  • 33
    • 4344606588 scopus 로고    scopus 로고
    • Mechanisms of embryonal tumor initiation: Distinct roles for MycN expression and MYCN amplification
    • Hansford LM, Thomas WD, Keating JM, et al. Mechanisms of embryonal tumor initiation: distinct roles for MycN expression and MYCN amplification. Proc Natl Acad Sci USA 2004; 101: 12664-9.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 12664-12669
    • Hansford, L.M.1    Thomas, W.D.2    Keating, J.M.3
  • 34
    • 77957764089 scopus 로고    scopus 로고
    • MiR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma
    • Swarbrick A, Woods SL, Shaw A, et al. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nat Med 2011; 16: 1134-40.
    • (2011) Nat Med , vol.16 , pp. 1134-1140
    • Swarbrick, A.1    Woods, S.L.2    Shaw, A.3
  • 35
    • 36749069011 scopus 로고    scopus 로고
    • Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis
    • Liu T, Tee AE, Porro A, et al. Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis. Proc Natl Acad Sci USA 2007; 104: 18682-7.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 18682-18687
    • Liu, T.1    Tee, A.E.2    Porro, A.3
  • 36
    • 23944504734 scopus 로고    scopus 로고
    • Mechanisms of immune evasion of human neuroblastoma
    • Raffaghello L, Prigione I, Airoldi I, et al. Mechanisms of immune evasion of human neuroblastoma. Cancer Lett 2005; 228: 155-61.
    • (2005) Cancer Lett , vol.228 , pp. 155-161
    • Raffaghello, L.1    Prigione, I.2    Airoldi, I.3
  • 37
    • 0037779101 scopus 로고    scopus 로고
    • Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+ neuroblastoma cells undergo apoptosis following interaction with CD40L
    • Airoldi I, Lualdi S, Bruno S, et al. Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+ neuroblastoma cells undergo apoptosis following interaction with CD40L. Br J Cancer 2003; 88: 1527-36.
    • (2003) Br J Cancer , vol.88 , pp. 1527-1536
    • Airoldi, I.1    Lualdi, S.2    Bruno, S.3
  • 38
    • 0035076824 scopus 로고    scopus 로고
    • Lack of HLA-class i antigens in human neuroblastoma cells: Analysis of its relationship to TAP and tapasin expression
    • Corrias MV, Occhino M, Croce M, et al. Lack of HLA-class I antigens in human neuroblastoma cells: analysis of its relationship to TAP and tapasin expression. Tissue Antigens 2001; 57: 110-7.
    • (2001) Tissue Antigens , vol.57 , pp. 110-117
    • Corrias, M.V.1    Occhino, M.2    Croce, M.3
  • 39
    • 79951886003 scopus 로고    scopus 로고
    • Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: A Children's Oncology Group (COG) phase II study
    • Shusterman S, London WB, Gillies SD, et al. Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study. J Clin Oncol 2010; 28: 4969-75.
    • (2010) J Clin Oncol , vol.28 , pp. 4969-4975
    • Shusterman, S.1    London, W.B.2    Gillies, S.D.3
  • 40
    • 0036786290 scopus 로고    scopus 로고
    • Dendritic cells for NK/LAK activation: Rationale for multicellular immunotherapy in neuroblastoma patients
    • Valteau-Couanet D, Leboulaire C, Maincent K, et al. Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients. Blood 2002; 100: 2554-61.
    • (2002) Blood , vol.100 , pp. 2554-2561
    • Valteau-Couanet, D.1    Leboulaire, C.2    Maincent, K.3
  • 41
    • 6944241315 scopus 로고    scopus 로고
    • Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma
    • Raffaghello L, Prigione I, Airoldi I, et al. Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma. Neoplasia (New York, NY) 2004; 6: 558-68.
    • (2004) Neoplasia (New York, NY) , vol.6 , pp. 558-568
    • Raffaghello, L.1    Prigione, I.2    Airoldi, I.3
  • 42
    • 84867052186 scopus 로고    scopus 로고
    • Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
    • Asgharzadeh S, Salo JA, Ji L, et al. Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma. J Clin Oncol 2012; 30: 3525-32.
    • (2012) J Clin Oncol , vol.30 , pp. 3525-3532
    • Asgharzadeh, S.1    Salo, J.A.2    Ji, L.3
  • 43
    • 77954753261 scopus 로고    scopus 로고
    • Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors
    • van Dongen M, Savage ND, Jordanova ES, et al. Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors. Int J Cancer 2010; 127: 899-909.
    • (2010) Int J Cancer , vol.127 , pp. 899-909
    • Van Dongen, M.1    Savage, N.D.2    Jordanova, E.S.3
  • 44
    • 80053421470 scopus 로고    scopus 로고
    • Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice
    • Lu T, Ramakrishnan R, Altiok S, et al. Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. J Clin Invest 2011; 121: 4015-29.
    • (2011) J Clin Invest , vol.121 , pp. 4015-4029
    • Lu, T.1    Ramakrishnan, R.2    Altiok, S.3
  • 45
    • 0031717502 scopus 로고    scopus 로고
    • Disialoganglioside G(D2) loss following monoclonal antibody therapy is rare in neuroblastoma
    • Kramer K, Gerald WL, Kushner BH, et al. Disialoganglioside G(D2) loss following monoclonal antibody therapy is rare in neuroblastoma. Clin Cancer Res 1998; 4: 2135-9.
    • (1998) Clin Cancer Res , vol.4 , pp. 2135-2139
    • Kramer, K.1    Gerald, W.L.2    Kushner, B.H.3
  • 46
    • 3543119461 scopus 로고    scopus 로고
    • Immune cell-mediated antitumor activities of GD2-targeted liposomal c-myb antisense oligonucleotides containing CpG motifs
    • Brignole C, Pastorino F, Marimpietri D, et al. Immune cell-mediated antitumor activities of GD2-targeted liposomal c-myb antisense oligonucleotides containing CpG motifs. J Natl Cancer Inst 2004; 96: 1171-80.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1171-1180
    • Brignole, C.1    Pastorino, F.2    Marimpietri, D.3
  • 47
    • 0030690067 scopus 로고    scopus 로고
    • Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow
    • Lode HN, Xiang R, Varki NM, et al. Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow. J Natl Cancer Inst 1997; 89: 1586-94.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1586-1594
    • Lode, H.N.1    Xiang, R.2    Varki, N.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.