Design and characterization of an economical 192Ir hemi-brain small animal irradiator

International Journal of Radiation Biology

Volumn 90, Issue 10, 2014, Pages 936-942

  Grams, Michael P ^a   Wilson, Zachary C ^a   Sio, Terence T ^a   Beltran, Chris J ^a   Tryggestad, Erik J ^a   Gupta, Shiv K ^a   Blackwell, Charles R ^a   McCollough, Kevin P ^a   Sarkaria, Jann N ^a   Furutani, Keith M ^a  

^a MAYO CLINIC   (United States)

Author keywords

hemi brain; Iridium 192 HDR; Small animal irradiator

Indexed keywords

IRIDIUM 192; TUNGSTEN; IRIDIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRACHYTHERAPY; COLLIMATOR; DOSIMETRY; ELECTRON BEAM; FILM DOSIMETER; HEMI BRAIN SMALL ANIMAL IRRADIATOR; LINEAR ACCELERATOR; MONTE CARLO METHOD; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON RADIATION; RADIOTHERAPY UNIT; ANIMAL; BRAIN; COMPUTER AIDED DESIGN; COST BENEFIT ANALYSIS; DEVICE FAILURE ANALYSIS; DEVICES; ECONOMICS; ELECTRONICS; EQUIPMENT DESIGN; RADIATION DOSE; RADIATION RESPONSE; RADIOMETRY; VETERINARY; WHOLE BODY RADIATION;

ANIMALIA; MUS;

ANIMALS; BRACHYTHERAPY; BRAIN; COMPUTER-AIDED DESIGN; COST-BENEFIT ANALYSIS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; IRIDIUM RADIOISOTOPES; MICE; MINIATURIZATION; RADIATION DOSAGE; RADIOMETRY; WHOLE-BODY IRRADIATION;

EID: 84921812343     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2014.922719     Document Type: Article

References (14)

1. Agostinelli S, Allison J, Amako K, Apostolakis J, Araujo H, Arce P, Asai M, Axen D, Banerjee S, et al. 2003. GEANT4-a simulation toolkit. Nuc Instrum Meth Phys Res A: Accelerat Spectrom Detect Assoc Equip 506:250-303.
2. Arndt CD, Wang IZ, Saito NG, Podgorsak MB. 2011. Dosimetric calibration and characterization for experimental mouse thoracic irradiation using orthovoltage X rays. Radiat Res 175:784-789.
3. Hill R, Kuncic Z, Baldock C. 2010. The water equivalence of solid phantoms for low energy photon beams. Medical Phys 37:4355.
4. Kiehl EL, Stojadinovic S, Malinowski KT, Limbrick D, Jost SC, Garbow JR, Rubin JB, Deasy JO, Khullar D, Izaguirre EW, Parikh PJ, Low DA, Hope AJ. 2008. Feasibility of small animal cranial irradiation with the microRT system. Med Phys 35:4735.
5. Lewis D, Micke A, Yu X, Chan MF. 2012. An efficient protocol for radiochromic film dosimetry combining calibration and measurement in a single scan. Med Phys 39:6339-6350.
6. Lye JE, Butler DJ, Webb DV. 2010. Enhanced epidermal dose caused by localized electron contamination from lead cutouts used in kilovoltage radiotherapy. Med Phys 37:3935.
7. Massillon-JL G. 2012. Energy dependence of the new Gafchromic EBT3 film:dose response curves for 50 KV, 6 and 15 MV X-ray beams. Int J Med Phys, Clin Engineer Radiat Oncol 1:60-65.
8. Niroomand-Rad A, Blackwell CR, Coursey BM, Gall KP, Galvin JM, McLaughlin WL, Meigooni AS, Nath R, Rodgers JE, Soares CG. 1998. Radiochromic film dosimetry: Recommendations of AAPM Radiation Therapy Committee Task Group 55. Med Phys 25: 2093-2115.
9. Palmer AL, Di Pietro P, Alobaidli S, Issa F, Doran S, Bradley D, Nisbet A. 2013. Comparison of methods for the measurement of radiation dose distributions in high dose rate (HDR) brachytherapy: Ge-doped optical fiber, EBT3 Gafchromic film, and PRESAGE(R) radiochromic plastic. Med Phys 40:061707.
10. Perl J, Shin J, Schumann J, Faddegon B, Paganetti H. 2012. TOPAS: An innovative proton Monte Carlo platform for research and clinical applications. Med Phys 39:6818-6837.
11. Podgorsak MB. 1990. Surface dose in intracavitary orthovoltage radiotherapy. Med Phys 17:635.
12. Stojadinovic S, Low DA, Hope AJ, Vicic M, Deasy JO, Cui J, Khullar D, Parikh PJ, Malinowski KT, Izaguirre EW, Mutic S, Grigsby PW. 2007. MicroRT - Small animal conformal irradiator. Med Phys 34:4706.
13. Verhaegen F, Granton P, Tryggestad E. 2011. Small animal radiotherapy research platforms. Phys Med Biol 56:R55-83.
14. Wong J, Armour E, Kazanzides P, Iordachita I, Tryggestad E, Deng H, Matinfar M, Kennedy C, Liu Z, Chan T, Gray O, Verhaegen F, McNutt T, Ford E, Deweese TL. 2008. High- resolution, small animal radiation research platform with X-ray tomographic guidance capabilities. Int J Radiat Oncol, Biol, Phys 71:1591-1599.