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Volumn 125, Issue 5, 2015, Pages 750-751

PI3Kβ inhibition: All that glitters is not gold

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GLYCOGEN SYNTHASE KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE BETA; PROTEIN KINASE B; UNCLASSIFIED DRUG; 1-PHOSPHATIDYLINOSITOL 3-KINASE P110 SUBUNIT, MOUSE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE;

EID: 84921802687     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-12-612564     Document Type: Note
Times cited : (8)

References (10)
  • 2
    • 21044454703 scopus 로고    scopus 로고
    • PI 3-kinase p110β: A new target for antithrombotic therapy
    • Jackson SP, Schoenwaelder SM, Goncalves I, et al. PI 3-kinase p110β: a new target for antithrombotic therapy. Nat Med. 2005;11(5):507-514.
    • (2005) Nat Med , vol.11 , Issue.5 , pp. 507-514
    • Jackson, S.P.1    Schoenwaelder, S.M.2    Goncalves, I.3
  • 3
    • 84866876711 scopus 로고    scopus 로고
    • Human target validation of phosphoinositide 3-kinase (PI3K)β: Effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor
    • Nylander S, Kull B, Björkman JA, et al. Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor. J Thromb Haemost. 2012;10(10):2127-2136.
    • (2012) J Thromb Haemost , vol.10 , Issue.10 , pp. 2127-2136
    • Nylander, S.1    Kull, B.2    Björkman, J.A.3
  • 5
    • 84896060546 scopus 로고    scopus 로고
    • Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling
    • Consonni A, Cipolla L, Guidetti G, et al. Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. Blood. 2012;119(3):847-856.
    • (2012) Blood , vol.119 , Issue.3 , pp. 847-856
    • Consonni, A.1    Cipolla, L.2    Guidetti, G.3
  • 6
    • 70349251723 scopus 로고    scopus 로고
    • Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets
    • Canobbio I, Stefanini L, Cipolla L, et al. Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets. Blood. 2009;114(10):2193-2196.
    • (2009) Blood , vol.114 , Issue.10 , pp. 2193-2196
    • Canobbio, I.1    Stefanini, L.2    Cipolla, L.3
  • 7
    • 77950423041 scopus 로고    scopus 로고
    • Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
    • Martin V, Guillermet-Guibert J, Chicanne G, et al. Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo. Blood. 2010;115(10):2008-2013.
    • (2010) Blood , vol.115 , Issue.10 , pp. 2008-2013
    • Martin, V.1    Guillermet-Guibert, J.2    Chicanne, G.3
  • 8
    • 84873547290 scopus 로고    scopus 로고
    • The prolinerich tyrosine kinase Pyk2 regulates platelet integrin aIIbβ3 outside-in signaling
    • Cipolla L, Consonni A, Guidetti G, et al. The prolinerich tyrosine kinase Pyk2 regulates platelet integrin aIIbβ3 outside-in signaling. J Thromb Haemost. 2013;11(2):345-356.
    • (2013) J Thromb Haemost , vol.11 , Issue.2 , pp. 345-356
    • Cipolla, L.1    Consonni, A.2    Guidetti, G.3
  • 10
    • 43549100273 scopus 로고    scopus 로고
    • GSK3β is a negative regulator of platelet function and thrombosis
    • Li D, August S, Woulfe DS. GSK3β is a negative regulator of platelet function and thrombosis. Blood. 2008;111(7):3522-3530.
    • (2008) Blood , vol.111 , Issue.7 , pp. 3522-3530
    • Li, D.1    August, S.2    Woulfe, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.