Pesticides, Gene Polymorphisms, and Bladder Cancer among Egyptian Agricultural Workers

Archives of Environmental and Occupational Health

Volumn 70, Issue 1, 2015, Pages 19-26

  Amr, Sania ^a   Dawson, Rebecca ^a   Saleh, Doaa A ^b   Magder, Laurence S ^a   St George, Diane Marie ^a   El Daly, Mai ^c   Squibb, Katherine ^a   Mikhail, Nabiel N ^d   Abdel Hamid, Mohamed ^e   Khaled, Hussein ^b   Loffredo, Christopher A ^f  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b CAIRO UNIVERSITY   (Egypt)

^c MENOUFIA UNIVERSITY   (Egypt)

^d ASSIUT UNIVERSITY   (Egypt)

^e MINIA UNIVERSITY   (Egypt)

^f GEORGETOWN UNIVERSITY   (United States)

Author keywords

agricultural workers; bladder cancer; Egypt; epidemiology; gene polymorphism; pesticides

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; PESTICIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); NQO1 PROTEIN, HUMAN; SOD3 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

ADULT; AGED; AGRICULTURAL WORKER; ARTICLE; BLADDER CANCER; BLADDER CARCINOMA; CANCER RISK; CONTROLLED STUDY; DNA POLYMORPHISM; EGYPTIAN; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEN'S HEALTH; MIDDLE AGED; PRIORITY JOURNAL; AGRICULTURAL WORKERS' DISEASES; AGRICULTURE; CASE CONTROL STUDY; CHEMICALLY INDUCED; DOSE RESPONSE; EGYPT; GENETICS; ODDS RATIO; RISK FACTOR; SMOKING; SOCIOECONOMICS; STATISTICS AND NUMERICAL DATA; URINARY BLADDER NEOPLASMS;

ADULT; AGED; AGRICULTURAL WORKERS' DISEASES; AGRICULTURE; CASE-CONTROL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; EGYPT; GENOTYPE; HUMANS; MALE; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); ODDS RATIO; PESTICIDES; POLYMORPHISM, GENETIC; RISK FACTORS; SMOKING; SOCIOECONOMIC FACTORS; SUPEROXIDE DISMUTASE; URINARY BLADDER NEOPLASMS;

EID: 84921797466     PISSN: 19338244     EISSN: 21544700     Source Type: Journal    
DOI: 10.1080/19338244.2013.853646     Document Type: Article

References (52)

1. Kiriluk KJ., Prasad SM., Patel AR., Steinberg GD., Smith ND. Bladder cancer risk from occupational and environmental exposures. Urol Oncol. 2012; 30: 199-211.
2. Jankovi S., Radosavljevi V. Risk factors for bladder cancer. Tumori. 2007; 93: 4-12.
3. Siemiatycki J., Richardson L., Straif K., et al. Listing occupational carcinogens. Environ Health Perspect. 2004; 112: 1447-1459.
4. Talaska G. Aromatic amines and human urinary bladder cancer: exposure sources and epidemiology. J Environ Sci Health C. 2003; 21: 29-43.
5. Negri E., La Vecchia C. Epidemiology and prevention of bladder cancer. Eur J Cancer Prev. 2001; 10: 7-14.
6. Boffetta P., Jourenkova N., Gustavsson P. Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control. 1997; 8: 444-472.
7. Amr S., Dawson., Saleh DA., et al. Agricultural workers and urinary bladder cancer risk in Egypt. Arch Environ Occup Health. 2014; 69: 3-10.
8. Cassidy A., Wang W., Wu X., Lin J. Risk of urinary bladder cancer: a case-control analysis of industry and occupation. BMC Cancer. 2009; 9: 443-450.
9. Dryson E., t Mannetje A., Walls C., et al. Case-control study of high risk occupations for bladder cancer in New Zealand. Int J Cancer. 2008; 122: 1340-1346.
10. Settimi L., Comba P., Carrieri P., et al. Cancer risk among female agricultural workers: a multi-center case-control study. Am J Ind Med. 1999; 36: 135-141.
11. Acquavella J., Olsen G., Cole P., et al. Cancer among farmers: a meta-analysis. Ann Epidemiol. 1998; 8: 64-74.
12. Blair A., Freeman LB. Epidemiologic studies of cancer in agricultural populations: observations and future directions. J Agromedicine. 2009; 14: 125-131.
13. Alavanja MCR., Sandler DP., Lynch CF., et al. Cancer incidence in the Agricultural Health Study. Scand J Work Environ Health. 2005; 31 (Suppl): 39-45.
14. Alavanja MC., Ross MK., Bonner MR. Increased cancer burden among pesticide applicators and others due to pesticide exposure. CA Cancer J Clin. 2013; 63: 120-142
15. International Agency for Research on Cancer. Occupational Exposures in Insecticide Applications, and Some Pesticides. IARC Monographs on the Evaluation of Carcinogenic Risk to Humans. Vol. 70. Lyon, France: International Agency for Research on Cancer; 1991.
16. Boers D., Portengen L., Bas Bueno-de-Mesquita H., Heederik D., Vermeulen R. Cause-specific mortality of Dutch chlorophenoxy herbicide manufacturing workers. Occup Environ Med. 2010; 67: 24-31.
17. Koutros S., Lynch CF., Ma X., et al. Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health Study. Int. J. Cancer. 2009; 124: 1206-1212.
18. Rusiecki JA., De Roos A., Lee WJ., et al. Cancer incidence among pesticide applicators exposed to atrazine in the Agricultural Health Study. J Natl Cancer Inst. 2004; 96: 1375-1382.
19. Viel JF., Challier B. Bladder cancer among french farmers: does exposure to pesticides in vineyards play a part? Occup Environ Med. 1995; 52: 587-592.
20. Koutros S., Alavanja MCR., Lubin JH., et al. An update of cancer incidence in the agricultural health study. J Occup Environl Med. 2010; 52: 1098-1105.
21. Rusiecki JA., Patel R., Koutros S., et al. Cancer incidence among pesticide applicators exposed to permethrin in the agricultural health study. Environ Health Perspect. 2009; 117: 581-586.
22. Choi YJ., Seelbach MJ., Pu H. Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression. Environ Health Perspect. 2010; 118: 976-981.
23. Banerjee BD., Seth V., Ahmed RS. Pesticide induced oxidative stress: perspectives and trends. Rev Environ Health. 2001; 16: 1-40.
24. Koutros S., Andreotti G., Berndt SI., et al. Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer. Pharmacogenet Genomics. 2011; 21: 615-623.
25. Savic-Radojevic A., Djukic T., Simic T., et al. GSTM1-null and GSTA1-low activity genotypes are associated with enhanced oxidative damage in bladder cancer. Redox Rep. 2013; 18: 1-7.
26. Ding G., Liu F., Shen B., Feng C., Xu J., Ding Q. The association between polymorphisms in prooxidant or antioxidant enzymes (myeloperoxidase, SOD2, and CAT) and genes and prostate cancer risk in the Chinese population of Han nationality. Clin Genitourin Cancer. 2012; 10: 251-255.
27. Siegel D., Gustafson DL., Dehn DL., et al. NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger. Mol Pharmacol. 2004; 65: 1238-1247.
28. Joseph P., Jaiswal AK. NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase. Proc Natl Acad Sci USA. 1994; 91: 8413-8417.
29. Rosenblum JS., Gilula NB., Lerner RA. On signal sequence polymorphisms and diseases of distribution. Proc Natl Acad Sci USA. 1996; 93: 4471-4473.
30. Traver RD., Siegel D., Beall HD., et al. Characterization of a polymorphism in NAD(P)H:quinone oxidoreductase (DT-diaphorase). Br J Cancer. 1997; 75: 69-75.
31. Sutton A., Imbert A., Igoudjil A., et al. The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability. Pharmacogenet Genomics. 2005; 15: 311-319.
32. Guo ZJ., Feng CL. The NQO1 rs1800566 polymorphism and risk of bladder cancer: evidence from 6,169 subjects. Asian Pacific J Cancer Prev. 2012; 13: 6343-6348.
33. Wang YH., Lee YH., Tseng PT., Shen CH., Chiou HY. Human NAD(P)H:quinone oxidoreductase 1 (NQO1) and sulfotransferase1A1 (SULT1A1) polymorphisms and urothelial cancer risk in Taiwan. J Cancer Res Clin Oncol. 2008; 134: 203-209.
34. Cengiz M., Ozaydin A., Ozkilic AC., Dedekarginoglu G. The investigation of GSTT1, GSTM1 and SOD polymorphism in bladder cancer patients. Int Urol Nephrol. 2007; 39: 1043-1048.
35. Chao C., Zhang Z-F., Berthiller J., Boffetta P., Hashibe M. NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2006; 15: 979-987.
36. Terry PD., Umbach DM., Taylor JA. No association between SOD2 or NQO1 genotypes and risk of bladder cancer. Cancer Epidemiol Biomarkers Prev. 2005; 14: 753-754.
37. Moore LE., Wiencke JK., Bates MN., Zheng S., Rey OA., Smith AH. Investigation of genetic polymorphismsand smoking in a bladder cancer case-control study in Argentina. Cancer Lett. 2004; 211: 199-207.
38. Hung RJ., Boffetta P., Brennan P., et al. Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk. Carcinogenesis. 2004; 25: 973-978.
39. Xu LL., Wain JC., Miller DP., et al. The NAD(P)H:quinone oxidoreductase 1 gene polymorphism and lung cancer: differential susceptibility based on smoking behavior. Cancer Epidemiol Biomarkers Prev. 2001; 10: 303-309.
40. Peluso M., Airoldi L., Magagnotti C., et al. White blood cell DNA adducts and fruit and vegetable consumption in bladder cancer. Carcinogenesis. 2000; 21: 183-187.
41. Schulz WA., Krummeck A., Rosinger I., et al. Increased frequency of a null-allele for NAD(P)H:quinone oxidoreductase in patients with urological malignancies. Pharmacogenetics. 1997; 7: 235-239.
42. Zheng YL., Amr S., Saleh DA., et al. Urinary bladder cancer risk factors in Egypt: a multicenter case-control study. Cancer Epidemiol Biomarkers Prev. 2012; 21: 537-546.
43. Goerlitz D., Amr S., Dash C., et al. Genetic polymorphisms in NQO1 and SOD2: interactions with smoking, schistosoma infection, and bladder cancer risk in Egypt. Urol Oncol. 2014; 32: 47e15-47e20.
44. Dich J., Zahm SH., Hanberg A., Adami HO. Pesticides and cancer. Cancer Causes Control. 1997; 8: 420-443.
45. Ezzat S., Abdel-Hamid M., Abdel-Latif ES., et al. Associations of pesticides, HCV, HBV, and hepatocellular carcinoma in Egypt. Int J Hyg Environ Health. 2005; 208: 329-339.
46. Kogevinas M., Becher H., Benn T., et al. Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins. An expanded and updated international cohort study. Am J Epidemiol. 1997; 145: 1061-1075.
47. Kang D., Lee KM., Park SK., et al. Functional variant of manganese superoxide dismutase (sod2 v16a) polymorphism is associated with prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Study. Cancer Epidemiol Biomarkers Prev. 2007; 16: 1581-1586.
48. Polytarchou C., Hatziapostolou M., Papadimitriou E. Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin regulatory peptide gene. J Biol Chem. 2005; 49: 40428-40435.
49. Wenk J., Brnneisen P., Wlaschek M., et al. Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J Biol Chem. 1999; 274: 25869-25876.
50. Wiencke JK., Pemble S., Ketterer B., et al. Gene deletion of glutathione S-transferase: Correlation with induced genetic damage and potential role in endogenous mutagenesis. Cancer Epidemiol Biomarkers Prev. 1995; 4: 253-259.
51. Kelsey KT., Spitz MR., Zuo ZF., et al. Polymorphisms in the glutathione S-transferase class and genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States). Cancer Causes Control. 1997; 8: 554-559.
52. Wolpert BJ., Amr S., Saleh DA., et al. Associations differ by sex for catechol-O-methyltransferase genotypes and bladder cancer risk in South Egypt. Urol Oncol. 2012; 30: 841-847.