Assessing the efficacy of candidate mosquito repellents against the background of an attractive source that mimics a human host

Medical and Veterinary Entomology

Volumn 28, Issue 4, 2014, Pages 407-413

  Menger, D J ^a   Van Loon, J J A ^a   Takken, W ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Aedes aegypti (Stegomyia aegypti); Anopheles gambiae; Behaviour; Bioassay; Repellent; Semiochemical

Indexed keywords

DIETHYLTOLUAMIDE; INSECT REPELLENT; LACTONE DERIVATIVE; LINALOOL; PARA MENTHANE 3,8 DIOL; UNCLASSIFIED DRUG;

BIOASSAY; CHEMICAL CONTROL; DISEASE CONTROL; HOST QUALITY; MOSQUITO;

AEDES AEGYPTI; ANOPHELES GAMBIAE; ANOPHELES GAMBIAE SENSU STRICTO; ARTICLE; BIOASSAY; NONHUMAN; SKIN ODOR; AEDES; ANIMAL; DRUG EFFECTS; HUMAN; ODOR;

AEDES AEGYPTI; ANOPHELES GAMBIAE; CULICIDAE; DIPTERA;

AEDES; ANIMALS; ANOPHELES GAMBIAE; HUMANS; INSECT REPELLENTS; ODORS;

EID: 84921762694     PISSN: 0269283X     EISSN: 13652915     Source Type: Journal    
DOI: 10.1111/mve.12061     Document Type: Article

References (44)

1. Achee, N.L., Bangs, M.J., Farlow, R. et al. (2012) Spatial repellents: from discovery and development to evidence-based validation. Malaria Journal, 11, 164.
2. Amer, A. & Mehlhorn, H. (2006) Repellency effect of forty-one essential oils against Aedes, Anopheles and Culex mosquitoes. Parasitology Research, 99, 478-490.
3. Barnard, D.R. & Xue, R.D. (2004) Laboratory evaluation of mosquito repellents against Aedes albopictus, Culex nigripalpus, and Ochlerotatus triseriatus (Diptera: Culicidae). Journal of Medical Entomology, 41, 726-730.
4. Borg-Karlson, A.-K. & Groth, I. (1986) Volatiles from the flowers of four species in the sections arachnitiformes and araneiferae of the genus Ophrys as insect mimetic attractants. Phytochemistry, 25, 1297-1299.
5. Carey, A.F., Wang, G., Su, C.-Y., Zwiebel, L.J. & Carlson, J.R. (2010) Odorant reception in the malaria mosquito Anopheles gambiae. Nature, 464, 66-71.
6. Carroll, S.P. & Loye, J. (2006) PMD, a registered botanical mosquito repellent with deet-like efficacy. Journal of the American Mosquito Control Association, 22, 507-514.
7. Cook, S.M., Khan, Z.R. & Pickett, J.A. (2007) The use of push-pull strategies in integrated pest management. Annual Review of Entomology, 52, 375-400.
8. Curran, A.M., Ramirez, C.F., Schoon, A.A. & Furton, K.G. (2007) The frequency of occurrence and discriminatory power of compounds found in human scent across a population determined by SPME-GC/MS. Journal of Chromatography B, 846, 86-97.
9. Debboun, M. & Strickman, D. (2013) Insect repellents and associated personal protection for a reduction in human disease. Medical and Veterinary Entomology, 27, 1-9.
10. Debboun, M., Frances, S. & Strickman, D. (eds) (2006) Insect Repellents: Principles, Methods, and Uses. CRC Press, Boca Raton, FL.
11. Dekker, T., Geier, M. & Cardé, R.T. (2005) Carbon dioxide instantly sensitizes female yellow fever mosquitoes to human skin odours. Journal of Experimental Biology, 208, 2963-2972.
12. Dogan, E.B. & Rossignol, P.A. (1999) An olfactometer for discriminating between attraction, inhibition and repellency in mosquitoes (Diptera: Culicidae). Journal of Medical Entomology, 36, 788-793.
13. Dogan, E.B., Ayres, J.W. & Rossignol, P.A. (1999) Behavioural mode of action of deet: inhibition of lactic acid attraction. Medical and Veterinary Entomology, 13, 97-100.
14. Feinsod, F.M. & Spielman, A. (1979) An olfactometer for measuring host-seeking behaviour of female Aedes aegypti (Diptera: Culicidae). Journal of Medical Entomology, 3, 282-285.
15. Gallagher, M., Wysocki, C.J., Leyden, J.J., Spielman, A.I., Sun, X. & Preti, G. (2008) Analyses of volatile organic compounds from human skin. British Journal of Dermatology, 159, 780-791.
16. Grieco, J.P., Achee, N.L., Sardelis, M.R., Chauhan, K.R. & Roberts, D.R. (2005) A novel high-throughput screening system to evaluate the behavioral response of adult mosquitoes to chemicals. Journal of the American Mosquito Control Association, 21, 404-411.
17. Healy, T.P., Copland, M.J., Cork, A., Przyborowska, A. & Halket, J.M. (2002) Landing responses of Anopheles gambiae elicited by oxocarboxylic acids. Medical and Veterinary Entomology, 16, 126-132.
18. Hwang, Y.-S., Wu, K.-H., Kumamoto, J., Axelrod, H. & Mulla, M.S. (1985) Isolation and identification of mosquito repellents in Artemisia vulgaris. Journal of Chemical Ecology, 11, 1297-1306.
19. Innocent, E., Gikonyo, N.K. & Nkunya, M.H.H. (2008) Repellency property of long chain aliphatic methyl ketones against Anopheles gambiae s.s. Tanzania Journal of Health Research, 10, 50-54.
20. Killeen, G.F. & Moore, S.J. (2012) Target product profiles for protecting against outdoor malaria transmission. Malaria Journal, 11, 17.
21. Klun, J.A., Kramer, M. & Debboun, M. (2005) A new in vitro bioassay system for discovery of novel human-use mosquito repellents. Journal of the American Mosquito Control Association, 21, 64-70.
22. Kröber, T., Kessler, S., Frei, J., Bourquin, M. & Guerin, P.M. (2010) An in vitro assay for testing mosquito repellents employing a warm body and carbon dioxide as a behavioural activator. Journal of the American Mosquito Control Association, 26, 381-386.
23. Lin, F.M. & Wilkens, W.F. (1970) Volatile flavour components of coconut meat. Journal of Food Science, 35, 538-539.
24. Logan, J.G., Birkett, M.A., Clark, S.J. etal. (2008) Identification of human-derived volatile chemicals that interfere with attraction of Aedes aegypti mosquitoes. Journal of Chemical Ecology, 34, 308-322.
25. Mahajan, S.S., Goddik, L. & Qian, M.C. (2004) Aroma compounds in sweet whey powder. Journal of Dairy Science, 87, 4057-4063.
26. Maxwell, C.A., Wakibara, J., Tho, S. & Curtis, C.F. (1998) Malaria-infective biting at different hours of the night. Medical and Veterinary Entomology, 12, 325-327.
27. Mukabana, W.R., Mweresa, C.K., Otieno, B., Omusula, P., Smallegange, R.C., van Loon, J.J.A. & Takken, W. (2012a) A novel synthetic odorant blend for trapping of malaria and other African mosquito species. Journal of Chemical Ecology, 38, 235-244.
28. Mukabana, W.R., Mweresa, C.K., Omusula, P., Orindi, B.O., Smallegange, R.C., van Loon, J.J.A. & Takken, W. (2012b) Evaluation of low density polyethylene and nylon for delivery of synthetic mosquito attractants. Parasites and Vectors, 5, 202.
29. Okumu, F.O., Killeen, G.F., Ogoma, S. etal. (2010a) Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. PLoS One, 5, e8951.
30. Okumu, F., Biswaro, L., Mbeleyela, E., Killeen, G.F., Mukabana, R. & Moore, S.J. (2010b) Using nylon strips to dispense mosquito attractants for sampling the malaria vector Anopheles gambiae s.s. Journal of Medical Entomology, 47, 274-282.
31. Park, B.-S., Choi, W.-S., Kim, J.-H., Kim, K.-H. & Lee, S.-E. (2005) Monoterpenes from thyme (Thymus vulgaris) as potential mosquito repellents. Journal of the American Mosquito Control Association, 21, 80-83.
32. Pask, G.M., Romaine, I.M. & Zwiebel, L.J. (2013) The molecular receptive range of a lactone receptor in Anopheles gambiae. Chemical Senses, 38, 19-25.
33. Penn, D.J., Oberzaucher, E., Grammer, K. etal. (2007) Individual and gender fingerprints in human body odour. Journal of the Royal Society, Interface, 4, 331-340.
34. Qiu, Y.T., van Loon, J.J.A., Takken, W., Meijerink, J. & Smid, H.M. (2006) Olfactory coding in antennal neurons of the malaria mosquito, Anopheles gambiae. Chemical Senses, 31, 845-863.
35. Smallegange, R.C., Bukovinszkiné-Kiss, G., Otieno, B., Mbadi, P., Takken, W., Mukabana, W.R. & van Loon, J.J.A. (2012) Identification of candidate volatiles that affect the behavioural response of the malaria mosquito Anopheles gambiae sensu stricto to an active kairomone blend: laboratory and semi-field assays. Physiological Entomology, 37, 60-71.
36. Spitzen, J., Spoor, C.W., Grieco, F. etal. (2013) A 3D analysis of flight behaviour of Anopheles gambiae sensu stricto malaria mosquitoes in response to human door and heat. PLoS One, 8, e62995.
37. Suer, R.A. (2011) Unravelling the malaria mosquito's sense of smell: neural and behavioural responses to human-derived compounds. PhD Thesis. Wageningen University, Wageningen.
38. Takken, W. (1991) The role of olfaction in host-seeking of mosquitoes: a review. International Journal of Tropical Insect Science, 12, 287-295.
39. Takken, W. & Knols, B.G.J. (1999) Odour-mediated behaviour of afrotropical malaria mosquitoes. Annual Review of Entomology, 44, 131-157.
40. Verhulst, N.O., Andriessen, R., Groenhagen, U. etal. (2010) Differential attraction of malaria mosquitoes to volatile blends produced by human skin bacteria. PLoS One, 5, e15829.
41. Verhulst, N.O., Qiu, Y.T., Beijleveld, H. etal. (2011) Composition of human skin microbiota affects attractiveness to malaria mosquitoes. PLoS One, 6, e28991.
42. Wang, G.R., Carey, A.F., Carlson, J.R. & Zwiebel, L.J. (2010) Molecular basis of odour coding in the malaria vector mosquito Anopheles gambiae. Proceedings of the National Academy of Sciences of the United States of America, 107, 4418-4423.
43. World Health Organization (2009) Guidelines for Efficacy Testing of Mosquito Repellents for Human Skin. WHO, Geneva. http://www.who.int/whopes/guidelines/en/ [Accessed 28 March 2014].
44. World Health Organization (2013) Guidelines for Efficacy Testing of Spatial Repellents. WHO, Geneva. http://www.who.int/whopes/guidelines/en/ [Accessed 28 March 2014].