Development and field evaluation of a synthetic mosquito lure that is more attractive than humans

PLoS ONE

Volumn 5, Issue 1, 2010, Pages

  Okumu, Fredros O ^a,b,c   Killeen, Gerry F ^a,d,e   Ogoma, Sheila ^a,c   Biswaro, Lubandwa ^a   Smallegange, Renate C ^g   Mbeyela, Edgar ^a   Titus, Emmanuel ^a   Munk, Cristina ^f   Ngonyani, Hassan ^a   Takken, Willem ^g   Mshinda, Hassan ^a   Mukabana, Wolfgang R ^b   Moore, Sarah J ^a,c,d  

^a IFAKARA HEALTH INSTITUTE   (Tanzania)

^b UNIVERSITY OF NAIROBI   (Kenya)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d DURHAM UNIVERSITY   (United Kingdom)

^e LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^f Plant Breeding and Genetics Section in the School of Integrative Plant Science   (United States)

^g WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CARBON DIOXIDE; CARBOXYLIC ACID;

ADULT; ARTICLE; CONTROLLED STUDY; FIELD EXPERIMENT; HUMAN; MALE; MOSQUITO; NONHUMAN; ODOR;

ANIMALS; EVALUATION STUDIES AS TOPIC; HOST-PARASITE INTERACTIONS; HUMANS; MOSQUITO CONTROL;

EID: 77749251833     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008951     Document Type: Article

References (34)

1. Zwiebel LJ, Takken W (2004) Olfactory regulation of mosquito-host interactions. Insect Biochem Mol Biol 34: 645-652.
2. Gillies MT, Coetzee M (1987) A supplement of the Anophelinae of Africa South of the Sahara (Afrotropical region). Johannesburg: South African Medical Research Institute.
3. Takken W, Knols BG (1999) Odor-mediated behavior of Afrotropical malaria mosquitoes. Annual Rev Entomol 44: 131-157.
4. Mukabana WR, Takken W, Coe R, Knols BGJ (2002) Host-specific cues cause differential attractiveness of Kenyan men to the African malaria vector Anopheles gambiae. Malar J 1.
5. Braks MAH, Meijerink J, Takken W (2001) The response of the malaria mosquito, Anopheles gambiae, to two components of human sweat, ammonia and L-lactic acid, in an olfactometer. Physiol Entomol 26: 142-148.
6. Gillies MT (1980) The role of Carbondioxide in host finding by mosquitoes (Diptera: culicidae): A review. Bull Entomol 70: 525-532.
7. Acree F, Turner RB, Gouck HK, Beroza M, Smith N (1968) L-Lactic Acid: A mosquito attractant isolated from humans. Science 161: 1346-1347.
8. Cork A, Park KC (1996) Identification of Electrophysiologically active compounds for the malaria mosquito, Anopheles gambiae, in human sweat extracts. Med Vet Entomol 10: 269-272.
9. Logan JG, Birkett MA (2007) Semiochemicals for biting fly control: their identification and exploitation. Pest Management Science 63: 647-657.
10. Bernier UR, Kline DL, Allan SA, Barnard DR (2007) Laboratory comparison of Aedes aegypti attraction to human odors and to synthetic human odor compounds and blends J Am Mos Cont Assoc 23: 288-293.
11. Bernier UR, Kline DL, Posey KH, Booth MM, Yost RA, et al. (2003) Synergistic attraction of Aedes aegypti (L.) to binary blends of L-lactic acid and acetone, dichloromethane, or dimethyl disulfide J Med Entomol 40: 653-656.
12. Smallegange RC, Qiu YT, Loon J, Takken W (2005) Synergism between ammonia, lactic acid and carboxylic acids as kairomones in the host-seeking behaviour of the malaria mosquito Anopheles gambiae sensu stricto (Diptera: Culicidae). Chem Senses 30: 145-152.
13. Qiu YT, Smallegange RC, ter Braak CJF, Spitzen J, Van Loon JJA, et al. (2007) Attractiveness of MM-X Traps Baited with Human or Synthetic Odor to Mosquitoes (Diptera: Culicidae) in The Gambia. J Med Entomol 44.
14. Krockel U, Rose A, Eiras AE, Geier M (2006) New tools for surveillance of adult yellow fever mosquitoes: comparison of trap catches with human landing rates in an urban environment. J Am Mosq Cont Assoc 22: 229-238.
15. Smallegange RC, Qiu YT, Kiss GB, Vanloon JJA, Takken W (2009) The effect of aliphatic carboxylic acids on olfaction-based host seeking of the malaria mosquito Anopheles gambiae sensu stricto (Diptera: Culicidae). J Chem Ecol. pp 1-11.
16. Ferguson HM, Ng'habi KR, Walder T, Kadungula D, Moore SJ, et al. (2008) Establishment of a large semi-field system for experimental study of African malaria vector ecology and control in Tanzania. Malar J 7: 158.
17. Smallegange RC, Qiu YT, Kiss GB, Vanloon JJA, Takken W (2009) The effect of aliphatic carboxylic acids on olfaction-based host seeking of the malaria mosquito Anopheles gambiae sensu stricto (Diptera: Culicidae). Journal of Chemical Ecology. pp 1-11.
18. Smallegange RC, Qiu YT, Loon J, Takken W (2005) Synergism between ammonia, lactic acid and carboxylic acids as kairomones in the host-seeking behaviour of the malaria mosquito Anopheles gambiae sensu stricto (Diptera: Culicidae). Chemical senses 30: 145-152.
19. Njiru BN, Mukabana RW, Takken W, Knols BGJ (2006) Trapping of the malaria vector Anopheles gambiae with odour baited MM-X traps in semi field conditions in western Kenya. Malar J 5.
20. Killeen GFea (2007) Hybrid promotion strategies combining targeted public subsidies with private sector delivery achieve high bednet coverage and reduced malaria transmission in Kilombero Valley, Southern Tanzania. BMC Infect Dis 7.
21. Okumu FO, Biswaro L, Mbeyela E, Killeen GF, Mukabana WR, et al. (In Press) Using nylon strips to dispense mosquito attractants for sampling the malaria vector Anopheles gambiae s.s. J Med Entomol.
22. Scott JA, Brogdon WG, Collins FH (1993) Identification of single specimens of the Anopheles gambiae complex by the polymerase chain reaction. Am J Trop Med Hyg 49: 520.
23. Silva IM, Eiras Á, Kline DL, Bernier UR (2005) Laboratory evaluation of mosquito traps baited with a synthetic human odor blend to capture Aedes aegypti. J Am Mosq Cont Assoc 21: 229-233.
24. Gillies MT, Wilkes TJ (1972) The range of attraction of animal baits and carbon dioxide for mosquitoes. Studies in a freshwater area of West Africa. Bull Entomol Res 61: 389-404.
25. Silver JB (2008) Mosquito Ecology: Field Sampling Methods. London: Springer.
26. Cook SM, Khan ZR, Pickett JA (2007) The Use of Push-Pull Strategies in Integrated Pest Management. Annual Rev Entomol 52: 375-400.
27. Khan ZR, Pickett JA, van den Berg J, Wadhams LJ, Woodcock CM (2000) Exploiting chemical ecology and species diversity: stem borer and striga control for maize and sorghum in Africa. Pest Management Science 56: 957-962.
28. Vale GA, Lovemore DF, Flint S, Cockbill GF (1988) Odour-baited targets to control tsetse flies, Glossina spp.(Diptera: Glossinidae), in Zimbabwe. Bull Entomol Res 78: 31-49.
29. Killeen GF, Smith TA, Ferguson HM, Mshinda H, Abdulla S, et al. (2007) Preventing childhood malaria in Africa by protecting adults from mosquitoes with insecticide-treated nets. PloS Med 4: e229.
30. Gillies MT, Wilkes TJ (1972) The range of attraction of animal baits and carbon dioxide for mosquitoes. Studies in a freshwater area of West Africa. Bull Entomol Res 61: 389-404.
31. Woolhouse MEJ, Dye C, Etard JF, Smith T, Charlwood JD, et al. (1997) Heterogeneities in the transmission of infectious agents: implications for the design of control programs. Proc Natl Acad Sci USA 94: 338-342.
32. Smith DL, Dushoff J, McKenzie FE (2004) The risk of mosquito born infection in a heterogeneous environment. Plos Biol 2e368.
33. Pates H, Curtis C (2005) Mosquito behavior and Vector Control. Annual Rev Entomol 50: 53-70.
34. Hemingway J, Field L, Vontas J (2002) An overview of insecticide resistance. Science 298: 96-97.