Culture medium of bone marrow-derived human mesenchymal stem cells effects lymphatic endothelial cells and tumor lymph vessel formation

Oncology Letters

Volumn 9, Issue 3, 2015, Pages 1221-1226

  Zhan, Jie ^a   Li, Yahong ^b   Yu, Jing ^a   Zhao, Yuanyaun ^a   Cao, Wenming ^a   Ma, Jie ^a   Sun, Xiaoxian ^a   Sun, Li ^a   Qian, Hui ^a   Zhu, Wei ^a   Xu, Wenrong ^a  

^a JIANGSU UNIVERSITY   (China)

^b WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Lymph vessel; Mesenchymal stem cell; Tumor growth

Indexed keywords

HOMEODOMAIN PROTEIN; PODOPLANIN; PROSPERO HOMEOBOX PROTEIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 3;

ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LYMPHANGIOGENESIS; MTT ASSAY; PROTEIN EXPRESSION; TUBE FORMATION; WESTERN BLOTTING; WOUND HEALING;

EID: 84921747478     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2015.2868     Document Type: Article

References (24)

1. Lin SY, Dolfi SC, Amiri S, et al: P53 regulates the migration of mesenchymal stromal cells in response to the tumor microenvironment through both CXCL12-dependent and -independent mechanisms. Int J Oncol 43: 1817-1823, 2013.
2. Chaturvedi P, Gilkes DM, Wong CC, et al: Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Invest 123: 189-205, 2013.
3. Lin R, Ma H, Ding Z, Shi W, Qian W, Song J and Hou X: Bone marrow-derived mesenchymal stem cells favor the immunosuppressive T cells skewing in a Helicobacter pylori model of gastric cancer. Stem Cells Dev 22: 2836-2848, 2013.
4. El-Haibi CP, Bell GW, Zhang J, et al: Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A 109: 17460-17465, 2012.
5. Zhang P, Dong L, Yan K, et al: CXCR4-mediated osteosarcoma growth and pulmonary metastasis is promoted by mesenchymal stem cells through VEGF. Oncol Rep 30: 1753-1761, 2013.
6. Jung Y, Kim JK, Shiozawa Y, et al: Recruitment of mesenchymal stem cells into prostate tumors promotes metastasis. Nat Commun 4: 1795, 2013.
7. Zheng W, Aspelund A and Alitalo K: Lymphangiogenic factors, mechanisms, and applications. J Clin Invest 124: 878-887, 2014.
8. Karaman S and Detmar M: Mechanisms of lymphatic metastasis. J Clin Invest 124: 922-928, 2014.
9. Stacker SA, Williams SP, Karnezis T, Shayan R, Fox SB and Achen MG: Lymphangiogenesis and lymphatic vessel remodelling in cancer. Nat Rev Cancer 14: 159-172, 2014.
10. + hepatocarcinoma ascites syngeneic cell lines mediated by JNK signaling pathway in vitro and in vivo. Biomed Pharmacother 67: 337-345, 2013.
11. Eklund L, Bry M and Alitalo K: Mouse models for studying angiogenesis and lymphangiogenesis in cancer. Mol Oncol 7: 259-282, 2013.
12. Matsumoto M, Roufail S, Inder R, et al: Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis. Clin Exp Metastasis 30: 819-832, 2013.
13. Yu JW, Wu SH, Lu RQ, et al: Expression and significances of contactin-1 in human gastric cancer. Gastroenterol Res Pract 2013: 210205, 2013.
14. Xu ZY, Yu QM, Du YA, et al: Knockdown of long non-coding RNA HOTAIR supresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancer. Int J Biol Sci 9: 587-597, 2013.
15. Singh N, Tiem M, Watkins R, et al: Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity. Blood 121: 4242-4249, 2013.
16. Su JL, Yang PC, Shih JY, et al: The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell 9: 209-223, 2006.
17. + ovarian cancer stem cells by regulating epithelial-mesenchymal transition. J Ovarian Res 6: 50, 2013.
18. Zhu W, Huang L, Li Y, et al: Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo. Cancer Lett 315: 28-37, 2012.
19. Zhu W, Huang L, Li Y, et al: Mesenchymal stem cell-secreted soluble signaling molecules potentiate tumor growth. Cell Cycle 10: 3198-3207, 2011.
20. Goldstein RH, Reagan MR, Anderson K, Kaplan DL and Rosenblatt M: Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promoes bone metastasis. Cancer Res 70: 10044-10050, 2010.
21. Karnoub AE, Dash AB, Vo AP, et al: Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449: 557-563, 2007.
22. Muehlberg FL, Song YH, Krohn A, et al: Tissue-resident stem cells promote breast cancer growth and metastasis. Carcinogenesis 30: 589-597, 2009.
23. Lin JT, Wang JY, Chen MK, Chen HC, Chang TH, Su BW and Chang PJ: Colon cancer mesenchymal stem cells modulate the tumorigenicity of colon cancer through interleukin 6. Exp Cell Res 319: 2216-2229, 2013.
24. Li GC, Ye QH, Xue YH, et al: Human mesenchymal stem cells inhibit metastasis of a hepatocellular carcinoma model using the MHCC97-H cell line. Cancer Sci 101: 2546-2553, 2010.