메뉴 건너뛰기




Volumn 94, Issue 10, 2014, Pages 1134-1146

Activin A balance regulates epithelial invasiveness and tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; FOLLISTATIN; MATRIX METALLOPROTEINASE; NEUTRALIZING ANTIBODY; SHORT HAIRPIN RNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UVOMORULIN; ACTIVIN;

EID: 84921737878     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2014.97     Document Type: Article
Times cited : (22)

References (57)
  • 1
    • 24644495693 scopus 로고    scopus 로고
    • The role of Smad signaling in hematopoiesis
    • Larsson J, Karlsson S. The role of Smad signaling in hematopoiesis. Oncogene 2005;24:5676-5692.
    • (2005) Oncogene , vol.24 , pp. 5676-5692
    • Larsson, J.1    Karlsson, S.2
  • 2
    • 0034719412 scopus 로고    scopus 로고
    • Activin-and nodal-related factors control antero-posterior patterning of the zebrafish embryo
    • Thisse B, Wright CV, Thisse C. Activin-and nodal-related factors control antero-posterior patterning of the zebrafish embryo. Nature 2000;403:425-428.
    • (2000) Nature , vol.403 , pp. 425-428
    • Thisse, B.1    Wright, C.V.2    Thisse, C.3
  • 3
    • 0034862866 scopus 로고    scopus 로고
    • Overexpression of activin A in stage IV colorectal cancer
    • Wildi S, Kleeff J, Maruyama H, et al. Overexpression of activin A in stage IV colorectal cancer. Gut 2001;49:409-417.
    • (2001) Gut , vol.49 , pp. 409-417
    • Wildi, S.1    Kleeff, J.2    Maruyama, H.3
  • 4
    • 3142543334 scopus 로고    scopus 로고
    • An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors
    • Harrison CA, Gray PC, Fischer WH, et al. An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors. J Biol Chem 2004;279:28036-28044.
    • (2004) J Biol Chem , vol.279 , pp. 28036-28044
    • Harrison, C.A.1    Gray, P.C.2    Fischer, W.H.3
  • 6
    • 33750573332 scopus 로고    scopus 로고
    • Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo
    • Andl CD, Fargnoli BB, Okawa T, et al. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. Cancer Res 2006;66:9878-9885.
    • (2006) Cancer Res , vol.66 , pp. 9878-9885
    • Andl, C.D.1    Fargnoli, B.B.2    Okawa, T.3
  • 7
    • 44949144789 scopus 로고    scopus 로고
    • Activin A increases invasiveness of endometrial cells in an in vitro model of human peritoneum
    • Ferreira MC, Witz CA, Hammes LS, et al. Activin A increases invasiveness of endometrial cells in an in vitro model of human peritoneum. Mol Hum Reprod 2008;14:301-307.
    • (2008) Mol Hum Reprod , vol.14 , pp. 301-307
    • Ferreira, M.C.1    Witz, C.A.2    Hammes, L.S.3
  • 8
    • 84858208747 scopus 로고    scopus 로고
    • CD44 upregulation in E-cadherin-negative esophageal cancers results in cell invasion
    • Le Bras GF, Allison GL, Richards NF, et al. CD44 upregulation in E-cadherin-negative esophageal cancers results in cell invasion. PLoS One 2011;6:e27063.
    • (2011) PLoS One , vol.6 , pp. e27063
    • Le Bras, G.F.1    Allison, G.L.2    Richards, N.F.3
  • 9
    • 24744446473 scopus 로고    scopus 로고
    • Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells
    • Burdette JE, Jeruss JS, Kurley SJ, et al. Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells. Cancer Res 2005;65:7968-7975.
    • (2005) Cancer Res , vol.65 , pp. 7968-7975
    • Burdette, J.E.1    Jeruss, J.S.2    Kurley, S.J.3
  • 10
    • 0034454964 scopus 로고    scopus 로고
    • Activin effects on neoplastic proliferation of human pituitary tumors
    • Danila DC, Inder WJ, Zhang X, et al. Activin effects on neoplastic proliferation of human pituitary tumors. J Clin Endocrinol Metab 2000;85:1009-1015.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1009-1015
    • Danila, D.C.1    Inder, W.J.2    Zhang, X.3
  • 12
    • 1842839881 scopus 로고    scopus 로고
    • Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1
    • Ho J, de Guise C, Kim C, et al. Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1. Cell Signal 2004;16:693-701.
    • (2004) Cell Signal , vol.16 , pp. 693-701
    • Ho, J.1    De Guise, C.2    Kim, C.3
  • 13
    • 0031846251 scopus 로고    scopus 로고
    • Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer
    • Kleeff J, Ishiwata T, Friess H, et al. Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer. Int J Cancer 1998;77:860-868.
    • (1998) Int J Cancer , vol.77 , pp. 860-868
    • Kleeff, J.1    Ishiwata, T.2    Friess, H.3
  • 14
    • 0030726297 scopus 로고    scopus 로고
    • Expression and localization of activin subunits and Follistatins in tissues from men with high grade prostate cancer
    • Thomas TZ, Wang H, Niclasen P, et al. Expression and localization of activin subunits and Follistatins in tissues from men with high grade prostate cancer. J Clin Endocrinol Metab 1997;82:3851-3858.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3851-3858
    • Thomas, T.Z.1    Wang, H.2    Niclasen, P.3
  • 15
    • 0036357368 scopus 로고    scopus 로고
    • Role of inhibins and activins in ovarian cancer
    • Woodruff TK. Role of inhibins and activins in ovarian cancer. Cancer Treat Res 2002;107:293-302.
    • (2002) Cancer Treat Res , vol.107 , pp. 293-302
    • Woodruff, T.K.1
  • 16
    • 38049152697 scopus 로고    scopus 로고
    • Activin a causes cancer cell aggressiveness in esophageal squamous cell carcinoma cells
    • Yoshinaga K, Yamashita K, Mimori K, et al. Activin a causes cancer cell aggressiveness in esophageal squamous cell carcinoma cells. Ann Surg Oncol 2008;15:96-103.
    • (2008) Ann Surg Oncol , vol.15 , pp. 96-103
    • Yoshinaga, K.1    Yamashita, K.2    Mimori, K.3
  • 17
    • 35048875855 scopus 로고    scopus 로고
    • TGF-beta signaling: A tale of two responses
    • Rahimi RA, Leof EB. TGF-beta signaling: a tale of two responses. J Cell Biochem 2007;102:593-608.
    • (2007) J Cell Biochem , vol.102 , pp. 593-608
    • Rahimi, R.A.1    Leof, E.B.2
  • 18
    • 0042307513 scopus 로고    scopus 로고
    • The two faces of transforming growth factor beta in carcinogenesis
    • Roberts AB, Wakefield LM. The two faces of transforming growth factor beta in carcinogenesis. Proc Natl Acad Sci USA 2003;100: 8621-8623.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8621-8623
    • Roberts, A.B.1    Wakefield, L.M.2
  • 19
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L, Yuan X, Sharkis SJ. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 2006; 24:1476-1486.
    • (2006) Stem Cells , vol.24 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 20
    • 79551631724 scopus 로고    scopus 로고
    • Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem cells
    • Katoh M. Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem cells. Curr Pharm Biotechnol 2011;12:160-170.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 160-170
    • Katoh, M.1
  • 21
    • 77956029924 scopus 로고    scopus 로고
    • The more things changey. The more things change: Developmental plasticity of tumor-initiating mammary epithelial cells
    • Lewis MT. The more things changey. The more things change: developmental plasticity of tumor-initiating mammary epithelial cells. Breast Cancer Res 2010;12:101.
    • (2010) Breast Cancer Res , vol.12 , pp. 101
    • Lewis, M.T.1
  • 22
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
    • Kowanetz M, Valcourt U, Bergstrom R, et al. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol Cell Biol 2004;24:4241-4254.
    • (2004) Mol Cell Biol , vol.24 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergstrom, R.3
  • 23
    • 33645508543 scopus 로고    scopus 로고
    • Id proteins: Novel targets of activin action, which regulate epidermal homeostasis
    • Rotzer D, Krampert M, Sulyok S, et al. Id proteins: novel targets of activin action, which regulate epidermal homeostasis. Oncogene 2006;25:2070-2081.
    • (2006) Oncogene , vol.25 , pp. 2070-2081
    • Rotzer, D.1    Krampert, M.2    Sulyok, S.3
  • 24
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002;30:207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 25
    • 77958590561 scopus 로고    scopus 로고
    • Ontology-based meta-analysis of global collections of high-throughput public data
    • Kupershmidt I, Su QJ, Grewal A, et al. Ontology-based meta-analysis of global collections of high-throughput public data. PLoS One 2010;29:e13066.
    • (2010) PLoS One , vol.29 , pp. e13066
    • Kupershmidt, I.1    Su, Q.J.2    Grewal, A.3
  • 26
    • 77950888839 scopus 로고    scopus 로고
    • Hypoxia activates the cyclooxy-genase-2-prostaglandin e synthase axis
    • Lee JJ, Natsuizaka M, Ohashi S, et al. Hypoxia activates the cyclooxy-genase-2-prostaglandin E synthase axis. Carcinogenesis 2010;31: 427-434.
    • (2010) Carcinogenesis , vol.31 , pp. 427-434
    • Lee, J.J.1    Natsuizaka, M.2    Ohashi, S.3
  • 27
    • 79955495946 scopus 로고    scopus 로고
    • Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes
    • Su H, Hu N, Yang HH, et al. Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes. Clin Cancer Res 2011;17: 2955-2966.
    • (2011) Clin Cancer Res , vol.17 , pp. 2955-2966
    • Su, H.1    Hu, N.2    Yang, H.H.3
  • 28
    • 34548508972 scopus 로고    scopus 로고
    • The activin A-Follistatin system: Potent regulator of human extracellular matrix mineralization
    • Eijken M, Swagemakers S, Koedam M, et al. The activin A-Follistatin system: potent regulator of human extracellular matrix mineralization. FASEB J 2007;21:2949-2960.
    • (2007) FASEB J , vol.21 , pp. 2949-2960
    • Eijken, M.1    Swagemakers, S.2    Koedam, M.3
  • 29
    • 0028093079 scopus 로고
    • Morphological differences in Xenopus embryonic mesodermal cells are specified as an early response to distinct threshold concentrations of activin
    • Symes K, Yordán C, Mercola M. Morphological differences in Xenopus embryonic mesodermal cells are specified as an early response to distinct threshold concentrations of activin. Development 1994;120: 2339-2346.
    • (1994) Development , vol.120 , pp. 2339-2346
    • Symes, K.1    Yordán, C.2    Mercola, M.3
  • 30
    • 0025166072 scopus 로고
    • Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate
    • Green JB, Smith JC. Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature 1990;347:391-394.
    • (1990) Nature , vol.347 , pp. 391-394
    • Green, J.B.1    Smith, J.C.2
  • 31
    • 0026442926 scopus 로고
    • Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
    • Green JB, New HV, Smith JC. Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 1992;71: 731-739.
    • (1992) Cell , vol.71 , pp. 731-739
    • Green, J.B.1    New, H.V.2    Smith, J.C.3
  • 32
    • 42149123306 scopus 로고    scopus 로고
    • More than one way to skin
    • Fuchs E, Horsley V. More than one way to skin. Genes Dev 2008;22: 976-985.
    • (2008) Genes Dev , vol.22 , pp. 976-985
    • Fuchs, E.1    Horsley, V.2
  • 33
    • 0036558278 scopus 로고    scopus 로고
    • Stem cells of the oesophageal epithelium
    • Seery JP. Stem cells of the oesophageal epithelium. J Cell Sci 2002;115:1783-1789.
    • (2002) J Cell Sci , vol.115 , pp. 1783-1789
    • Seery, J.P.1
  • 35
  • 36
    • 1842847888 scopus 로고    scopus 로고
    • Clinical significance of the expression of activin A in esophageal carcinoma
    • Yoshinaga K, Mimori K, Yamashita K, et al. Clinical significance of the expression of activin A in esophageal carcinoma. Int J Oncol 2003;22:75-80.
    • (2003) Int J Oncol , vol.22 , pp. 75-80
    • Yoshinaga, K.1    Mimori, K.2    Yamashita, K.3
  • 37
    • 4444298259 scopus 로고    scopus 로고
    • N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma
    • Yoshinaga K, Inoue H, Utsunomiya T, et al. N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma. Clin Cancer Res 2004;10:5702-5707.
    • (2004) Clin Cancer Res , vol.10 , pp. 5702-5707
    • Yoshinaga, K.1    Inoue, H.2    Utsunomiya, T.3
  • 38
    • 54849187300 scopus 로고    scopus 로고
    • Activin A enhances MMP-7 activity via the transcription factor AP-1 in an eso-phageal squamous cell carcinoma cell line
    • Yoshinaga K, Mimori K, Inoue H, et al. Activin A enhances MMP-7 activity via the transcription factor AP-1 in an eso-phageal squamous cell carcinoma cell line. Int J Oncol 2008;33: 453-459.
    • (2008) Int J Oncol , vol.33 , pp. 453-459
    • Yoshinaga, K.1    Mimori, K.2    Inoue, H.3
  • 39
    • 0030609894 scopus 로고    scopus 로고
    • TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    • Sanford LP, Ormsby I, Gittenberger-de Groot AC, et al. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 1997;124:2659-2670.
    • (1997) Development , vol.124 , pp. 2659-2670
    • Sanford, L.P.1    Ormsby, I.2    Gittenberger-De Groot, A.C.3
  • 40
    • 0037374547 scopus 로고    scopus 로고
    • Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers
    • Hempen PM, Zhang L, Bansal RK, et al. Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res 2003;63: 994-999.
    • (2003) Cancer Res , vol.63 , pp. 994-999
    • Hempen, P.M.1    Zhang, L.2    Bansal, R.K.3
  • 41
    • 0035853078 scopus 로고    scopus 로고
    • ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma
    • Su GH, Bansal R, Murphy KM, et al. ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma. Proc Natl Acad Sci USA 2001;98:3254-3257.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3254-3257
    • Su, G.H.1    Bansal, R.2    Murphy, K.M.3
  • 42
    • 42949160593 scopus 로고    scopus 로고
    • The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers
    • Kodach LL, Wiercinska E, de Miranda NF, et al. The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers. Gastroenterology 2008;134:1332-1341.
    • (2008) Gastroenterology , vol.134 , pp. 1332-1341
    • Kodach, L.L.1    Wiercinska, E.2    De Miranda, N.F.3
  • 43
    • 10744228797 scopus 로고    scopus 로고
    • Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells
    • Sekiya T, Adachi S, Kohu K, et al. Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells. J Biol Chem 2004;279:6840-6846.
    • (2004) J Biol Chem , vol.279 , pp. 6840-6846
    • Sekiya, T.1    Adachi, S.2    Kohu, K.3
  • 44
    • 67649234580 scopus 로고    scopus 로고
    • A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential
    • Fritzmann J, Morkel M, Besser D, et al. A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential. Gastroenterology 2009;137:165-175.
    • (2009) Gastroenterology , vol.137 , pp. 165-175
    • Fritzmann, J.1    Morkel, M.2    Besser, D.3
  • 45
    • 84925944560 scopus 로고    scopus 로고
    • Mechanisms of cancer cachexia
    • Tisdale MJ. Mechanisms of cancer cachexia. Physiol Rev 2009;330: 171-179.
    • (2009) Physiol Rev , vol.330 , pp. 171-179
    • Tisdale, M.J.1
  • 46
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massague J. TGFbeta in Cancer. Cell 2008;134:215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 47
    • 84863087905 scopus 로고    scopus 로고
    • High serum levels of Follistatin in patients with ovarian cancer
    • Ren P, Chen FF, Liu HY, et al. High serum levels of Follistatin in patients with ovarian cancer. J Int Med Res 2012;40:877-886.
    • (2012) J Int Med Res , vol.40 , pp. 877-886
    • Ren, P.1    Chen, F.F.2    Liu, H.Y.3
  • 48
    • 78649317242 scopus 로고    scopus 로고
    • Serum Follistatin in patients with prostate cancer metastatic to the bone
    • Tumminello FM, Badalamenti G, Fulfaro F, et al. Serum Follistatin in patients with prostate cancer metastatic to the bone. Clin Exp Metastasis 2010;27:549-555.
    • (2010) Clin Exp Metastasis , vol.27 , pp. 549-555
    • Tumminello, F.M.1    Badalamenti, G.2    Fulfaro, F.3
  • 49
    • 77954959913 scopus 로고    scopus 로고
    • Overexpression of activin A in oral squamous cell carcinoma: Association with poor prognosis and tumor progression
    • Chang KP, Kao HK, Liang Y, et al. Overexpression of activin A in oral squamous cell carcinoma: association with poor prognosis and tumor progression. Ann Surg Oncol 2010;17:1945-1956.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1945-1956
    • Chang, K.P.1    Kao, H.K.2    Liang, Y.3
  • 50
    • 59449086789 scopus 로고    scopus 로고
    • Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin
    • Chen M, Sinha M, Luxon BA, et al. Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin. J Biol Chem 2009;284:1484-1494.
    • (2009) J Biol Chem , vol.284 , pp. 1484-1494
    • Chen, M.1    Sinha, M.2    Luxon, B.A.3
  • 51
    • 38949172092 scopus 로고    scopus 로고
    • Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in natural killer cell-depleted SCID mice
    • Ogino H, Yano S, Kakiuchi S, et al. Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in natural killer cell-depleted SCID mice. Clin Cancer Res 2008;14:660-667.
    • (2008) Clin Cancer Res , vol.14 , pp. 660-667
    • Ogino, H.1    Yano, S.2    Kakiuchi, S.3
  • 52
    • 24044509109 scopus 로고    scopus 로고
    • Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinoctyes
    • Bamberger C, Schärer A, Antsiferova M, et al. Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinoctyes. Am J Pathol 2005;167:733-747.
    • (2005) Am J Pathol , vol.167 , pp. 733-747
    • Bamberger, C.1    Schärer, A.2    Antsiferova, M.3
  • 53
    • 34249863319 scopus 로고    scopus 로고
    • A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus
    • Saka Y, Smith JC. A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus. BMC Dev Biol 2007; 7:4.
    • (2007) BMC Dev Biol , vol.7 , pp. 4
    • Saka, Y.1    Smith, J.C.2
  • 54
    • 0033145776 scopus 로고    scopus 로고
    • Activin as a morphogen in Xenopus mesoderm induction
    • McDowell N, Gurdon JB. Activin as a morphogen in Xenopus mesoderm induction. Semin Cell Dev Biol 1999;10:311-317.
    • (1999) Semin Cell Dev Biol , vol.10 , pp. 311-317
    • McDowell, N.1    Gurdon, J.B.2
  • 55
    • 0028122987 scopus 로고
    • Activin signalling and response to a morphogen gradient
    • Gurdon JB, Harger P, Mitchell A, et al. Activin signalling and response to a morphogen gradient. Nature 1994;371:487-492.
    • (1994) Nature , vol.371 , pp. 487-492
    • Gurdon, J.B.1    Harger, P.2    Mitchell, A.3
  • 56
    • 0030476862 scopus 로고    scopus 로고
    • Signalling by TGF-family members: Short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin
    • Jones CM, Armes N, Smith JC. Signalling by TGF-family members: short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin. Curr. Biol. 1996;6:1468-1475.
    • (1996) Curr. Biol. , vol.6 , pp. 1468-1475
    • Jones, C.M.1    Armes, N.2    Smith, J.C.3
  • 57
    • 0032516088 scopus 로고    scopus 로고
    • Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
    • Crease DJ, Dyson S, Gurdon JB. Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression. Proc Natl Acad Sci USA 1998;95:4398-4403.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4398-4403
    • Crease, D.J.1    Dyson, S.2    Gurdon, J.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.