-
3
-
-
0346455759
-
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
-
Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK, et al. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet 2004;36:63-8.
-
(2004)
Nat Genet
, vol.36
, pp. 63-68
-
-
Liu, G.1
Parant, J.M.2
Lang, G.3
Chau, P.4
Chavez-Reyes, A.5
El-Naggar, A.K.6
-
4
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L, et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 1999;104:263-9.
-
(1999)
J Clin Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
-
5
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
6
-
-
0028849274
-
p21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman T, Kinzler KW, Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 1995;55:5187-90.
-
(1995)
Cancer Res
, vol.55
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
7
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998;282:1497-501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
-
8
-
-
0029811984
-
Genetic determinants of p53-induced apoptosis and growth arrest
-
Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B. Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 1996;10:1945-52.
-
(1996)
Genes Dev
, vol.10
, pp. 1945-1952
-
-
Polyak, K.1
Waldman, T.2
He, T.C.3
Kinzler, K.W.4
Vogelstein, B.5
-
9
-
-
0028978183
-
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
-
Deng C, Zhang P, Harper JW, Elledge SJ, Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995;82:675-84.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
10
-
-
0035810054
-
Regulation of the G2/M transition by p53
-
Taylor WR, Stark GR. Regulation of the G2/M transition by p53. Oncogene 2001;20:1803-15.
-
(2001)
Oncogene
, vol.20
, pp. 1803-1815
-
-
Taylor, W.R.1
Stark, G.R.2
-
11
-
-
0032743748
-
Mechanisms of G2 arrest in response to overexpression of p53
-
Taylor WR, DePrimo SE, Agarwal A, Agarwal ML, Schönthal AH, Katula KS, et al. Mechanisms of G2 arrest in response to overexpression of p53. Mol Biol Cell 1999;10:3607-22.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3607-3622
-
-
Taylor, W.R.1
DePrimo, S.E.2
Agarwal, A.3
Agarwal, M.L.4
Schönthal, A.H.5
Katula, K.S.6
-
13
-
-
9744250223
-
DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: One involves direct binding to the cdc25C promoter
-
St Clair S, Giono L, Varmeh-Ziaie S, Resnick-Silverman L, Liu WJ, Padi A, et al. DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter. Mol Cell 2004;16:725-36.
-
(2004)
Mol Cell
, vol.16
, pp. 725-736
-
-
St Clair, S.1
Giono, L.2
Varmeh-Ziaie, S.3
Resnick-Silverman, L.4
Liu, W.J.5
Padi, A.6
-
14
-
-
0033616501
-
GADD45 induction of a G2/M cell cycle checkpoint
-
Wang XW, Zhan Q, Coursen JD, Khan MA, Kontny HU, Yu L, et al. GADD45 induction of a G2/M cell cycle checkpoint. Proc Natl Acad Sci U S A 1999;96:3706-11.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3706-3711
-
-
Wang, X.W.1
Zhan, Q.2
Coursen, J.D.3
Khan, M.A.4
Kontny, H.U.5
Yu, L.6
-
15
-
-
0031931414
-
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
-
Lanni JS, Jacks T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol 1998;18:1055-64.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1055-1064
-
-
Lanni, J.S.1
Jacks, T.2
-
16
-
-
0032952584
-
p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption
-
Stewart ZA, Leach SD, Pietenpol JA. p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption. Mol Cell Biol 1999;19:205-15.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 205-215
-
-
Stewart, Z.A.1
Leach, S.D.2
Pietenpol, J.A.3
-
17
-
-
0035886017
-
Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells
-
Andreassen PR, Lacroix FB, Lohez OD, Margolis RL. Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells. Cancer Res 2001;61:7660-8.
-
(2001)
Cancer Res
, vol.61
, pp. 7660-7668
-
-
Andreassen, P.R.1
Lacroix, F.B.2
Lohez, O.D.3
Margolis, R.L.4
-
18
-
-
0034767429
-
Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
-
Andreassen PR, Lohez OD, Lacroix FB, Margolis RL. Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol Biol Cell 2001;12:1315-28.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 1315-1328
-
-
Andreassen, P.R.1
Lohez, O.D.2
Lacroix, F.B.3
Margolis, R.L.4
-
19
-
-
0037162455
-
Multiple centrosomes arise from tetraploidy checkpoint failure andmitotic centrosome clusters in p53 and RB pocket protein-compromised cells
-
Borel F, Lohez OD, Lacroix FB, Margolis RL. Multiple centrosomes arise from tetraploidy checkpoint failure andmitotic centrosome clusters in p53 and RB pocket protein-compromised cells. Proc Natl Acad Sci U S A 2002;99:9819-24.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9819-9824
-
-
Borel, F.1
Lohez, O.D.2
Lacroix, F.B.3
Margolis, R.L.4
-
20
-
-
0024406882
-
Model for the genetic evolution of human solid tumors
-
Shackney SE, Smith CA, Miller BW, Burholt DR, Murtha K, Giles HR, et al. Model for the genetic evolution of human solid tumors. Cancer Res 1989;49:3344-54.
-
(1989)
Cancer Res
, vol.49
, pp. 3344-3354
-
-
Shackney, S.E.1
Smith, C.A.2
Miller, B.W.3
Burholt, D.R.4
Murtha, K.5
Giles, H.R.6
-
21
-
-
1642326716
-
Phosphorylation of histone H3: A balancing act between chromosome condensation and transcriptional activation
-
Nowak SJ, Corces VG. Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation. Trends Genet 2004;20:214-20.
-
(2004)
Trends Genet
, vol.20
, pp. 214-220
-
-
Nowak, S.J.1
Corces, V.G.2
-
22
-
-
0035910458
-
p130/E2F4 binds to and represses the cdc2 promoter in response to p53
-
Taylor WR, Schonthal AH, Galante J, Stark GR. p130/E2F4 binds to and represses the cdc2 promoter in response to p53. J Biol Chem 2001;276:1998-2006.
-
(2001)
J Biol Chem
, vol.276
, pp. 1998-2006
-
-
Taylor, W.R.1
Schonthal, A.H.2
Galante, J.3
Stark, G.R.4
-
23
-
-
13544254815
-
Topoisomerase II: Untangling its contribution at the centromere
-
Porter AC, Farr CJ. Topoisomerase II: untangling its contribution at the centromere. Chromosome Res 2004;12:569-83.
-
(2004)
Chromosome Res
, vol.12
, pp. 569-583
-
-
Porter, A.C.1
Farr, C.J.2
-
24
-
-
23044502867
-
Chemotherapy compounds in cervical cancer cells primed by reconstitution of p53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: Opposite effect of siRNA in combination with different drugs
-
Koivusalo R, Krausz E, Helenius H, Hietanen S. Chemotherapy compounds in cervical cancer cells primed by reconstitution of p53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs. Mol Pharmacol 2005;68:372-82.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 372-382
-
-
Koivusalo, R.1
Krausz, E.2
Helenius, H.3
Hietanen, S.4
-
25
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007;445:656-60.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
-
26
-
-
84862124987
-
p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer
-
Jackson JG, Pant V, Li Q, Chang L, Quintás-Cardama A, Garza D, et al. p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell 2012;21:793-806.
-
(2012)
Cancer Cell
, vol.21
, pp. 793-806
-
-
Jackson, J.G.1
Pant, V.2
Li, Q.3
Chang, L.4
Quintás-Cardama, A.5
Garza, D.6
-
27
-
-
84884716320
-
p53 in breast cancer subtypes and new insights into response to chemotherapy
-
Bertheau P, Lehmann-Che J, Varna M, Dumay A, Poirot B, Porcher R, et al. p53 in breast cancer subtypes and new insights into response to chemotherapy. Breast 2013;22 Suppl 2:S27-9.
-
(2013)
Breast
, vol.22
, pp. S27-S29
-
-
Bertheau, P.1
Lehmann-Che, J.2
Varna, M.3
Dumay, A.4
Poirot, B.5
Porcher, R.6
-
28
-
-
0033533612
-
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
-
Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 1999;401:616-20.
-
(1999)
Nature
, vol.401
, pp. 616-620
-
-
Chan, T.A.1
Hermeking, H.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
|