Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence

Molecular Cell

Volumn 55, Issue 5, 2014, Pages 782-790

  Yang, Ming ^a,b   Haase, AstridD ^a,c   Huang, Fang Ke ^d   Coulis, Gérald ^e,f   Rivera, KeithD ^a   Dickinson, BryanC ^c,g   Chang, ChristopherJ ^c,g   Pappin, DarrylJ ^a   Neubert, ThomasA ^d   Hannon, GregoryJ ^a,c   Boivin, Benoit ^a,e,f   Tonks, NicholasK ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f MONTREAL HEART INSTITUTE   (Canada)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 2 PROTEIN; MICRORNA; PROTEIN TYROSINE PHOSPHATASE 1B; TYROSINE; ARGONAUTE PROTEIN; EIF2C2 PROTEIN, HUMAN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL AGING; GENE SILENCING; HEK293 CELL LINE; HUMAN; HUMAN CELL; ONCOGENE H RAS; OXIDATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; CELL LINE; CHEMISTRY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ARGONAUTE PROTEINS; CELL AGING; CELL LINE; GENE SILENCING; HUMANS; MICRORNAS; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RAS PROTEINS; REACTIVE OXYGEN SPECIES; TYROSINE;

EID: 84921692079     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.07.018     Document Type: Article

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