Seduction Super-Responders and Hyper-Trusters: The Biology of Affiliative Behavior

Pathological Altruism

Volumn , Issue , 2012, Pages

  Pessin, Karol M ^a  

^a Westlake Village   (United States)

Author keywords

Altruism; CD38; Oxytocin; Seduction; Social biology; Social signals; Trust; Vasopressin

Indexed keywords

EID: 84921632720     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1093/acprof:oso/9780199738571.003.0243     Document Type: Chapter

References (89)

1. Ackerman, J. M., Goldstein, N. J., Shapiro, J. R., & Bargh, J. A. (2009). You wear me out:The vicarious depletion of self-control. Psychological Science, 20, 326-332.
2. Almeida, J. R., Mechelli, A., Hassel, S., Versace, A., Kupfer, D. J., & Phillips, M. L. (2009). Abnormally increased effective connectivity between parahippocampal gyrus and ventromedial prefrontal regions during emotion labeling in bipolar disorder. Psychiatry Research, 174, 195-201.
3. Andari, E., Duhamal, J. -R., Zalla, T., Herbrecht, E., Lebover, M., & Sirigu, A. (2010). Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proceedings of the National Academy of Science, 107, 4389-4394.
4. Aoyagi, T., Kusakawa, S., Sanbe, A., Hiroyama, M., Fujiwara Y., Yamauchi, J., & Tanoue, A. (2009). Enhanced effect of neuropeptide Y on food intake caused by blockade of the V(1A) vasopressin receptor. European Journal of Pharmacology, 622, 32-36.
5. Arnott, S.R., Singhal, A., & Goodale, M.A. (2009). An investingation of auditory contagious yawning. Cognitive, Affective & Behavioral Neuroscience 9, 335-342.
6. Bachner-Melman, R., Dina, C., Zohar, A. H., Constantini, N., Lerer, E., Hoch, S., et al. (2005). AVPR1a and SLC6A4 gene polymorphisms are associated with creative dance performance. PLoS Genetics, 1, e42.
7. Backström T, & Winberg, S. (2009). Arginine-vasotocin influence on aggressive behavior and dominance in rainbow trout. Physiology and Behavior, 96, 470-475.
8. Bastiaansen, J. A., Thioux, M., & Keysers C. (2009). Evidence for mirror systems in emotions. Philosophical Transactions of the Royal Society of London. B. Biological Sciences, 364, 2391-2404.
9. Bennis, W. M., Medin, D. L., & Bartels, D. M. (2009). The costs and benefits of calculation and moral rules. Perspectives on Psychological Science, forthcoming. Retrieved from SSRN:
10. Bozon, M., & Heran, F. (1989). Finding a spouse: A survey of how French couples meet. Population, 44, 90-121.
11. Cacioppo, J. T., Fowler, J. H., & Christakis, N. A. (2008). Alone in the crowd: The structure and spread of loneliness in a large social network. Journal of Personality and Social Psychology, 97, 977-991.
12. Caldwell, H. K., & Young, W. S., III. (2009). Persistence of reduced aggression in vasopressin 1b receptor knockout mice on a more "wild" background. Physiology and Behavior, 97, 131-134.
13. Campbell, P., Ophir, A. G., & Phelps, S. M. (2009). Central vasopressin and oxytocin receptor distributions in two species of singing mice. Journal of Comparative Neurology, 516, 321-333.
14. Chiao, J. Y., Mathur, V. A., Harada, T., & Lipke, T. (2009). Neural basis of preference for human social hierarchy versus egalitarianism. Annals of the New York Academy of Science, 1167, 174-181.
15. Choi, J. -K., & Bowles, S. (2007) The coevolution of parochial altruism and war. Science, 318, 636-640.
16. Christakis, N., & Fowler, J. (2009). Connected: The surprising power of our social networks and how they shape our lives. New York: Little, Brown.
17. Cikara M., Farnsworth R.A., Harris L.T., Fiske S.T. (2010). On the wrong side of the trolley track: neural correlates of relative social valuation. Social, Cognitive and Affective Neuroscience 5, 404-13.
18. Craig, M. C., Catani, M., Deeley, Q., Latham, R., Daly, E., Kanaan, R., et al. (2009). Altered connections on the road to psychopathy. Molecular Psychiatry, 10, 946-53, 907.
19. Crockett, M. J., Clark, L. Hauser, M. D., Robbins T. W. (2010). Serotonin selectively influences moral judgment and behavior through effects on harm aversion PNAS - USA, 107, 17433-17438.
20. Crockett, M. J., Clark, L., Lieberman, M. D., Tabibnia, G., Robbins, T.W. (2010). Emotion 10, 855-62.
21. Crowson, H. (2008, July 09). Cultural and economic conservatism: Relationships with epistemic beliefs and motives, death anxiety, and dogmatic aggression. Paper presented at the annual meeting of the ISPP 31st Annual Scientific Meeting, Sciences Po., Paris, France. Retrieved from
22. Crowson H. M. (2009). Are all conservatives alike? A study of the psychological correlates of cultural and economic conservatism. Journal of Psychology, 143, 449-63.
23. De Dreu, C. K., Greer, L. L., Handgraaf, M. J., Shalvi, S., Van Kleef, G. A., Baas, M., et al. (2010) The neuropeptide oxytocin regulates parochial altruism in intergroup conflict among humans. Science, 328, 1408-11.
24. Donaldson, Z. R., & Young, L. J. (2008). Oxytocin, vasopressin, and the neurogenetics of sociality. Science 322, 900-904. (Correction: (2009) Science 323, 1429a).
25. Ebstein, R. P., Israel, S., Lerer, E., Uzefovsky, F., Shalev, I., Gritsenko, I., et al. (2009). Arginine vasopressin and oxytocin modulate human social behavior. Annals of the New York Academy of Science, 1167, 87-102.
26. Ebstein, R. P., Salomon, I., Chew, S. -H., Zhong, S., & Knafo, A. (2010). Genetics of Human Social Behavior. Neuron, 65, 831-844.
27. Eisenberger, N. I., Liberman, M. D., & Williams, K. D. (2003). Does rejection hurt? An fMRI study of social exclusion. Science, 302, 290-292.
28. Endres, T., & Fendt, M. (2009). Aversion- vs fear-inducing properties of 2,4,5-trimethyl-3-thiazoline, a component of fox odor, in comparison with those of butyric acid. Journal of Experimental Biology, 212, 2324-2327.
29. Fast, N. J., & Tiedens, L. Z. (2010). Blame contagion: The automatic transmission of selfserving attributions. Journal of Experimental Social Psychology, 46, 97-106.
30. Fowler, J. H., & Christakis, N. A. (2008). Dynamic spread of happiness in a large social network: Longitudinal analysis over 20 years in the Framingham Heart Study. British Medical Journal, 337, a2338.
31. Frith, U., & Frith, C. (2010). The social brain: Allowing humans to boldly go where no other species has been. Philosophical Transactions of the Royal Society of London. B., 365, 165-176.
32. Gelstein, S., Yeshurun, Y., Rozenkrantz, L., Shushan, S., Frumin, I., Roth, Y., & Sobel, N. (2011). Human Tears Contain a Chemosignal. Science ePub ahead of print. doi:10.1126/science.1198331
33. Giganti, F., & Esposito Ziello, M. (2009). Contagious and spontaneous yawning in autistic and typically developing children. Current Psychology Letters, 25, 1. Retrieved from
34. Grape, C., Sandgren, M., Hansson, L., Ericson, M., & Theorell, T. (2003). Does singing promote well-being?: An empirical study of professional and amateur singers during a singing lesson. Integrative Physiological and Behavioral Science, 38, 65-74.
35. Gregory, S. G., Connelly, J. J., Towers, A. J., Johnson, J., Biscocho, D., Markunas, C. A., et al. (2009). Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. BMC Medicine, 7, 62.
36. Gwee, P. C., Tay, B. H., Brenner, S., & Venkatesh, B. (2009). Characterization of the neurohypophysial hormone gene loci in elephant shark and the Japanese lamprey: Origin of the vertebrate neurohypophysial hormone genes. BMC Evolutionary Biology, 9, 47.
37. Harr, A. L., Gilbert, V. R., & Phillips, K. A. (2009). Do dogs (Canis familiaris) show contagious yawning? Animal Cognition, 12, 833-837.
38. Hatfield, E., Rapson, R. L., & Le, Y. L. (2009). Primitive emotional contagion: Recent research. In J. Decety, and W. Ickes (Eds.), The social neuroscience of empathy. Boston, MA: MIT Press.
39. Hatton, G. I., & Wang, Y. F. (2008). Neural mechanisms underlying the milk ejection burst and reflex. Progress in Brain Research, 170, 155-166.
40. Israel, S., Lerer, E., Shalev, I., Uzefovsky, F., Riebold, M., Laiba, E., et al. (2009). The Oxytocin Receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task. PLoS ONE, 4, e5535.
41. Iwata, E., Nagai Y., & Sasaki, H. (2008). Social rank modulates brain arginine vasotocin immunoreactivity in false clown anemonefish (Amphiprion ocellaris). Fish Physiology and Biochemistry, 36(3), 337-345.
42. Joly-Mascheroni, R. M., Senju, A., & Shepherd, A. J. (2008). Dogs catch human yawns. Biology Letters, 4, 446-448.
43. Keri, S. & Benedek, G., (2009). Oxytocin enhances the perception of biological motion in humans. Cognitive, Affective & Behavioral Neuroscience 9, 237-241.
44. Kime, N. M., Whitney, T. K., Ryan, M. J., Rand, A. S., & Marler, C. A. (2010). Treatment with arginine vasotocin alters mating calls and decreases call attractiveness in male túngara frogs. General and Comparative Endocrinology, 165, 221-228.
45. Knafo, A., Israel, S., Darvasi, A., Bachner-Melman, R., Uzefovsky, F., Cohen, L., et al. (2008). Individual differences in allocation of funds in the dictator game associated with length of the arginine vasopressin 1 a receptor RS3 promoter region and correlation between RS3 length and hippocampal mRNA. Genes, Brain and Behavior, 7, 266-275.
46. Large, E. W., & Snyder, J. S. (2009). Pulse and meter as neural resonance. Annals of the New York Academy of Science, 1169, 46-57.
47. Larson, E. T., O'Malley, D. M., & Melloni, R. H., Jr. (2006). Aggression and vasotocin are associated with dominant-subordinate relationships in zebrafish. Behavioural Brain Research, 167, 94-102.
48. Lee, R., Ferris, C., Van de Kar, L. D., & Coccaro, E. F. (2009) Cerebrospinal fluid oxytocin, life history of aggression, and personality disorder. Psychoneuroendocrinology, 34, 1567-1573.
49. Levin, R., Heresco-Levy, U., Bachner-Melman, R. Israel, S., Shalev, I., & Ebstein, R. P. (2009). Association between arginine vasopressin 1a receptor (AVPR1a) promoter region polymorphisms and prepulse inhibition. Psychoneuroendocrinology, 34, 901-908.
50. Levitin, D. J. (2005). Musical behavior in a neurogenetic developmental disorder:Evidence from Williams syndrome. Annals of the New York Academy of Science, 1060, 325-334.
51. Manuck S. B., Marsland A. L., Flory J. D., Gorka A., Ferrell R. E., & Hariri A. R. (2010). Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgenreceptor gene predict amygdala reactivity in men. Psychoneuroendocrinology, 35, 94-104.
52. Marazziti, D., Masala, I., Baroni, S., Polini, M., Massimetti, G., Giannaccini, G., et al. (2010). Male axillary extracts modify the affinity of the platelet serotonin transporter and impulsiveness in women. Physiology and Behavior, 100, 364-368.
53. Marlowe FW, Berbesque JC. (2008). More 'altruistic' punishment in larger societies. Proc Biol Sci. 275, 587-90.
54. McDermott, R., Christakis, N. A., & Fowler, J. H. (2009). Breaking up is hard to do, unless everyone else is doing it too: Social network effects on divorce in a longitudinal sample followed for 32 years. Retrieved from
55. Meyer-Lindenberg, A., Kolachana, B., Gold, B., Olsh, A., Nicodemus, K. K., Mattay V., et al. (2009). Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans. Molecular Psychiatry, 14, 968-75.
56. Ohashi, J., Naka, I., & Tsuchiya, N. (2011). The Impact of Natural Selection on an ABCC11 SNP Determining Earwax Type. Moledular Biology and Evolution 28, 849-857.
57. Palmieri, L., Papaleo, V., Porcelli, V., Scarcia, P., Gaita, L., Sacco R., et al. (2010). Altered calcium homeostasis in autism-spectrum disorders: Evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1. Molecular Psychiatry, 15, 38-52.
58. Patel, A. D., Iverson, J. R., Bregman, M. R., & Schultz, I. (2009). Experimental evidence for synchronization to a musical beat in a nonhuman animal. Current Biology, 19, 827-830; supplemental data, Movie S1. Synchronization to Music in Experimental Trials at Three Tempi (MOV 6380 kb), retrieved from
59. Patel, et al. (2009). Experimental evidence for synchronization to a musical beat in a nonhuman animal. Current Biology. doi:10.1016/j.cub.2009.03.038
60. Patel, et al. (2008). Studying synchronization to a musical beat in nonhuman animals. Annals of the New York Academy of Sciences. Retrieved from
61. Penenberg, Adam L., "Social Networking Affects Brains Like Falling in Love," Fast Company July 1, 2010 (downloaded from: )
62. Perry, A., Bentin, S., Shalev, I., Israel, S., Uzefovsky, F., Bar-On, D., Ebstein, R.P. (2010). Intranasal oxytocin modulates EEG mu/alpha and beta rhythms during perception of biological motion. Psychoneuroendocrinology 35, 1446-53.
63. Prehn-Kristensen, A., Wiesne, C., Bergmann, T. O., Wolff, S., Jansen, O., Mehdorn, H. M., et al. (2009). Induction of empathy by the smell of anxiety. PLoS ONE, 4, e5987.
64. Preti, G., & Leyden, J. J. (2010). Genetic influences on human body odor: From genes to the axillae. Journal of Investigative Dermatology, 130, 344-346.
65. Raafat, R. M., Chater, N., & C. Frith, (2009). Herding in humans. Trends in Cognitive Sciences, 13, 420-428; (Correction: Trends in Cognitive Neurosciences, 13, 504).
66. Robinson, P. H., Cahill, M. T., & Bartels, D. M. (2009, September 20). Competing theories of blackmail: An empirical research critique of criminal law theory. University of Pennsylvania Law School, Public Law Research Paper No. 09-27; Brooklyn Law School, Legal Studies Paper No. 171. Retrieved from
67. Rodrigues, S. M., Saslow, L. R., Garcia, N., John, O. P., & Keltner, D. (2009). Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans. Proceedings of the National Academy of Science, USA, 106, 21437-21441.
68. Salimpoor, V. N., Benovoy, M., Longo, G., Cooperstock, J. R., Zatorre, R. J. (2009). The rewarding aspects of music listening are related to degree of emotional arousal. PLoS ONE, 4, e7487.
69. Salmina, A.B., Lopatina, O., Ekimova, M.V., Mikhutkina, S.V., & Higashida, H. (2010). CD38/Cyclic ADP-ribose System: A New Player for Oxytocin Secretion and Regulation of Social Behaviour. Journal of Neuroendocrinology, 22, 380-392.
70. Saucier, D. A., & Webster, R. J. (2010). Social vigilantism: Measuring individual differences in belief superiority and resistance to persuasion. Personality and Social Psychology Bulletin, 36, 19-32.
71. Seip, E. C., van Dijk, W. W., & Rotteveel, M. (2009). On hot heads and Dirty Harries: The primacy of anger in altruistic punishment. Annals of the New York Academy of Science, 1167, 190-6.
72. Seltzer, L. J., Ziegler, T. E., & Pollak, S. D. (2010). Social vocalizations can release oxytocin in humans. Proceedings of the Royal Society. B. Biological Sciences. doi:10.1098/rspb.2010.0567
73. Senju, A., Kikuchi, Y., Akechi, H., Hasegawa, T., Tojo, Y., & Osanai, H. (2009). Brief report:Does eye contact induce contagious yawning in children with autism spectrum disorder? Journal of Autism and Developmental Disorders, 39, 1598-602.
74. Senju, A., Southgate, V., White, S., & Frith, U. (2009). Mindblind eyes: An absence of spontaneous Theory of Mind in Asperger syndrome. Science, 325, 883-885.
75. Shamay-Tsoory, S. G., Fischer, M., Dvash, J., Harari, H., Perach-Bloom, N., & Levkovitz, Y. (2009). Intranasal administration of oxytocin increases envy and schadenfreude (gloating). Biological Psychiatry, 66, 864-70.
76. Singer, T., & Steinbeis, N. (2009). Differential roles of fairness- and compassion-based motivations for cooperation, defection, and punishment. Values, Empathy, and Fairness across Social Barriers: Annals of the New York Academy of Science, 1167, 41-50.
77. Soley, G., & Hannon, E. E. (2010). Infants prefer the musical meter of their own culture: a cross-cultural comparison. Developmental Psychology, 46, 286-92.
78. Spitzer, M., Fischbacher, U., Herrnberger, B., Grön, G., & Fehr E. (2007). The neural signature of social norm compliance. Neuron, 56, 185-96.
79. Tamma, R., Colaianni, G., Zhu, L. L., DiBenedetto, A., Greco, G., Montemurro, G., et al. (2009). Oxytocin is an anabolic bone hormone. Proceedings of the National Academy of Science USA, 106, 7149-7154.
80. Tobin, V. A., Hashimoto, H., Wacker, D. W., Takayanagi, Y., Langnaese, K., Caquineau, C., et al. (2010). An intrinsic vasopressin system in the olfactory bulb is involved in social recognition. Nature, 464, 413-417.
81. Toyoda, Y., Sakurai, A., Mitani, Y., Nakashima, M., Yoshiura, K., Nakagawa, H., et al. Earwas, osmidrosis, and breast cancer: Why does one SNP (538GA) in the human ABC transporter ABCC11 gene determine earwax type? The FASEB Journal, 23, 2001-2013.
82. Ukkola, L. T, Onkamo, P., Raijas, P., Karma, K., & Järvelä, I. (2009). Musical aptitude is associated with AVPR1A-haplotypes. PLoS ONE, 4, e5534.
83. Walum, H., Westberg, L., Henningsson, S., Neiderhiser, J. M., Reiss, D., Igl, W., et al. (2008). Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans. Proceedings of the National Academy of Science USA, 105, 14153-6.
84. Way, B. M., Taylor, S. E., & Eisenberger, N. I. (2009). Variation in the mu-opioid receptor gene (OPRM1) is associated with dispositional and neural sensitivity to social rejection. Proceedings of the National Academy of Science USA, 106, 15079-84.
85. Wirén, A., Gunnarsson, U., Andersson, L., & Jensen, P. (2009). Domestication-related genetic effects on social behavior in chickens - effects of genotype at a major growth quantitative trait locus. Poultry Science, 88, 1162-1166.
86. Wray, G. A. (2007). The evolutionary significance of cis-regulatory mutations. Nature Reviews, Genetics, 8, 206-216.
87. Wray, M., Miller M., Gurvey J., Carroll J., & Kawachi I. (2008). Leaving Las Vegas:Exposure to Las Vegas and risk of suicide. Social Science and Medicine, 67, 1882-1888.
88. Young, L. I., & Wang, Z. (2004). The neurobiology of pair bonding. Nature Neuroscience, 7, 1048-1054.
89. Zak, P. J., Kurzban, R., Ahmadi, S., Swerdloff, R. S., Park, J., et al. (2009). Testosterone administration decreases generosity in the ultimatum game. PLoS ONE, 4, e8330.