Rapid screening of aminopeptidase N inhibitors by capillary electrophoresis with electrophoretically mediated microanalysis

Electrophoresis

Volumn 36, Issue 2, 2015, Pages 319-325

  Wang, Hairong ^a   Xu, Wenfang ^a   Cao, Jiangying ^a   Wang, Weihong ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Aminopeptidase N; Electrophoretically mediated microanalysis; Inhibitor screening; Kinetic constants

Indexed keywords

CAPILLARY ELECTROPHORESIS; KINETICS; MICROANALYSIS;

AMINO PEPTIDASE; AMINOPEPTIDASE N; CONDITION; ELECTROPHORETICALLY MEDIATED MICROANALYSIS; HIGH SENSITIVITY; INHIBITOR SCREENINGS; KINETIC CONSTANT; KINETIC CONSTRAINTS; PARTIAL FILLING; RAPID SCREENING;

AMINO ACIDS;

AMINO ACID; BESTATIN; ENZYME INHIBITOR; LEVO LEUCINE 4 NITROANILIDE; MICROSOMAL AMINOPEPTIDASE; MICROSOMAL AMINOPEPTIDASE INHIBITOR; UNCLASSIFIED DRUG; 1-LEUCINE-4-NITROANILIDE; ANILIDE; LEUCINE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; ELECTROPHORETICALLY MEDIATED MICROANALYSIS; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; IC50; INHIBITION CONSTANT; MICROANALYSIS; SPECTROPHOTOMETRY; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; ATOMIC ABSORPTION SPECTROMETRY; DRUG SCREENING; KINETICS; METABOLISM; PROCEDURES; REPRODUCIBILITY;

ANILIDES; ANTIGENS, CD13; DRUG EVALUATION, PRECLINICAL; ELECTROPHORESIS, CAPILLARY; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; KINETICS; LEUCINE; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ATOMIC;

EID: 84921593867     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201400283     Document Type: Article

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