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Volumn 21, Issue 9, 2013, Pages 2663-2670
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Novel indoline-2,3-dione derivatives as inhibitors of aminopeptidase N (APN)
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Author keywords
Aminopeptidase N; Indoline 2,3 dione derivatives; Inhibitors; QSAR; Synthesis
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Indexed keywords
2 [5' BROMO 2' OXOSPIRO([1,3]DIOXANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' BROMO 2' OXOSPIRO([1,3]DIOXEPANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' BROMO 2' OXOSPIRO([1,3]DIOXOLANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' CHLORO 2' OXOSPIRO([1,3]DIOXANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' CHLORO 2' OXOSPIRO([1,3]DIOXEPANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' CHLORO 2' OXOSPIRO([1,3]DIOXOLANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' FLUORO 2' OXOSPIRO([1,3]DIOXALANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' FLUORO 2' OXOSPIRO([1,3]DIOXANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
2 [5' FLUORO 2' OXOSPIRO([1,3]DIOXEPANE 2,3' INDOLINE) 1' YL] N HYDROXYACETAMIDE;
BESTATIN;
HISTONE DEACETYLASE;
INDOLE DERIVATIVE;
INDOLINE 2,3 DIONE DERIVATIVE;
MICROSOMAL AMINOPEPTIDASE;
N HYDROXY 2 [2' OXOSPIRO([1,3]DIOXALANE 2,3' INDOLINE) 1' YL]ACETAMIDE;
N HYDROXY 2 [2' OXOSPIRO([1,3]DIOXANE 2,3' INDOLINE) 1' YL]ACETAMIDE;
N HYDROXY 2 [5' METHYL 2' OXOSPIRO([1,3]DIOXALANE 2,3' INDOLINE) 1' YL]ACETAMIDE;
UNCLASSIFIED DRUG;
VORINOSTAT;
ANTIANGIOGENIC ACTIVITY;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
DRUG DESIGN;
DRUG POTENCY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME INHIBITION;
HUMAN;
HUMAN CELL;
MOLECULAR DOCKING;
ANTIGENS, CD13;
DOSE-RESPONSE RELATIONSHIP, DRUG;
HUMANS;
INDOLES;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
PROTEASE INHIBITORS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84876142876
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.06.024 Document Type: Article |
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Times cited : (25)
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References (13)
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